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Pharm Terms ch11

Pandemic events of epidemic proportion that spread across human populations
Bioterrorism intentional use of infectious agents to cause widespread harm
Strategic National Stockpile (SNS) designed to deploy essential medical materials to a community in the event of a large chemical or biologic attack
Vendor Managed Inventory (VMI) after threat has been more clearly identified, meds are sent based on the chemical or biologic agent
Anthrax caused by a bacteria and affects humans and animals by open wound, contaminated food, or inhalation
Vaccine causes body to make protective antibodies preventing the onset of disease and symptoms
Nerve Agents toxic chemical that is most significant - causes convulsions and loss of consciousness within seconds and resp failure within minutes
Ionizing radiation radioisotopes created by nuclear explosion
Acute radiation syndrome radiation sickness causing weight loss, anorexia, fatigue, and bone marrow suppression. - at risk for leukemia
Basic supportive care first elements of toxicity treatment
Syrup of ipecac induces vomiting
Activated charcoal carbon-based molecules absorb to this and minimize absorption
Whole-bowel irrigation considered for toxic ingestion of sustained-release or enteric-coated drugs
Specific antidotes counter effects of poisons
acetylcysteine (Acetadote) antidote for Acetaminophen (nonopioid analgesic)
atropine sulfate antidote for Acetylcholine, cholinergic receptor agents, acetylcholinesterase inhibitors
calcium EDTA (Calcium Disodium Versenate) antidote for lead toxicity
deferoxamine (Desferal) antidote for iron toxicity
digoxin immune Fab (Digibind) antidote for Digoxin
dimercaprol (BAL in Oil) antidote for arsensic, gold and mercury toxicity
flumazenil (Romazicon) antidote for Benzodiazepines
fomepizole (Antizole) antidote for Ethylene glycol toxicity (antifreeze poisoning)
glucagon Antidote for insulin
leucovorin (Wellcovorin) antidote for Methotrexate, folic acid blocking agents
naloxone (Narcan) antidote for opioids agents, morphine
neostigmine (Prostigmin) antidote for neuromuscular blocking agents
penetrate calcium trisodium & penetrate zinc trisodium antidote for radioactive exposure
penicillamine (Cuprimine, Depen) antidote for copper, iron, lead, arsenic, gold, and mercury toxicity
pysotigmine (Antrillium) antidote for cholinergic blocking agents, atropine sulfate
potassium iodide antidote for radioactive exposure, nuclear bomb
protamine sulfate antidote for heparin
prussian blue (Radiogardase) antidote for radioactive cesium-137
succimer (Chemet) antidote for lead, mercury, and arsenic toxicity
vitamin K antidote for Coumadin, warfarin (anticoagulant)