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Final Pharm
| Question | Answer |
|---|---|
| Which factor for transcutaneous administration is NOT an advantage? | expense |
| Adding an inducer drug to a substrate drug already being taken can lead to: | loss of substrate drug clinical effect |
| Augmentin contains clavulanate and____ | amoxicillin |
| Ketek has the potential for: | QT interval prolongation, hepatotoxicity, & blood sugar alteration |
| A patient with an anaphylactic reaction to penicillin can safely be prescribed_____ | doxycycline |
| Biaxin and erythromycin are substrates for: | 1A2 & 3A4 |
| Which antibiotic forms chelates with heavy metals | doxycycline, azithromycin, ciprofloxacin |
| Which antibiotic is NOT an aminoglycoside | vancomycin |
| Which method leads to antibiotic resistance by bacteria? | target modification, active efflux, target elimination |
| Which antifungal agent is NOT a macrolide | Diflucan |
| The 1st line agent for early stage Lyme disease in adults is: | doxycycline |
| The drug used for active TB that can cause body fluids to turn a red-orange color is: | rifampin |
| The ratio of a drug's toxic level to it's therapeutic level is called: | therapeutic index |
| Variations of patient's responses to a drug from normal due to genetic differences is called: | polymorphisms |
| Grapefruit juice is an inhiitor of | 3A4 |
| The class of HIV drugs that block final stages of viral protein synthesis are the: | Protease inhibitors |
| Which agent would NOT be used for malaria prophylaxis | metronidazole |
| A good choice to prescrible for a patient you have diagnosed with shingles is: | Valtrex |
| An agent used to treat patients who have a positive skin test for TB is | INH |
| The antibiotics that work to interfer with bacteria coiling during replication are the: | quinolones |
| Which is NOT a potential side effect of metformin | elevated triglycerides |
| Which is a potential side effect of the glitazones | weight gain, edema, elevated HDL & LDL |
| a typical bottle of insulin contains how many units of insulin | 1,000 |
| Which insulin is NOT clear | NPH |
| 70/30 insulin mix contains | 70% N and 30% R |
| Which is NOT true for Byetta | it causes weight gain |
| Which is NOT a 2nd generation sulfonylurea | Diabinese |
| The 1st line agent for diabetic neuropathy is | Neurontin |
| A pro-motility agent is: | Reglan |
| In diabetic ketoacidosis which agent is appropriate | Humalog |
| Which agent is derived from animal sources | Proloid, Thyrolar, Cytomel |
| Which agent is NOT a gonane? | norethindrone |
| Which COC side effect does NOT reflect excessive androgenic activity | nausea |
| The antibiotic most associated with oral contraceptive failure is: | ampicillin |
| Which are benefit of OC | reduced ovarian and endometrial cancer, reduced dysmenorrhea, fewer ovarian cysts |
| Emergency contraception should contain how much ethinyl estradiol in each does? | 100mcg |
| An herb to recommend for a woman who desires natural agents for dysmenorrhea is: | chaste berry |
| Research has shown that Premarin use is associated with increased: | MIs, DVTs, invasive breast cancer |
| Plan B is effective 89% of the time up to ___ days | 3 |
| Open bottles of Lantus can be kept at room temp and should be discarded after: | 28 days |
| The best thiazide to try for a male patient with sexual dysfunction is: | indapamide |
| The most potent diuretic of these choices for use in edema is | furosemide |
| The upper limit of dosing for furosemide is | 320mg |
| Which is NOT a cardioselective beta blocker? | propranolol |
| ACE-Is are avoided in: | pregancy, bilateral renal stenosis, patients prone to volume depletion |
| Which of the following CCBs is NOT a dihydropyridine? | Calan |
| Which agent would be inappropriate for use in chronic HTN during pregancy? | lisinopril |
| Which drug does have potenital to elevate total cholesterol and LDL? | HCTZ, prednisone, metoprolol |
| Which statin is associated with renal problems? | Crestor |
| Which statin is NOT a substrate for 3A4 | Crestor |
| Which agent typically achieves the greatest HDL elevation | niacin |
| Vytorin combines Zetia with: | simvastatin |
| An undesired effect for cold fish oils is: | elevated LDLs |
| Which agent is usually avoided in HF | non-dihydropyridine |
| Aminodarone is an inhibitor of: | 1A2, 2D6, & 3A4 |
| Which is an advantage of LMWH over unfractionated heparin? | longer t1/2, more predictable response, faster onset |
| Warfarin is an antagonist of Vitamin: | K |
| Which isoenzyme is NOT involved with wargarin metabolism | 2D6 |
| An agent indicated for intermittent claudication is: | pentoxifylline |
| The agent reserved for "last resort use" in refractory HTN is: | minoxidil |
| Antacids have the potential to chelate which drug? | quinolones, tetracyclines, nitrofurantoin |
| Tagamet is a potent inhibitor of | 3A4 |
| Prevpac does NOT contain | erythromycin |
| Zofran targets which receptor? | 5-HT3 |
| Diarrhea is associated with antacids containing | magnesium |
| Constipation is associated with antacids containing | aluminum |
| Which of the following is NOT a stimulative laxative? | Metamucil |
| A concern with prescribing Imuran is | pancreatitis |
| The 1st line agent to remove the fluid of ascites of alcoholic cirrhosis is: | spironolactone |
| Which drug is associated with hepatitis | acetaminophen, INH, methotrexate |
| Which is a potential side effect of pegasys | flu-like symptoms, depression, thrombocytopenia |
| Which natural product is NOT considered hepatotoxic? | milk thistle |
| The mechanism of action of orlistat is to: | interfere with fat absorption |
| Tums contains: | calcim carbonate |
| Which side effect is associated with steriod use? | increase susceptibility to infection, cataracts, irritability |
| Which drug class finds use for nausea/vomiting of chemotherapy | steriods, NK-1 recptor blockers, 5-HT3 receptor blockers |
| The active component of sulfasalazine is: | 5-aminosalicylate |
| Bonine contains: | meclizine |
| A patient of yours going on a cruise should apply a Trans-scop patch how many hours before departure? | 8 |
| according to labeling what is the upper limit for the number of Imodium capsules in 24 hours | 4 |
Created by:
htuden
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