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Unit 4 Heart

Medications affecting Blood Pressure

QuestionAnswer
ACE Inhibitors (Pg. 249); what do the generic names end with? Pril's, Ex. Captopril (Capoten)
What does ACE stand for? Angiotensin-converting enzyme (ACE) inhibitors
What do ACE inhibitors do? Block angiotensin 1 from converting to angiotensin 2
How do ACE affect the body? Vasodilation, excretion of sodium/water, retention of potassium
Common s/e of ACE; Orthostatic hypotension, cough, hyperkalemia
Captopril s/e that can occur: Rash & dysgeusia (altered taste) & neutropenia
ARB's (Pg. 252); what do the generic names end with? Sartan's; Ex. Losartan (Cozaar)
What does ARB stand for? Angiotensin 2 receptor blockers
How do ARBs affect the body? Vasodilation, excretion of sodium/water, retention of potassium
Major difference between ACE & ARB's? No cough/hyperkalemia w/ ARBs
Aldosterone Antagonists (Pg. 253); what are the 2 meds? Eplerenone (Inspra), spironolactone (aldactone)
How to remember the 2 meds for AA: We will SE you at AA
How do AA's affect the body? Excrete sodium & water
S/e of AA's Hyperkalemia, hyponatremia, flulike s/s
Direct Renin Inhibitors (Pg. 254): What is the one med? Aliskiren (Tekturna)
How to remember DRI's: DIRECT need A - listereen strip
Calcium Channel Blockers: (Pg. 255); what are the meds? 4 Pine's (FANN) & VD (verapamil, diltiazem)
What do CCB's do? Block calcium channels in BV's, lead to vasodilation of peripheral arterioles & arteries/ioles of the heart
See page 257 for s/e of CCB's
Created by: mary.scott260!
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