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Comp16-Anti-Infectiv
Competency 16
| Question | Answer |
|---|---|
| Anti-Infectives | drugs that can either kill an infectious agent or inhibit it from spreading. |
| Penicillins | Eliminate infection causing bacteria. they are bactericidal(to kill). |
| Examples of penicillin | Diclox(dicloxacillin), Pen Vee-K(penicillin V potassium), Ampicilin(ampicillin) |
| Cephslosporings | eliminate infection causing bacteria.Divided into generations |
| First Generation | Most active against gram-positive aerobes. Keflex(Cephalexin) |
| Second Generation | Improved activity over first generation. Cefotan(Cefotan, Mefoxin(cefoxitin) |
| Third generation | Active against serious gram negative infections. Cedax(ceftibuten), Vantin(Cefpodoxime), Suprax(cefixime). |
| Fourth Generation | Broad spectrum activity against both gram-negative and gram possitive. Maxipime (Cefepine) |
| Fifth Generation | Effective against methicillin resistant staphylocous aureus (MRSA). Teflaro (ceftaroline fosamil) |
| Monobactams | used to treat severe infections. Azactam(aztreonam) |
| Glycopeptide Antibiotics | Used to treat intestinal infections that cause colitis. Vanconin(vancomycin) |
| Aminoglycosides | Bactericidal and effective against both gram negative and gram positive microoganisms. Garamycin(gentamicin), Nebcin(tobramycin), Amikin(amikacin) |
| Macrolides | these drugs are effective against a wide range of microorganisms and are primarily bateriostatic. Biaxin(clarithronmycin), Zithromax(azithromycin). |
| Tetracylines | mainly bacteriostatic, but in high concentration can be bactericidal. Doxycyl(doxycycline), Minocin(minocycline), Sumycin(tetracycline) |
| Sulfonamides | Kill bacteria by interfering with bacterial synthesis. ex Ak sulf(Sulfacetamide) |