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CNS Pharmacology
CNS and medication
| Question | Answer |
|---|---|
| what is the area at the end of the neuron to where the nerve impulse travels | synapse |
| what are the chemicals that allow nerve impulses to cross the synaptic cleft | neurotransmitters |
| what is the degenerative disorder of the CNS caused by the death of neurons that produce the brain neurotransmitter dopamine | parkinson's disease |
| parkinson's disease signs/symptoms | tremors, muscle rigidity, bradykinesia (most noticeable of all symptoms), postural instability |
| what neurotransmitter is lacking with Parkinson's which cause the uncoordinated movement | dopamine |
| what are examples of medications are used for the treatment of Parkinson's disease | Dopamine agonist-carbidopa/levadopa(Sinamet), amantadine (Symmetrel)Anticholinergics (Artane, Cogentin) |
| what neurotransmitter is associated with Alzheimer's disease? | acetylcholine |
| acetylcholinesterase inhibitors for alzheimers | donepezil hydrocholoride (Aricept), rivastigmine tartrate (Exelon) |
| Hydantoins medication for seizures | Hydantoins medications phenytoin (Dilantin), |
| Side effects of phenytoin | gingintival hyperplasia |
| What does Gaba(your mama) do | Inhibitory neurotransmitter that quiets the nerves. |
| Common side-effects of Gaba agonist | Your mama says S-T-O-P it.. Quiet!. S-suicide, T-tremors, O-optic changes, P-puzzeled (confused) (Note: when Gaba increased, Dopamine decreased) |
| Example of antiseisure medication that potentiate GABA-Barbituate | phenobarbital (Luminal), |
| Example of antiseisure medication that potentiate GABA-Benzodiazeipines | diazepam (Valium), lorazepam (Ativan), clonazepam (Klonopin) |
| Example of antiseisure medication that potentiate GABA-Benzodiazeipines | gabapentin (Neurontin), pregabablin (Lyrica), tiagabine (Gabitril), topiramate (Topamax) |
| Side-effects for benzodiazepines "Pams" | sedation, confusion, decrease vital signs, headache, and sensitivity to light , Assess respiration s! |
| Antiseizure drugs that potentiate GABA action - Newer GABA related drugs | gabapentin (Neurontin), pregabablin (Lyrica), tiagabine (Gabitril), topiramate (Topamax) |
| central nervous system is made up of | the division of the nervous system consisting of the brain and spinal cord |
| peripheral nervous system | the division of the nervous system consisting of all of the nerves located outside the central nervous system |
| somatic nervous system | the group of nerves in the peripheral nervous system that controls voluntary actions |
| autonomic nervous system | the group of nerves in peripheral nervous system that controls involuntary actions. |
| 2 branches of the autonomic nervous system | Sympathetic and Parasympathetic |
| Actions body takes for fight/flight(SNS) | Hypertension, tachycardia, eyes dilate, |
| Actions body takes with Parasympathetic nervous system | SLUD..s-salivation, L-lacrimation/learning, U-urination, Defication |
| degenerative inflammatory disease of the CNS attacking the myelin sheath in the spinal cord and brain | Multiple sclerosis-MS |
| Central Nervous Stimulant used for ADHD | Amphetamine, Dextroamphetamine-(Adderall ) methylphenidate (Ritalin) |
| Side-effects of CNS stimulants | nervousness, irritability, increased blood pressure and pulse |