Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Pharmacology
Theory nitrates
| Question | Answer |
|---|---|
| All nitrates are known collectively as | Nitrovasodilators |
| All nitrates lead to the formation of what chemical? | Nitric oxide |
| Pharmacological what effect do nitrates have on the body | Venous and arterial dilation: Dilation of veins predominates over that of arteriolar. As a result, a decrease in left and right ventricular EDP(preload) and a smaller decrease in systemic arterial pressure(after load). |
| Venous and arterial dilation causes what in the heart | Decreasing myocardial workload and oxygen demand |
| The realize of NO can cause e activation of what chemical | Cyclic GMP (cGMP) |
| cGMP causes vasodilation by | Decreasing calcium levels in the cell |
| What are are anti-anginals used for | Treatment and prevention if angina pectoris |
| What are some side effects of nitroglycerin | Hypotension, headache,dizziness,tachycardia,flushing |
| How is sublingual nitroglycerin administered | 1 tablet every 5 mins until, pain subsides or significant drop in BP. No more than 4-5 tabs if still in pain call i911 |
| What is nitric oxide and what is it do | Free radical, inducescoronary vasodilation |
| How do nitrates cause a reduction in venous return (preload) | increasing the venous capacitance causing pooling of blood in peripheral veins in there there by a reduction in venous return and ventricular volume |
| True or false nitrates are better arterial then Venus dilators | False |
| What is the gold standard of acute angina | Sublingual nitroglycerin |
| To decrease the notorious nitrate tolerance, an"on/off strategy of at least ____ -______ nitrate-free interval" is practiced | 10-hour |
| Intra-coronary NTG is used to minimize ischemia I do to coronary spasm true or false | True |
| How does NTG relieve angina | It increases oxygen supply to the heart muscle |
| The body relaxes vascular smooth muscle in that in arterial walls by releasing its own supply of | Nitric oxide |
| Nitro paste is administered in what units of measure | Inches |
| IV NTG is stored in class rather than plastic because | NTG is in activated by polyvinylchloride plastic |
| Nitroglycerin would be contraindicated in | Severe hypotension |
| Nitrates cause vasodilation by | Relaxing vascular smooth muscle |
| Overdosage of sodium nitroprusside can result in cyanide poisoning the reversal agent for this Toxicity | Methylene blue |
| The mechanism of nitroglycerin's effect on vascular smooth muscle is | Preventing calcium from initiating actin and myosin and coupling |
| Reducing preload and afterload a reduces angina on by | Decreasing myocardial oxygen demand |
| The usual sub lingual does a nitroglycerin | 0.4 mg |
| nitroglycerin sublingual tablets should not be chewed because of reduction in potency caused by | First pass metabolism |
Created by:
Ashleyzdanowicz18
Popular Pharmacology sets