Busy. Please wait.

show password
Forgot Password?

Don't have an account?  Sign up 

Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.

Remove Ads
Don't know
remaining cards
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
restart all cards

Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how


Key points, ADRs, review for Naplex/CPJE 2016

Cause kidney stones topiramate (Topamax) zonisamide (Zonegran) * drink plenty of water to reduce risk
sulfonamide anti-convulsant zonisamide (Zonegran) and topiramate (topamax)
Dose conversion between fosphenytoin and phenytoin Fosphenytoin 125-150mg = phenytoin 100mg
Free phenytoin level calculation for albumin < 4 measured conc / [(0.2 x albumin) + 0.1]
Free phenytoin level calculation for CrCl < 10 measured conc / [(0.2 x albumin) + 0.1]
Phenytoin therapeutic range 10-20mcg/mL > 20 mcg/mL = lateral nystagmus, > 30 ataxia, > 40 decreased mentation, > 100 death Free phenytoin level: 1-2.5
Phenytoin ADRs P-450 inducer Hirsutism Enlarged gums Nystagmus Yellow-browning of skin Teratogenecity Osteomalacia Interference with B12 metabolism (hence anemia) Neuropathies (verigo, ataxia, headache)
Autoinduction Carbamazepine (~ 21 days)
BBW of VPA hepatoxicity especially in children < 2 yo pancreatitis teratogenecity
BBW carbamazepine blood dyscrasias SJS (esp in asians + for HLA-B*1502)
Schedule of Fycompa (perampanel) C-III
Schedule of Phenobarb C-IV
Schedule of clobazam (Onfi) C-IV
Schedule of pregablin (Lyrica) C-V
Schedule of Lincosamide (Vimpat) C-V
Schedule of ezogabine (Potiga) C-V
Severe life-threatening rash esp when co-administered with VPA lamotrigine (Lamictal)
DOC for absence seizures ethosuximide (Zarontin)
Max IV rate for phenytoin 50mg/min
Phenytoin IV solution NS only due to propylene glycol
Oligohidrosis Zonisamide
Treatment of febrile seizures diazepam or lorazepam
Dose of Phenytoin for status epilepticus 15-20mg/kg LD 5-6 mg/kg/d divided TID (~300mg/d)
Created by: lukaszewiczj