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CNS Drugs
Question | Answer |
---|---|
Benzodiazepines do...?? | Release GABA to help sleep, decr. anxiety, prep, ETOH withdrawal |
What are the benzodiazepines? | Valium, Xanax, Ativan, Versed |
Adverse of benzodiazepines | over sedation, hangover, decr. respiration |
What is the reversal for benzodiazepines? | Romazicon |
Agents for sleep | Ambien, Lunesta, Benadryl, Rozerem, Sonata |
Skeletal muscle relaxants | Soma, Lioresal, Flexeril |
Soma, Liorsal, Flexeril | acute musculoskeletal pain, relieve spasm |
Adverse to Skeletal Muscle Relaxants | drowsiness, dizziness, N/V, flaccid muscles, dependence |
Dantrium | weaken muscle contraction for MALIGNANT HYPERTHERMIA, CP, OR STROKE |
Dilantin | stabilizes nerve membranes for all SEIZURES EXCEPT ABSENSE |
Adverse effect of dilantin | gingival hyperplasia |
Therapeutic range for Dilantin | 5-20 mcg/mL |
Who cannot use Dilantin | elderly and severe kidney/liver disease |
Klonopin | severe recurrent seizures |
Tegretol | SEIZURES |
Lamictal | SEIZURES |
Depakene | SEIZURES |
Topamax | SEIZURES |
Neruotin | SEIZURES |
Keppra | SEIZURES |
Luminal | SEIZURES limited use today |
Sinemet | increase dopamine for PARKINSON and RESTLESS LEG SYNDROME |
Adverse of Sinemet | early: "pill rolling", N/V, anorexia, orthoostatic hypotension, dizziness Late: involuntary movements, akinetic spells, anxiety, depression |
Who should not use Sinemet? | narrow angle glaucoma, melanoma, GI, heart disease |
What do you watch for with Sinemet? | darkening urine |
Artane and Cogentin | anticholinergic for EARLY PARKINSONS |
Who should not use artane and cogentin? | glaucoma, GI-GU obstruction, heart disease, elderly, young |
Symmetrel | Parkinsons |
Parlodel | Parkinsons |
Mirapex | Parkinsons |
Requip | Parkinsons |
Imitrex and Zomig | anti-migraine vasoconstict vessels in brain |
Adverse Imitrex and Zomig | nausea, HTN, dizziness, weakness |
Who cannot have Imitrex and Zomig? | CAD, HTN, do not give within 24h of ergot alkaloids |
Ergot alkaloids (Ergomar and Cafergot) | reduce extra cranial blood flow ANTI-MIGRAINE |
who should not take ergot alkaloids? | pregnant, severe HTN, CAD |
adverse effects of Ergot alkaloids | N/V, cramps, confusion, decreased circulation |
Vampiric acid | MIGRAINE |
Neurotin | MIGRAINE |
Topamax | MIGRAINE |
etomidate | IV ANESTHESIA |
propofol | IV ANESTHESIA |
Fentanyl citrate | IV ANESTHESIA |
ethrane | INHALANT ANESTHESIA |
nitrous oxide | INHALENT ANESTHESIA |
Tacrium | NEUROMUSCULAR BLOCK |
Norcuron | NEUROMUSCULAR BLOCK |
Anectine | NEUROMUSCULAR BLOCK |
Versed | CONSCIOUS SEDATION |
FENTANYL | CONSCIOUS SEDATION |
lidocaine | LOCAL ANESTHETIC |
Marcaine | LOCAL ANESTHETIC |
Adderall | ADHD, NARCOLEPSY, WEIGHT REDUCTION |
Ritalin | ADHD, NARCOLEPSY, WEIGHT REDUCTION |
Intuniv | ADHD, NARCOLEPSY, WEIGHT REDUCTION |
Strettera | ADHD, NARCOLEPSY, WEIGHT REDUCTION |
Adverse effects of ADHD meds | nervousness, irritability, HA |
Who should not take ADHD meds | anxiety, glaucoma, pregnant, HTN, dependence |
Phenothiazines | block dopamine receptors for SCHIZOPHRENIA, MANIA, PSYCHOTIC DEPRESSION |
Thorazine | Phenothiazine -- SCHIZOPHRENIA |
Prolixin | Phenothiazine -- SCHIZOPHRENIA |
Stelazine | Phenothiazine -- SCHIZOPHRENIA |
Adverse effects of phenothiazine | excessive sedation, slurred speech, impaired mental processes |
Nonphenothiazines | control symptoms of SCHIZOPHRENIA |
Haldol | nonphenothiazine control symptoms of SCHIZOPHRENIA |
Adverse of Haldol | seizures, decreased BP, EPS symptoms, EKG changes |
Clozaril | NEW SCHIZOPHRENIA |
Risperdal | NEW SCHIZOPHRENIA |
Zyprexa | NEW SCHIZOPHRENIA |
Who should not take Clozaril, Risperdal, Zyprexa | agranulocytosis, hyperglycemia, weight gain |
Eskalith | BIPOLAR |
Who should not use Eskalith? | cardiac/renal disease, hyponatremia, pregnancy, leukemia |
Therapeutic level for Eskalith | 0.6-1.2 |
Adverse for Eskalith | metallic taste, twitching, diarrhea, thirst |
What to look out for with Eskalith | Salt changes |
TCA antidepressants do...? | decrease serotonin and norepinephrine for DEPRESSION AND BED WETTING |
Adverse TCA antidepressants | sedation, orthostatic hypotension, decreased GI, dry mouth, cardiac arrhythmia, urinary retention |
TCA antidepressants: | Tofranil and Elavil |
SSRI do...? | increase serotonin for DEPRESSION, OCD, BULIMIA |
SSRI | Prozac, Celexa, Paxil, Zoloft |
SSRI adverse | anxiety, nausea, decreased appetite, weight loss, HA |
MAO | prevent metabolism of neurotransmitters |
Adverse of MAO | hypertensive with tyramine foods (cheese, beer, chocolate, yogurt, smoked meats) |
Zyban | DEPRESSION |
Effexor | DEPRESSION |
Cymbalta | DEPRESSION |
Remeron | DEPRESSION |