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PHAT 132 A.Dudley

PHAT 132 Mod 4/1 Study Guide

QuestionAnswer
Adverse Drug Reaction Any unexpected obvious change in a patients condition that the physician suspects may be due to a drug
Overdose A toxic dose of a drug or other substance
Side Effect Results of a drug or other therapy in addition to, or in extension of, the desired therapeutic effects which are usally, BUT NOT ALWAYS, undesirable.
Tolerance The bodys slow adaption to a drug, higher and higher doses are required to achieve the same effect; Reduced responsiveness to a drug
Toxicity The state of being noxious refers to drugs ability to poison the body
Half-life The time taken for the blood or plasma concentration of the drug to decrease from full to half.
Adverse affects Harmful effects
Drug Indication The exact reason for the use of a drug
Agonist A drug that binds to a receptor and produces an appropriate physiologic response that is similar to what an endogenous substance would do
Dose-effect relationship The relationship between the dose of a drug (or other agent) that produces harmful effects and the severity of the effects on the patient
Anaphylactic Shock A sudden and severe allergic reaction that may be life threatenting.
Biotransformation The process of conversion of drugs within the body
Bioavailability The degree and rate at which a drug is absorbed in a living system or is made available at the site of physiologic activity.
Pharmacodynamics Study of how drugs interact in the human body
Pharmacokenetics The study of the absorption, distribution, biotransformation, and excretion of drugs.
Pharmacognosy The study of drugs derived from herbal and other natural sources.
Toxicology The study of poisons, their detections, their effects, and establishing antidotes and methods of treatment for conditions they produce
Pharmacotherapeutics The study of how drugs are used in the treatment of disease within the human body
Posology The study of the exact amount of a drug that is needed in order to produce a therapeutic effect.
Pharmacy The study of preparing and dispensing medication
Medication + Medicine These terms refer to drugs mixed in a formulation with other ingredeints to improve the stability, taste or physical form to allow appropriate administration of the active drug
Antagonist An agent that acts in physiologic opposition; in pharmacology it is an agent that prevents an agonist from binding to a receptor, there by blocking its effects
Pharmacology This deals with all of the drugs in society today. Those that are legal, illegal, prescription and OTC.
Blood This is the most commonly sampled bodily fluid used to characterize the pharmacologic action of drugs
Absorption, Metabolism, Excretion, Site of Action, and Observed Response The factors that influence the onset, duration, and intensity of drug effects
Factors that affect drug actions Age, Sex, Body Weight, Diurnal Body Rhythms, Diseases, Allergies, Psychological factors, Drug half-life, Tolerance, Drug toxicity, and Drug interactions
Importance of drug half-life Major determining factor in how often a drug may be given
Importance of age Age effects metabolic rate
Importance rule of thumb when dealing with Pediatric and Geriatric Start low and go slow
Importance of Sex and Gender Drugs that are administered IM are absorbed faster by man than women. Those drugs remain in women's tissues longer than in men's because women have a higer body fat content
Importance of body weight The same dose of medication can have varied affects on patients whose body weights differ. Some medication doses must be adjusted based on body weight or body surface area especially in children
Importance of diurnal body rhythms Circadian rhythm or sleep patterns have a tendancy to intensify a patients response to a medication
Importance of disease Especially of the kidney and liver. The liver is the major site for detoxification and the kidneys are the site for elimination of chemical substances.
Take on and empty stomach Take 1 hour before or either 2 hours after meal.
Created by: shantel.dudley
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