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symptoms of vulvovaginal candidiasis
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vulvovaginal bug
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symptoms of vulvovaginal candidiasis itching sore, irriating, burning w/ urination, cheese like discharge, gram stain similar to UTI
vulvovaginal bug candida albicans
risk factors for vulvovaginal candidiasis oral genital contact, initial sex (diaphram or spermicide use), abx use, douching, tight cloths
vulvovaginal candidiasis pharm therapy...uncomplicated uncomplicated (OTC): butoconazole (3 days), clotrimazole (1-7 days), miconazole (1-7 days), ticonazole (1 day).....uncomplicated RX: econazole (1tab), nystatin (14days), terconazole 1-7 days
treat systmeically vulvovaginal candidiasis Fluc (150), itra 200 twice
are oral and topical therapies equivalent for azoles? yes
what makes a vulvovaginal candid complicated? C glabrata, immunocompromised, DM, pregnant, recurrent more than 4 epi/year, severe symp
how should itra be taken? with acidic drink
signs and symp of oropharyngeal candid could have pain, white thick plaques around mouth, burning or pain, taste changes
what is the bug for oropharyngeal candid? C albicans....but 30-60% are colonized
what are the 3 categories of risk factors for oropharyngeal condid? disease related (DM, immunodiff (aids), hypothyroid, adrenal disfunction.....med related (immunosuppressants, radiation, dentures, broad spec abx)....gen conditions (premature, elderly, malnutrition, newborns
how to treat oropharyngeal candid..ROUTE? topical preferred, clotrimazole troche (4-5 times/day for 7-14 days)...nystatin susp, fluc tabl, itra susp
how to treat esophageal? fluc 14-21 days (preffered), itra 14-21 days, imporve in 2-3 days, resolve in 7-10 days
name the 3 dermatophytic infections? jock itch, ringworm, athletes foot
treat of dermatophytic? clotrimazole cream, econazole cream, ketoconazole cream, miconazole cream, nystatin cream, terbinafine cream, tolnaftate cream
how to treat toenail and fingernail infxn oral therapy..monitor LFT's....terbinafine (fingernails: 6 weeks, toenails 3-4 months), itraconazole: fingernailes 200mg /2months 1 week, toenails 3-4 months)
invasive candidiasis risk factors (lots) any cath/lines....GI procedure or mech ventilation....DM, Solid tumor, CV....immunosuppression, chemo, ICU, pancreatitis, TPN, corticosteroid administration
what to do if fungal infection suspected systemically?? TREAT IMMEDIATELY....fluc for albicans...know susceptibility
what are the most common bugs for invasive candidiasis and other bugs? albicans, krusei, glabrata
what are the key patient and institutional charactoristics for antifungal therapy? (3) common fungal species in your area, patient underlying conditions abx steroid use and length of ICU stay...other fungal risks
what is onychomycosis? fungal infection of the nails
why is onychomycosis usually treated? cosmetic reasons, sometimes pain
how to treat onychomycosis?route? ORAL only, terbinafine (fn: 6 weeks, tn: 3-4 months), itraconazole (fn: 2months 1 wk, tn: 3-4 monts)
treat candiduria? ampho B, fluc
what drug to not use in candiduria echinocandins
when would you treat candiduria? if cath is positive (pull then retest), if high risk for systemic disease (renal transplant, obstruction, immunocompromised)
echinocandins (3) micafubgin, capsofungin, anidulafungin
echinocandins moa
do drug activity ones again
Created by: tayl1336
 

 



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