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rad bio ch 33
radiation biology quiz 1 ch 33
| Question | Answer |
|---|---|
| Law of Bergonie and Tribondeau | measures the radiosensitivity of cells |
| How are oxygen and radiosensitivity related? | higher oxygenation means more free radicals resulting in radiosensitive cells. |
| How are cell growth and radiosensitivity related? | increased proliferation means increased radiosensitivity |
| LET | linear energy transfer – rate at which energy is transferred from ionizing radiation to tissue |
| RBE | relative biologic effectiveness – amount of biologic damage caused by radiation |
| How are LET and RBE related? | increased LET means increased RBE |
| Wr | radiation weighting factor – amount of energy deposited varies based on the type of radiation used. |
| Wt | tissue weighting factor – radiosensitivity will vary based on the type of tissue |
| Effective dose formula | Wr X Wt X absorbed dose |
| Protraction | a constant dose over a long period of time with a low exposure rate |
| Fractionation | dose delivered in fractions over a long period of time |
| OER | oxygen enhancement ratio – amount of dose needed to produce a given effect over the amount needed for the same effect in higher oxygen situations |
| How are LET and OER related? | OER is higher with low LET |
| Threshold curve | begins on the X or Y axis |
| Nonthreshhold curve | begins at zero |
| Nonlinear curve | sigmoid |
| What type of response is expected with a linear threshold curve? | none |
| What effects are seen with nonlinear threshold curves? | skin effects, erythema and radiation induced death |
| What response is expected with a nonlinear nonthreshhold curve? | large response with low dose |
| What effects are seen with a linear nonthreshhold curve? | radiation induced cancers, genetic effects, leukemia |
| Which curve is used for radiation protection guidelines? | linear nonthreshhold |
| What does the X axis represent for radiation curves? | dose |
| What does the Y axis represent for radiation curves? | response |
| Roentgen | radiation exposure in air |
| RAD | radiation absorbed dose – dose absorbed by the patient |
| REM | radiation equivalent man – occupational exposure (millirem) |
| How are RBE, OER and weight related? | inc. RBE, inc. weight means inc. damage and dec. OER |
Created by:
annaluz87
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