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Stack #208071

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
symptoms of vulvovaginal candidiasis   itching sore, irriating, burning w/ urination, cheese like discharge, gram stain similar to UTI  
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vulvovaginal bug   candida albicans  
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risk factors for vulvovaginal candidiasis   oral genital contact, initial sex (diaphram or spermicide use), abx use, douching, tight cloths  
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vulvovaginal candidiasis pharm therapy...uncomplicated   uncomplicated (OTC): butoconazole (3 days), clotrimazole (1-7 days), miconazole (1-7 days), ticonazole (1 day).....uncomplicated RX: econazole (1tab), nystatin (14days), terconazole 1-7 days  
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treat systmeically vulvovaginal candidiasis   Fluc (150), itra 200 twice  
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are oral and topical therapies equivalent for azoles?   yes  
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what makes a vulvovaginal candid complicated?   C glabrata, immunocompromised, DM, pregnant, recurrent more than 4 epi/year, severe symp  
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how should itra be taken?   with acidic drink  
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signs and symp of oropharyngeal candid   could have pain, white thick plaques around mouth, burning or pain, taste changes  
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what is the bug for oropharyngeal candid?   C albicans....but 30-60% are colonized  
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what are the 3 categories of risk factors for oropharyngeal condid?   disease related (DM, immunodiff (aids), hypothyroid, adrenal disfunction.....med related (immunosuppressants, radiation, dentures, broad spec abx)....gen conditions (premature, elderly, malnutrition, newborns  
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how to treat oropharyngeal candid..ROUTE?   topical preferred, clotrimazole troche (4-5 times/day for 7-14 days)...nystatin susp, fluc tabl, itra susp  
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how to treat esophageal?   fluc 14-21 days (preffered), itra 14-21 days, imporve in 2-3 days, resolve in 7-10 days  
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name the 3 dermatophytic infections?   jock itch, ringworm, athletes foot  
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treat of dermatophytic?   clotrimazole cream, econazole cream, ketoconazole cream, miconazole cream, nystatin cream, terbinafine cream, tolnaftate cream  
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how to treat toenail and fingernail infxn   oral therapy..monitor LFT's....terbinafine (fingernails: 6 weeks, toenails 3-4 months), itraconazole: fingernailes 200mg /2months 1 week, toenails 3-4 months)  
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invasive candidiasis risk factors (lots)   any cath/lines....GI procedure or mech ventilation....DM, Solid tumor, CV....immunosuppression, chemo, ICU, pancreatitis, TPN, corticosteroid administration  
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what to do if fungal infection suspected systemically??   TREAT IMMEDIATELY....fluc for albicans...know susceptibility  
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what are the most common bugs for invasive candidiasis and other bugs?   albicans, krusei, glabrata  
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what are the key patient and institutional charactoristics for antifungal therapy? (3)   common fungal species in your area, patient underlying conditions abx steroid use and length of ICU stay...other fungal risks  
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what is onychomycosis?   fungal infection of the nails  
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why is onychomycosis usually treated?   cosmetic reasons, sometimes pain  
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how to treat onychomycosis?route?   ORAL only, terbinafine (fn: 6 weeks, tn: 3-4 months), itraconazole (fn: 2months 1 wk, tn: 3-4 monts)  
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treat candiduria?   ampho B, fluc  
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what drug to not use in candiduria   echinocandins  
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when would you treat candiduria?   if cath is positive (pull then retest), if high risk for systemic disease (renal transplant, obstruction, immunocompromised)  
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echinocandins (3)   micafubgin, capsofungin, anidulafungin  
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echinocandins moa    
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do drug activity ones again    
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Created by: tayl1336