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Pharm Terms ch2
| Term | Definition |
|---|---|
| Formulary | first standard list of drugs and drug recipes used by pharmacists |
| Pharmacopoeia | summarizes standard of drug purity, strength, and directions for synthesis |
| Excipients | inactive ingredients |
| Black box warnings | primary alerts for extreme adverse reactions |
| Preclincal investigation | laboratory research testing on human and microbial cells |
| FDA's Critical Path Initiative | effort to modernize the sciences to enhance the use of bioinformation to improve safety and effectiveness. |
| Clinical investigation | second phase of drug testing - has three stages of of trials |
| Clinical phase trials | longest part of drug approval process - perform tests on volunteers to determine adverse effects |
| New Drug Application (NDA) | must be submitted before a drug is allowed to proceed |
| Investigational New Drug (IND) | may be submitted for Phase I clinical trials when there are significant therapeutic benefits and safe for humans |
| New Drug Application (NDA) review | third phase of drug approval process; trade name is finalized |
| Postmarketing surveillance | final phase of drug approval process; purpose is to survey for harmful drug effects in a larger population |
| Dependence | physiological or psychological need for a substance |
| Physical dependence | altered physical condition when the drug is no longer available |
| Psychologically dependent | intense desire to continue drug use |
| Controlled substance | use is restricted by the Controlled Substance Act |
| Scheduled drugs | 5 classifications according to their potential for abuse |
| Schedule I Drugs | highest potential for abuse |
| Schedule V Drugs | lowest potential for abuse |
| Teratogenic risk | drugs that have potential to harm fetus; categories A, B, C, D, X |
| Category X Teratogenic drug | poses most danger to fetus |