Save
Busy. Please wait.
Log in using Clever
or

show password
Forgot Password?

Don't have an account?  Sign up 
Sign up using Clever
or

Username is available taken
show password

why


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.


Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't know
Remaining cards (0)
Know
0:00
share
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Pharmacology

Valdeny Article

QuestionAnswer
Liver size and blood flow decreases with age by __ to ___% 17-46
The CYP system metabolizes over ______ of all drugs? half
Why are older adults at higher risk for CYP450-related drug interactions and adverse effects? because of polypharmacy
The CYP3A4 isozyme decline by approximately ___% annualy. 8
Why is the decline of the CYP3A4 isozyme clinically relevant? Because more than 50% of drugs metabolized by the CYP system require the CYP3A4 isozyme.
Renal function declines by __ to __% with age. 35-50
Creatinine clearance in older adults id a good measure for what? glomerular filtration rate
T or F. For older adults lower doses of opioids are recommended. True
Acetaminophen increases hepatic toxicity if the total amount exceeds_________. 4 grams in 24 hours
Antihistamines, antipsychotics, antidepressants, antihypertensives, anticonvulsants, and opiods are considered to be _____ depressants. CNS
What is the most common hypnotic used by older adults? benzodiazepine
Acutely benzodiazepines can cause what? anterograde amnesia, delirium, paradoxical agitation
Chronic use of benzodiazapine can result in what? falls and resultant fractures
the most prevalent form of drug induced osteoporosis is caused by which drug? glucocorticoids
The elderly make up ___% of the population yet consume ____ of prescription meds and over _____ of OTC meds. 12, one third, half
In elderly patients, are the effects of drugs longer or shorter in duration and why? longer due to the decrease in hepatic and renal function
In elderly patients, are the effects of drugs more or less dramatic? more
Created by: txst spr 2009
 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!

"Know" box contains:
Time elapsed:
Retries:
restart all cards