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Autonomic Pharm
WVSOM Autonomics Pharmacology
| Question | Answer |
|---|---|
| Brimonidine | (Alphagan) a2 selective agonists – used topically on the eye |
| Apraclonidine | (lopidine) a2 selective agonists – used topically on the eye |
| Xylometazoline | a1 selective agonists(Chlorohist-LA, Inspire, Neo-Synephrine II Long Acting, Otrivin) Used nasally |
| Oxymetazoline | a1 selective agonists (Afrin, Neo-Synephrine 12 Hours, etc.) – also activate a2. Used for nasal |
| Midodrine | a1 selective agonists(ProAmatine) – oral |
| Brimonidine | (Alphagan) a2 selective agonists – used topically on the eye |
| Apraclonidine | (lopidine) a2 selective agonists – used topically on the eye |
| Isoproterenol | non-selective Beta agonist (must be given parentally) |
| Dobutamine | Beta1 selective agonist, also acts on some Beta2's and alpha receptors (must be given parentally) |
| Albuterol | (Proventil, Ventolin, etc.) b2 selective agonists – given as inhalation |
| Metaproterenol | (Alupent, Metaprel, etc.) b2 selective agonists – given as inhalation |
| Bitolterol | (Tornalate) b2 selective agonists – given as inhalation |
| Pirbuterol | (Maxair) b2 selective agonists– given as inhalation |
| Terbutaline | (Brethine, Bricanyl, etc.) b2 selective agonists. Can be given orally or parentally |
| Salmeterol | (Serevent) – b2 selective agonists. Given as inhalation |
| Formoterol | (Foradil Aerolizer, Foradil Certihaler) b2 selective agonists. given as inhalation |
| Arformoterol | (Brovana) b2 selective agonists. given as inhalation |
| Phenylephrine | Topical Nasal Decongestant - acts on a1'sSHORT DURATION |
| Xylometazoline | Topical nasal decongestant - acts on a1'sLong duration |
| Oxymetazoline | topical nasal decongestant -acts on a1'sLong duration |
| Prazosin | (Minipress) - a1 selective antagonist, reversible |
| Terazosin | (Hytrin)a1 selective antagonist , reversible |
| Doxazosin | (Cardura)a1 selective antagonist, reversible |
| Tamsulosin | (Flomax)a1 selective antagonist , reversible |
| Alfuzosin | (Uroxatral)a1 selective antagonist, reversible |
| Phentolamine | Non-selective alpha antagonist REVERSIBLE |
| Phenooxybenzamine | nonselective alpha antagonist IRREVERSIBLE |
| Prazosin (Minipress) | alpha-antagonist - used to treat hypertension |
| Terazosin | alpha antagonist - used to treat hypertension |
| Doxazosin | alpha antagonist- used to treat hypertension |
| Phentolamine | alpha antagonist - used to treat pheochromocytoma |
| Phenoxybenzamine | alpha Antagonist - used to treat pheochromocytoma |
| What are the three drugs used to treat pheochromocytoma | Prazosin, Phentolamine, and Phenoxybenzamine |
| Terazosin | - Trests BPH (a-blocker) |
| Doxazosin | - Treats BPH (a-blocker) |
| Tamsulosin | - Treats BPH (a-blocker) |
| Alfuzosin | - treats BPH (a-blocker) |
| Prazosin | a-blocker, used to treat Raynauds |
| Propranolol | (Inderal) - b Receptor Antagonists: Non-selective, competitive, reversible |
| Nadolol | (Corgard) - b Receptor Antagonists: Non-selective, competitive, reversible |
| Timolol | (Blocadren, Timoptic, Betimol) - b Receptor Antagonists: Non-selective, competitive, reversible |
| Pindolol | (Visken) - b Receptor Antagonists: Non-selective, competitive, reversible |
| Carteolol | (Cartrol, Ocupress) - b Receptor Antagonists: Non-selective, competitive, reversible |
| Levobunolol | (Betagan) - b Receptor Antagonists: Non-selective, competitive, reversible |
| Metoprolol | (Lopressor, Toprol XL) - b1 selective, competitive, reversible |
| Atenolol | (Tenormin) - b1 selective, competitive, reversible |
| Acebutolol | (Sectral) - b1 selective, competitive, reversible |
| Betaxolol | (Betoptic, Kerlone) - b1 selective, competitive, reversible |
| Levobetaxolol | (Betaxon)The S-isomer of racemic betaxolol. b1 selective, competitive, reversible |
| Bisoprolol | (Zebeta)- b1 selective, competitive, reversible |
| Esmolol | (Brevibloc) - b1 selective, competitive, reversible |
| What is BEAM used to identify | ALL B1 antagonist start with B E A or M |
| Acetylcholine | Direct Acting Muscarinic Agonists |
| Methacholine | Direct Acting Muscarinic Agonists |
| Bethanechol | (Urecholine) - Direct Acting Muscarinic Agonists. Works specfically on the badder and GI tract |
| Pilocarpine | (Pilocar, Etc., - topical/ Salagen - oral) - Direct Acting Muscarinic Agonists |
| Carbachol | (Isopto Carbachol, Carboptic, Miostat) - direct acting muscarinic agonsit |
| Cevimeline | (Evoxac) - direct acting muscarinic agonist |
| Muscarine | Direct acting muscarinic agonist |
| Why is ACh not used as a drug | Short half-life, way too non-specific, and not very good at reaching target |
| What is Bethanechol used for | works on the bladder and GI tract |
| Can Bethanechol be used for obstructive GI problems | NO, only used for non-obstrutive |
| Pilocarpine is used orally to treat what | Radiation caused dry mouth and Sjogrens syndrome |
| Pilocarpine is used topically to treat what | Open and narrow angle glocoma, and caue Miotic effects |
| What advatages does Cevimeline have over pilocarpine | Long lasting, less side effects and only needs to be taken 2-3 times per day |
| What is Carbachol | 2nd line drug in the treatment of glocoma |
| Donepezil | (Aricept, Aricept ODT)- Reversible AChE Inhibitors. WORKS ON CNS |
| Tacrine | (Cognex)- Reversible AChE Inhibitors. WORKS ON CNS |
| Rivastigmine | (Exelon) - Reversible AChE Inhibitors. WORKS ON CNS |
| Galantamine | (Razadyne)- Reversible AChE Inhibitors. WORKS ON CNS |
| (Mestinon, Mestinon Timespan)- Reversible AChE Inhibitors | |
| Ambenonium | (Mytelase)- Reversible AChE Inhibitors |
| Demecarium | (Humorsol) - Reversible AChE Inhibitors |
| Donepezil | (Aricept, Aricept ODT)- Reversible AChE Inhibitors. WORKS ON CNS |
| Tacrine | (Cognex) - Reversible AChE Inhibitors. WORKS ON CNS |
| Rivastigmine | (Exelon) - Reversible AChE Inhibitors. WORKS ON CNS |
| Galantamine | (Razadyne) - Reversible AChE Inhibitors. WORKS ON CNS |
Created by:
lowryc
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