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Acute Corinary Syndrome

Drug NameClassWho gets it?
eptifibatide (intergrilin) Glycoprotein IIb/IIIc receptor antagonists (antiplatelet agent) renal cleared IV during PCI and 12-24 hours afterward
tirofiban (aggrestat) Glycoprotein IIb/IIIc receptor antagonists (antiplatelet agent) renal cleared IV during PCI and 12-24 hours afterward. AE bleeding thrombocytopenia monitor hematocrit and platelet counts
UFH antithrombin agent for 48 hours
Enoxaparin antithrombin agent not renal failure or dialysis BID daily preferred (or fond) in low risk and being treated with conservative medical strategy
bivalirudin antithrombin agent direct thrombin inhbitor preferred agent if HIT present or suspected. doesn't require the use of Gpp IIb/IIIa receptor during PCI if this is used. not used in conservative treatment. reduced risk of bleeding compared to LMWH and UFH. can be continued for duration of stay
fondaparinux antithrombin agent not in CrCL <30 mL/min. not recommended at time of PCI because will need another agent. preferred with enox, in low risk and being treated with conservative medical strategy
oxygen lower than 80
aspirin 325
morphine those with refractory angina as analgesic and venodilator that lowers preload
IV metoprolol avoid IV when at risk for shock beta blocker decrease rate and oxygen demand, get it if don't show evidence of acutely low out put, no peripheral edema, JVD, rales of S3 heart sounds. give oral if SPB not >160
streptokinase (streptase) thrombolytic potential antigenicity, Ci with prior exposure greater than 5 days
anistrepalse (aminase) thrombolytic potential antigenicity, CI with prior exposure greater than 5 days
alteplase (activase) thrombolytic
reteplase (retavse) thrombolytic genetically modified plasminogen activator similar to t-PA with longer half life
tenecteplase (TNK) thrombolytic high fibrin specificity longer half life and higher resistance to inhinbition by plasminogen activator inhibitor
urokinase non popular thrombolytic
abciximab (reoPro) Glycoprotein IIb/IIIc receptor antagonists (antiplatelet agent)
Created by: lainylaina
Popular Pharmacology sets




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