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nonsteriod antiasthm
| Question | Answer |
|---|---|
| is used as a prophylactic Tx | non-steroidal anti-asthmatic agents |
| nonsteriodal antiasthmatic agents are _ cell _ | mast cell stablizer |
| it may inhibit mediator release by preventing __ necessary 4 micro-filament contraction & extrusion of mast cells | calcium influx |
| prophylactic Tx inhibits the release of | histamine from the mast cells |
| indicated as prophylactic therapy in Mang. of mild persistent asthma (CONTROLLER only) dose 20mg QID; seasonal allergies 1wk be4 allergen; 30min be4 certain allergens; 15min be4 exercise VERY safe drug | cromolyn sodium (intal/0 |
| SE if any at all of Intal (cromolyn sodium) | nasal congestion cough hoarseness |
| these are messengers utilized between cells during the inflammation process 2 help control it | leukotrines |
| w/ these inhibitors watch liver enzymes cuz it may cause hepatoxicity oral= tablets | leukotriene inhibitors |
| leukotriene inhibitor drug examples | zafirllukast (accolate) montelukast (ingular) Zileuton (zyflo) |
| omalizumab (Xolair) is under what class | monoclonal antibody |
| these bind to IgE & block its binding to the receptor site of mast cells & basophils S.C injection Q4 weeks dose determined by Pt WT & IgE serum | monoclonal antibody drug omalizumab (Xolair) |