Busy. Please wait.
or

show password
Forgot Password?

Don't have an account?  Sign up 
or

Username is available taken
show password

why


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.


Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.

Remove Ads
Don't know
Know
remaining cards
Save
0:01
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
Retries:
restart all cards




share
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

GERD/PUD

Important Info

QuestionAnswer
Alarm symptoms for GERD GI bleeding, black stools, vomiting blood
What is Zollinger-Ellison? How do you treat? hypersecretion of acid by a tumor. Give PPI BID
Definition of peptic ulcer disease and causes mucosal erosions. May be due to H. pylori, aspirin, NSAIDs, corticosteroids
Antacids that are renally cleared (AVOID in renal dysfunction) Aluminum (AlOH3) and Magnesium (MgOH2)
Antacid to Avoid in Pregnancy Sodium containing! (can cause fluid overload/metabolic alkalosis) NaHCO3 (Sodium Bicarbonate). Also avoid in HTN and CHF
Major side effects of Aluminum containing antacids Constipation, Aluminum intoxication(renal)
Major side effect of Calcium containing antacids Constipation (Calcium=Constipation)**
Major side effect of Magnesium containing antacids Diarrhea! (Remember, Mag Citrate treats constipation...)
3 Major drug interactions with antacids Antibiotics: Tetracyclines(chelate), Quinolones Levothyroxine Things that need acidic environment: Iron, Ketoconazole, itraconazole
Gaviscon Alginic Acid
Alginic Acid MOA Floats on top of the stomach to protect the esophageal mucosa... therefore requires an upright position (no impact on nocturnal GERD)
H2RAs = All are Pregnancy Category ___ B
Tagament Cimetidine
Zantac Ranitidine
Pepcid Famotidine
Axid Nizatidine
Cimetidine (Tagament) - unique side effects; Drug interactions, max dose SE: gynecomastia, galactorrhea; CYP1A2 Inhibitor (increases warfarin/theophylline), MDD=800 mg
Ranitidine(Zantac) - DOC for..., max dose DOC in pregnancy, MDD=300 mg
Famotidine (Pepcid) - Max dose MDD=40mg
Nizatidine (Axid) - unique point, Max dose Unique: only one not available IV/IM, MDD= 300 mg
H2RA dose comparison Cimetidine 400=famotidine 20 = Nizatidine 150=Ranitidine 150
H2RA Class effects CNS (dizzy, sedation, confusion, can worsen dementia), all pregnancy category B, Dose adjust for renal dysfunction!!!! <50 ml/min for most (<30 ml/min for cimetidine)
PPI MOA Irreversibly block H+/K+ ATPase in the gastric parietal cells
PPI Administration time and reason 30 minutes before breakfast - because your body starts making proton pumps in the morning, drug is then onboard to work when they become active with eating
Prilosec omeprazole
Zegerid omeprazole/sodium bicarb
Nexium esomeprazole
Vimovo Esomeprazole/naproxen
Prevacid Lansoprazole
Dexilant Dexlansoprazole
Protonix Pantoprazole
Created by: naplexreviewgirl