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various Diuretics
diuretics
| Question | Answer |
|---|---|
| Vasopressin | used to manage diabetes insipidus |
| Vasopressin | cardiac related adverse effects |
| Desmopressin | analog used for nocturnal enuresis |
| mannitol | administerd IV only |
| mannitol | used for prophlaxis of acute renal failure |
| mannitol | useful for reducing cerebral edema and intraocular pressure |
| Glycerin and isosrbide | administered orally and used for opthalmic procedures |
| Carbonic Anyhdrase inhibitors | metabolic acidosis, Potassium wasting, contraindicated in presence of hepatic cirrhosis |
| Carbonic anhydrase inhibitors | used for glaucoma, siezure disorders, enhance renal secretion of uric acid and cystiene, and acute mountian sickness |
| Carbonic Anyhydrase inhibitors | acetozolamide, dichlorphenamide--> sulfonamide derivatives |
| potassium sparing diuretics | interfere with potassium secretion and sodium reabsoption |
| potassium sparing diuretics | not potent when used alone |
| potassium sparing diuretics | used primarily in combination with other siuretics |
| Spironolactone | structural analog of aldosterone |
| spironolactone | absorbed by GI, metabolized in liver |
| amiloride and triamterene | used for CHF and cirrhosis |
| carbonic anhydrase inhibitors | reduce HCO3 reabsoprtion and concomitant soduim uptake |
| carbonic anhydrase inhibitors | inhibits excretion of hydrogen |
| Carbonic anhydrase inhibitors | absorbed from GI, secreted by proximal tubule |
| loop diuretics | hypotension, volume depletion, hypokalemia, alkalosis, mag. wasting, ototoxicity |
| loop diuretics | used for acute pulmonary edema and CHF when coadministerd with thiazide, HTN, hypercalcemia and halide poisoning |
| loop diuretics | furosemide, piretanide, bumetanide, ethacrynic acid, torsemide |
| loop diuretics | absorbed by GI or given parenterally |
| loop diuretics | inhibit sodium chloride reabsorption in thick ascending limb and increase potassium, magnesium, anc calcuim excretion |
| thiazides | used with caution in renal or hepatic disease |
| thiazides | hypokalemia, hyponatremia, hypochloremic alkalosis, elevated serum urate, hyperglycemia, hypersensitivity |
| thiazieds | used for HTN, hypercalciuria and diabetes insipidus |
| thiazides | often used in combination with potassium sparing agents to manage mild cardiac edema, cirrhotic or nephrotic edema, and edema from hormone imbalance |
| thiazides | chlorothiazide, HCTZ, chlorthalidone, benzthiazide, cyclothiazide-->synthetics metolazone and indapamide |
| thiazides | absorbed from GI tract, secreted into lumen of proximal tubule and inhibits active reabsoption of NaCl in the ascending loop of henle while increasing excretion of Cl, Na, K and at high doses HCO3 |
Created by:
swohlers
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