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Pharm test 1 adrener
Pharm. Ch 17-18 by lilk8tob
| Definition | Word |
|---|---|
| drugs that stimulate the sympathetic nervous system. | adrenergics |
| Adrenergics are also called: (2) | adrenergic agonists or sympathomimetics because they mimic the effects of the sympathetic neurotransmitters norepinephrine and epinephrine |
| adrenergic receptors that are further divided into alpha1- and alpha2-adrenergic receptors and are differentiated by their location on nerves | alpha-adrenergic receptors |
| Bodily functions that are involuntary and result from physiologic activity of the ANS. | autonomic functions |
| Controls autonomic bodily functions | autonomic nervous system (ANS) |
| Located on postsynaptic effector cells- the cells, muscles, and organs that the nerves stimulate. | Beta-adrenergic receptors |
| Beta1-adrenergic receptors are primarily in: | the heart |
| beta2-adrenergic receptors are located in the: | smooth muscle of the bronchioles and arterioles and in visceral organs |
| substances that can produce a sympathomimetic response. They are either endogenous catecholamines (such as epinephrine, norepinephrine, and dopamine) or synthetic catecholamines. | catecholamines |
| adrenergic receptors that, when stimulated by dopamine, cause the renal, mesenteric, coronary, and cerebral arteries to dilate and the flow of blood to increase | dopaminergic receptors |
| pupillary dilation, whether natural (physiologic) or drug-induced | mydriasis |
| topically applied eye medications | ophthalmics |
| refers to an increased heart rate | positive chronotropic effect |
| causes an increase in conduction through the atrioventricular node | positive inotropic effect |
| the space between the nerve ending and the effector organ | synaptic cleft |
| paroxysmal chest pain caused by myocardial ischemia | angina |
| drugs that bind to adrenergic receptors and inhibit or block neurotransmitters | antagonists |
| the characteristic of beta-blockers to inhibit stimulation of the heart by circulating catecholamines | cardioprotective |
| beta-blocking drugs that are selective for beta1-adrenergic receptors. | cardioselective beta-blockers |
| cardioselective beta-blockers are also called: | beta1-blocking agents |
| irregular heartbeat | dysrhythmia |
| leaking of fluid from the blood vessel into the tissues | extravasation |
| the production of glucose from glycogen in the liver, which is reduced by beta-blockers | glycogenolysis |
| action of agents within the beta-blocking class. A drug that mimics the activity of the adrenergic system | intrinsic sympathomimetic activity (ISA) |
| attraction to lipid or fat | lipophilicity |
| beta-blocking drugs that block both beta1- and beta2-adrenergic receptors | nonselective beta-blockers |
| abnormally low blood pressure occuring when a person assumes the standing position | orthostatic hypotension |
| drugs used to treat postpartum and postabortion bleeding caused by uterine relaxation and enlargement. They stimulate the smooth muscle of the uterus to contract | oxytocics |
| vascular tumor that secretes norepinephrine and stimulates the CNS | pheochromocytoma |
| another name for adrenergic antagonists | sympatholytics |
| system of classifying antidysrhythmic agents | Vaughan Williams classification |
| Albuterol (*) | Ventolin |
| Epinephrine (*) | Adrenalin |
| Pseudoephedrine (*) | Afrin |
| Dobutamine (*) | Dobutrex |
| Albuterol is a (category) | selective beta2 adrenergic |
| Epinephrine is a (cat.) | natural mixed alpha and beta |
| Pseudoephedrine is a (cat.) | stereoisomer of ephedrine |
| Dobutamine is a (cat.) | beta1-selective vasoactive adrenergic drug similar to natural dopamine |
| Albuterol effect | bronchodilator |
| Epiniphrine effects | vasoconstriction, increased BP, cardiac stimulation, dilation of bronchioles |
| Pseudoephedrine effect | nasal decongestant |
| Dobutamine effect | increases cardiac output by increasing contractility (positive inotropy), which increases stroke volume |
| metaprolol (*) | Lopressor |
| propranolol (*) | Inderal |
| sotalol (*) | Betapace |
| phentolamine (cat.) | alpha blocker |
| prazosin (cat.) | alpha1-adrenergic blocker |
| metaprolol (cat.) | beta1-blocker |
| propranolol (cat.) | nonselective beta1 and beta2 blocker |
| sotalol (cat.) | nonselective beta blocker |
| phentolamine effect | reduces peripheral vascular resistance |
| phentolamine used to treat | hypertension, pheochromocytoma, extravasation of vasopressors |
| prazosin effect | relaxes & dilates the vasculature & smooth muscle around the prostate |
| prazosin uses | hypertension, urinary obstruction in men w/ BPH |
| metaprolol uses | post-MI, hypertension, early MI |
| propranolol uses | angina, hypertension, dysrhythmias, post MI, migraine, tremor, pheochromocytoma |
| sotalol effect | antidysrhythmic |
| sotalol uses | difficult to treat dysrhythmias |
Created by:
lilk8tob
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