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Antacids
antacids
| Question | Answer |
|---|---|
| name the non-systemic antacids... | calcium, aluminum, and magnesium-based |
| name systemic antacid | Sodium-based |
| MOA of antacids | chemically combine the H+ ions (to water, CO2, etc.) and increase LES tone------do NOT decrease acid secretion |
| Magaldrate is a combo of what antacids? | magnesium and aluminum (converted to individual compound in presence of gastric acid) |
| What is Simethicone? | a surfactant that deceases surface tension (PRO-FART) |
| what is Alginic acid? | "inactive" bubbles on top of gastric contents and protects esophagus with reflux |
| Aluminum-based ADR | constipation, renal problems, hypernatremia |
| Magnesium-based ADR | diarrhea, hypermagnesemia |
| Calcium-based ADR | constipation, hypercalcemia, kidney stones |
| Sodium-based ADR | GAS, hypernatremia, metabolic alkalosis |
| What antacids are hypernatremic? | aluminum and sodium-based |
| when to take antacids with other drugs (LOTS OF INTERACTIONS) | 1-2 hours before or..... 2-4 hours after |
| what is the weakest non-systemic antacid? | aluminum |