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phat132

mode 4 week 1 study guide bh

6 major areas of Pharmacology
Pharmacodynamics - study of how drugs interact in the human body
Pharmacokenetics - study of the absorption distribution, biotransformation excretion of drugs
Pharmacotherapeutics - study of how drugs are used in the treatment of disease in the human body
Pharmacy - Study of preparing and despensing medications
Posology - study of the exact amt of a drug that is needed in order to produce a therapeutic effect
Toxicology - study of poisons, their detection, their effects and establishing antidots and methods of treatment for conditions they produce
Adverse Affects - harmful effects
Agonist - a drug that binds to a receptor and produces an appropriate physiology response that is similar to what an endogenous substance would do
Anaphylactic Shock - a sudden and severe allergic reaction that may be life threating
Antagonist - an agent that acts in physiologic opposition in pharmacology, it is an agent that prevents an agonist from binding to a receptor, there by blocking its effects
Bioavailability - the degree and rate at which a drug is absorbed into a living system or is made available at the site of physiologic action
Biotransformation - the process of conversion of drugs within the body
Adverse Drug Reaction (ADR) - any unexpected obvious change in the pt. condition that the physician suspects may be due to a drug
Dose Effect Relationship - the relationship between the dose of a drug ( or other agent) that produces harmful effects and the severity of the effects on the pt.
Drug Indication - the exact reason for the use of a drug
Half-life - the time taken for the blood or plasma concentration of the drug to decrease from full to half
Overdose - a toxic dose of a drug or other substance
Side Effects - results of a drug, or other therapy in addition to, or in extension of, the desired therapeutic effects which are usually but not always, undersireble
Tolerance - the bodys slow adaption to a drug, higher and higher doses are req. to achieve the same effect, reduced reponsiveness to a drug
Toxicity - the state of being noxious, refers to a drugs ability to poison the body
NOTES
Pharmacognosy - study of drugs derived from herbal and other natural sources
the term medication refer to drugs mixed in a formalation to follow appropriate adminstration of the active drug
pharmacology deals with w/ all of the drugs in society today, those that are legal, illegal, rx, otc
blood is the most commonly sampled bodily fluid used to characterize the phamacologic action of drugs
the factors that influence the onset duration an intensity of drug effects absorption, metabolism, reabsorption, excreation, site of action and observed response
Factors that affect drug actions age, sex, body, weight, diurnal body rythms, diseases allergies, psychological factors, drug half- life, tolerance drug toxicity and drug interactions
IMPORTANCE OF
Drug half life - this is the major determining factor in how often a drug may be given
Age - age affect metabolic rate importance rule of thumb when dealing w/ pediatric and geriatric pts ( start low go slow)
Sex Gender - drugs administered IM are absorbed faster by men that women. they remain in womens tissues b/c women have a higher body fat content
Body weight - same dose of medication can have varied affects on pts whose body weights differ, some medication doses must be adjusted body we. and body surface area, especially in children
Diurnal Body Rythms - circodian rythms sleep patterns have a tendency to intensify a pt response to medication
Disease - a person w/ a liver or kidney disease may respond to a medication differntly than a healthy person
Created by: bobby.holmes
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