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rad bio ch 35
radiation biology ch 35 for midterm
| Question | Answer |
|---|---|
| what type of curve does erythema follow? | nonlinear, nonthreshhold |
| what are the most radiosensitive cells? | spermatogonia and lymphocytes |
| early effects of radiation are called: | deterministic |
| prodromal syndrome | acute clinical symptoms occuring within hours of exposure |
| hematologic symptoms | RBC, WBC, and platelets decrease in number |
| hematologic syndrome dose range | 200-1000 rad |
| hematologic syndrome recovery range | 2-4 weeks up to 6 months |
| gastrointestinal syndrome dose range | 1000-5000 rad |
| gastrointestinal syndrome recovery range | death in 4-10 days |
| CNS syndrome dose range | 5000 rad and above |
| CNS syndrome recovery range | death within hours to three days |
| what does the "50" represent in LD50/30? | percent of subjects irradiated |
| what does the "30" represent in LD50/30? | number of days in which death will occur |
| LD50/30 | dose of radiation to the whole body that will result in death within 30 days to 50% of the subjects irradiated |
| what type of curve does erythema follow? | nonlinear |
| SED50 | affects 50% of people exposed at 500 rad |
| a single dose of how many rad will cause mild erythema? | 300-1000 rad |
| what effect does 10 rad to the gonads have on the female? | delay of menstruation |
| what effect does 10 rad to the gonads have on the male? | reduction in spermatozoa |
| what effect does 200 rad to the gonads have on the female? | temporary sterility |
| what effect does 200 rad to the gonads have on the male? | temporary infertility |
| what effect does 500 rad to the gonads have on the female? | permanent sterility |
| what effect does 500 rad to the gonads have on the male? | permanent sterility |
| how long should a male wait for procreation after 10 rad to the gonads? | 2-4 months |
| how long should a female wait for procreation after 10 rad to the gonads? | several months |
| what type of curve do radiation induced chromosome aberrations follow? | nonthreshhold |
| can aberrations be observed at 5 rad? | not well |
| how many autosomes does each cell have? | 22 plus a pair of sex chromosomes |
| which type of hit is more likely at low radiation levels? | single hit |
| when might a single hit take place? | during G1 or G2 |
| what is most likely to occur following a single hit during G1 or G2? | damage of one chromatid |
| what type of aberrations might occur with a multi-hit | ring, dicentric, reciprocal translocation |
| at what dose do multi-hit aberrations occur more? | 100 rad |
| what type of curve does multi-hit aberrations follow? | nonlinear, nonthreshhold |
| what type of curve do single hit aberrations follow? | linear nonthreshhold |
| pluripotent stem cell | base stem cell which can turn into a lymphocyte, granulocyte, thrombocyte, or eurethrocyte |
Created by:
annaluz87
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