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Aseptic Techniques

Certain procedures carried out during the preparation of a sterile product to minimize contamination Aseptic Technique
Means "taking place in a hospital" Nosocomial
What is the most frequent cause of contamination? The person compounding
This type of filter removes large particles and resembles a residential air conditioner filter. Pre-Filter
This type of filter removes 99.97% of particles and microorganisms 0.3 microns or larger. HEPA Filters
HEPA filters must be replaced: on a regular basis
HEPA filters require regular maintenance : every six months
JCAHO requires maintenance: every 12 months
Air flows horizontally across work area Horizontal Hood
Air flows downward onto the surface of work area, safer for the compounder Vertical Hood
Parts of a syringe: plunger, barrel, tip for needle attachment, markings for measurement, top collar, flat end
Syringe sizes range from: 1-100 ml
When measuring parental medication, always use the syringe that: is closest to the amount that needs to be measured.
This type of syringe is the most commonly used. Plastic syringe
What two factors are considered when deciding what type of syringe should be used? Compatibility and cost
Parts of a needle: Shaft, Hub, Bevel
Outside diameter is the _____ of the needle. gauge
The larger the gauge number the _____ the diameter. smaller
The smaller the gauge number the ____ the diameter. larger
Injections bypasses the: alimentary (digestive) canal
Disadvantages of parental routes: risk of infection, tissue damage, pain/anxiety
Drug is injected into superficial layer of skin/most commonly used: Intradermal
Injected into arteries: Intra-arterial
Injected into heart: Intracardiac
Injected into joint: Intra-articular
Injected into spinal cord: Intrasynovial
Injected into brain-spinal cord: Intrathecal
D5W/D10W 5% dextrose in water/10% dextrose in water
0.9% Sodium Chloride
Having the same osmotic pressure as another solution Isotonic
1/2 NS = 0.45% Sodium Chloride
Sodium Chloride/NS is isotonic with _____. blood
Used for reconstitution Sodium Chloride, Sterile Water
Hypotonic solutions have a ______ osmotic pressure than red blood cells. lower
Used for patient fluid replenishment. Ringer's Solution
Drug is injected in the loose tissue beneath the skin: Subcutaneous (SC or SQ)
Drug is injected into muscle mass: Intramuscular
Drug is administered into the veins: Intravenous (IV)
With the exception of lipids, IV injections of solutions that are "_____________" should not be administered. cloudy in appearance
When should you disinfect the hood? At the beginning and end of work shift, hourly during operation, and after spills or known contaminaiton
The Laminar Air Flow Hood should be running for at least _____ minutes before using. 30
You must work at least _____ inches within the hood. six
Avoid working over _________ to prevent contamination fall into preparation area. open containers
Blocking areas of preparation that must remain sterile from the air flow, thus allowing for contamination is called: Shadowing
Areas behind objects in the airflow. Dead spaces
Sterile product preparation room should be free of ______, especially _____ as a source of particles. dust, cardboard
Sterile room should be kept away from ___________. common routes of personnel traffic
While laminar air flow hoods prevent airborne contamination, they do not __________. guarantee a sterile products
Prior to compounding, remove rings, watches, and bracelets which are ideal for _______ to hide. bacteria
While working in the hood, do not introduce items that are not _________ for the preparation (ex. papers, pencils). essential
For drugs in a vial in powder form. it is necessary to reconstitute with a suitable ______. diluent
Prior to compounding, wash hands and forearms to the elbows with the appropriate ________ agent. This should be done for at least ______. germicidal, 30 seconds
When introducing liquid into a plastic IV bag, the needle must be at least _____ inches to penetrate the diaphragm. 1/2
Containers made entirely of glass. Ampule
When withdrawing liquid from a vial, remove the cover of the vial and wipe rubber surface with an ______________. alcohol swab
Before withdrawing necessary amount of liquid from a vial, you should withdraw the same volume of __________ into the syringe, air
What should you do when there are air bubbles in the syringe? Tap the syringe to make all of the bubbles go to the top, then pull down and back up to remove it
Do not _____ needles. clip, bend, or recap
How should you open an ampule? Hold the ampule neck with a gauze and snap it open quickly.
A _______ should always be used when withdrawing from an ampule to prevent glass particles from getting into the liquid. filter straw/needle
In preparation of parental products, do not ______, thoroughly _____ instead. shake, rotate (or tilt or roll)
Why is isotonicity important? Because the injectable solution needs to be isotonic with the blood.
Important characteristics of parenteral products are: acid content of the pH of the solution, and color and clarity of an IV
What should you do to detect particles in an IV bag? Hold the product in the light or a dark background
What is Total Parenteral Nutrition (TPN)? An IV nutritional solution
TPNs that contain lipid emulsions are not clear, therefore: precipitation cannot be seen
_____ is a protein source. Amino Acid
IVPB is the administration: of a second solution into an already established primary line
High concentrations of _______ is a carbohydrate source. dextrose
An IVPB must be hung ______ than the primary solution. higher
______ emulsions are a fat source. Lipid
Used to bathe or flush open wounds or body cavities. Irrigation
All items that have come in contact with antineoplastic agents must be disposed of in containers with the: biohazard symbol
What class cabinet is used in preparing antineoplastic agents? Class II
Which direction does the air go in Class II Biological Safety Cabinets? downward
If a vial is _________ with air, a spray or spill may occur when removing the needle. over pressurized
Hazardous waste container should be: removed from the work area and destroyed.
Why are antineoplastic agents a special concern? Because of their mutagenic and carcinogenic effects
The number of people working with antineoplastic agents should be: kept to a minimum
The Class II Biological Safety Cabinet should: be certified annually or any time the cabinet is moved, and the blower should be on at all times
Considerations in parenteral products include: Stability time, appropriate vehcile solution (compatibility), light protection
Why are antineoplastic agents a special concern? Because of their mutagenic and carcinogenic effects
The number of people working with antineoplastic agents should be: kept to a minimum
The Class II Biological Safety Cabinet should: be certified annually or any time the cabinet is moved, and the blower should be on at all times
Considerations in parenteral products include: Stability time, appropriate vehcile solution (compatibility), light protection
________ of a liquid is done by using a 0.22 micron filter. Sterilization
Parenteral Product Reference Materials include: Handbook on Injectables, Guide to Parenteral Admixtures
_______ of particulate matter is done by using a 5 micron filter. Filtration
What information does the parental references provide? Drug solution, compatibility, dosage, and dilution info
A non-government, non-profit organization designed to create standards on patient safety, healthcare information, and verification of products. United States Pharmacopeia
Purpose is to set standards for compounding to prevent harm and death to patients. USP 797
One route of exposure to hazardous drug is: inhalation
Sharps used in hazardous waste are disinfected in an: autoclave or microwave
The counters must be cleaned in a ________ motion. sweeping
CSP used for emergency situations Immediate Use CSPs
Personal Protective Equipement include: non-shedding gown, powder-free gloves, eye and face protection such as face shields
Sterilization methods include: dry heat, filtration, and steam
An example of Standard Operating Procedures (SOP) is: 70% isopropyl alcohol must be used to disinfect all additive containers
What determines the CSP risk level? compounding setting, contamination potential,
If Immediate Use CSP are not administered within ____ hour after preparation begins, it must be _______. one, thrown out
What are the different risk levels? Immediate Use, Low Risk, Low Risk with 12 hour or less BUD, medium risk, and high risk
Compounded using sterile drug and sterile devices, using aseptic techniques Low Risk Level CSP
Most of the risk level CSPs require ISO Class ___. 5
Administration must start within 12 hours or less after preparation Low Risk Level with 12-hour or less BUD
Uses complex aseptic technique, multiple small doses of sterile products are combined to create CSPs that will be given to several patients or one patient multiple times Medium Risk Level CSP
Uses non-sterile ingredients and devices High Risk Level CSPs
This vial contains a perservative Multi dose vial
This vial doesn't contain a perservative Single dose vial
destruction of all microbal life sterlization
destruction of pacific pathogenic microrganisms disinfection
Proper air quality is measured in: ISO
As ISO class goes up, so does that number of: particles allowed per cubic meter
Room where "hoods" are placed for compounding Buffer area
Used to ensure proper air quality, located between buffer area and common pharmacy Ante area
Volumetric air sampling is required: every 6 months
If a hazardous drug were to spill, what should the pharmacy technician do? use a spill kit
If the worker is containmated by a hazardous drug, what should be done? use eyewash kits and soap and seek medical attention
Hazardous waste should be disposed of in: an incinerator
Created by: Michelle Lee



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