click below
click below
Normal Size Small Size show me how
Pharm term 2
Beta Blockers
| Question | Answer |
|---|---|
| What are beta blockers also known as? | Beta adrenergic blocking agents |
| Where are beta 1 receptors located? | In the heart |
| Where are beta 2 receptors found? | In the lungs |
| How do beta blockers work? | By blocking the effects of norepinephrine and epinephrine they reduce heart rate, reduce blood pressure by dilating blood vessels |
| How do non selective beta blockers work? ( propranolol /inderal) | l black b1 and b2 receptors therefore affect the heart, blood vessels and air passages |
| How do selective beta blockers work? Metoprolol, lopressor | Primarily block B 1 receptors and therefore mostly affect the heart and do not affect air passages |
| How does Labetalol /normadyne and Carvedilol/ coreg work? | They block beta and alpha 1 receptors. Blocking alpha receptors adds to the blood vessel dilating effect of labetalol and carvedilol |
| What is a side effect of beta blockers that block B 2 receptors? | They may cause shortness of breath in asthmatics. |
| What is the beta that beta blockers block? | Beta adrenergic receptors of the SNS |
| Which condition might be an indication for beta-blockade? | BP 190 / 101 |
| For what purpose are cardiac patients often prescribed beta blockers? | anti aginal |
| A patient on lopressor complains of fatigue and slow heart rate. What do you suspect? | Normal effect of beta-blockade |
| To reduce myocardial oxygen consumption, angina pectoris patients sometimes take: | Lopressor |
| Fatigue and slow heart rates often occur with administration of: | Beta blockers |
| What letters do beta blockers tend to end in? | Lol |
| The generic name for inderal is: | Propranolol |
| The following pathology is a relative contraindication for administering certain beta antagonist: | Status asthmaticus |
| What drug when used in therapeutic doses, intentionally depresses the pumping action of the heart? | Propranolol |
| Patients receiving beta-blockers will have | Increased R-R interval |
| Loss of effectiveness of beta-blockade over a long period of time may be due to: | Receptor up-regulation |
| Beta blockers ultimately reduce the coupling of actin and myosin fibrils by their effect on the chemical | Troponin I |
| Increase in the number of beta receptors present on cell membranes in response to sustained beta-blockade is known as: | Upregulation |
| Beta blockers reduce oxygen demand by decreasing the double product which isv | Heart rate times blood pressure |
| Beta blocker dosage is adjusted to attain a resting heart rate ofv | 55 to 60 beats per minute |
| Post-infarction, administration of beta blockers | Reduces mortality 35% |
| Effects of beta blockers include | Decreasing cardiac muscle contractility |
| Which of the following is an indication for beta blocker therapy? | Prevention or treatment of an MI |
| Timolol is a non-selective beta antagonist. Therefore its use is contraindicated in patients with: | Asthma |
| Which of the following statements best describes one of the mechanism of action of beta adrenergic blocking agents? | The inhibition of the reaction between norepinephrine and the receptor. |
| Metoprolol tartrate is used as an: | Anti hypertensive |
| Labetalol/normodyne would not be used to treat: | Asystole |
| Labetalol/normodyne may be used to treat: | Hypertension, angina, symptomatic mitral valve prolapse, sinus tachycardia caused by hyperthyroidism |