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Adrenergic Pharmaco2
Adrenergic Pharmacology - Clinical uses
| Treatment of... | Drugs | Which Rs should be ACTIVATED? | Which Rs should be BLOCKED? |
|---|---|---|---|
| Hypertension | Methyldopa, Clonidine (alpha 2 ag); Prazosin, Terazosin, Doxazosin (alpha 1 antag); Phentolamine, Phenoxybenzamine (alpha NS antag); Guanethidine (adrenergic neuron blocker) | alpha-2 and/or beta-2 | alpha-1 |
| Urinary symptoms in BPH | Prazosin, Terazosin, Doxazosin | none | alpha-1 |
| Hypertension in patients with pheochromocytoma (catecholamine excess) | Phentolamine, phenoxybenzamine | none | alpha-1 and alpha-2 |
| ADHD, obesity, fatigue, narcolepsy | Amphetamine | N/A - potentiate effects of NE | none |
| poor renal perfusion; shock; CHF, hypotension | Dopamine | D1, increase production and release of NE | none |