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Top 200 #9

ClassBrandGenericIndicationDose FormRouteAdult DosePed DoseMOA
Biphasic Contraceptive Combo (Estrogen and Progestin) Kariva; Mircette; Ortho Novum 10/11 Biphasic Contraceptive Combo Contraception Varies Oral 1 tab QD, same time each day Safety & efficacy before menarche have not been established “see mono”
Triphasic Contraceptive Combo (Estrogen and Progestin) Ortho Tri-Cyclen; Ortho Tri-Cyclen Lo; Tri-Sprintec; Trivora Triphasic Contraceptive Combo Contraception Varies Oral 1 tab QD, same time each day Safety & efficacy before menarche have not been established “see mono”
Contraceptive; Endocrine-Metabolic Agent; Progestin Nor-QD; Micronor; Camila Norethindrone Contraception Oral Tablet: 0.35mg Oral 1 tab QD, same time each day Safety & efficacy before menarche have not been established Prevents ovulation, inhibits sperm penetration by thickening the cervical mucus, reduces midcycle luteinizing hormone & follicle-stimulating hormone peaks, delays the movement of ovum through the fallopian tube and alters the endometrium lining
Contraceptive Estrogen and Progestin Combo NuvaRing Ethinyl Estradiol/ Etonogestrel Contraception Vaginal Insert (ER): 0.015mg-0.12mg/24hr Vaginally Insert 1 ring and wear continuously for 3 weeks, remove for 1 week and repeat with a new ring Safety & efficacy before menarche have not been established Suppresses gonadotropins; inhibits ovulation; changes cervical mucus and the endometrium
Antineoplastic Agnet; Contraceptive; Progestin; Endocrine-Metabolic Agent Provera Medroxyprogesterone Abnormal uterine bleeding unrelated to menstrual cycle; contraception; endometrial hyperplasia; endometriosis; 2® physiologic amenorrhea Oral Tablet: 2.5, 5, 10mg; SubQ Susp: 104mg/0.65ml IM Susp: 150mg/ml, 400mg/ml; IM, Oral, SubQ Tablets: dosing varies; IM injection: done once every 3 months N/A Has androgenic & anabolic effects; transforms proliferative into secretory endometrium in women with adequate endogenous estrogen
Endocrine-Metabolic Agent; Estrogen; Female Reproductive Agent Premarin Estrogens (conjugated) Abnormal vasomotor function, dyspareunia – menopause; atrophic vulva; carcinoma of prostate; decreased estrogen level; dysfunctional uterine bleeding; metastatic breast cancer IV Powder for Soln: 25mg; Oral Tablet: 0.3, 0.45, 0.625, 0.9, 1.25mg; Vaginal Cream: 0.625mg/gm IV, Oral, Vaginally Varies N/A (however, estrogen therapy has been used for induction of puberty) Binds to nuclear receptors in estrogen-responsive tissues; modulates the pituitary secretion of the gonadotropins, LH, FSH, through a negative feedback mechanism, reducing the levels of these hormones seen in postmenopausal women
Endocrine Metabolic Agent; Selective Estrogen Receptor Momdulator Evista Raloxifene Breast Cancer, Osteoporosis Oral Tablet: 60mg Oral 60mg QD N/A (SERM) selectively activates and blocks estrogenic paths by binding to specific estrogen receptors
Nutriceutical; Nutritive Agent; Vitamin B Folic Acid Folic Acid Megaloblastic Anemia,folic acid deficiency Inj. Soln: 5mg/ml;cap:5mg,2000mcg Oral Tablet: 0.4mg, 0.8mg, 1mg, 800mcg Oral, SubQ, IV, IM Deficiency:0.4-0.8mg/day; homocystinemia:0.5-5mg/day; Pregnancy prophylaxis:0.4-1mg/day Deficiency;megaloblastic anemia :infants 0.1mg/d;<4yo 0.3mg/d;>4yo 0.4mg/d After conversion to tetrahydrofolic acid, it’s necessary for erythropoiesis, synthesis of purine and thymidylates, metabolism of amino acids (gly. and met. and the metabolism of histidine
Antimuscarinic; Urinary Antispasmodic Detrol; Detrol LA Tolterodine Overactive Bladder Oral Tablet: 1, 2 mg; ER Capsule: 2, 4 mg Oral IR Tablet: Initial= 2mg BID, may lower dose to 1mg BID; ER Tablet: Initial= 4mg QD, may lower dose to 2mg QD N/A Competitive muscarinic receptor antagonist, mediating contraction of the urinary bladder and enhances salivation
Antimuscarinic; Urinary Antispasmodic Vesicare Solifenacin Overactive Bladder Oral Tablet: 5, 10mg Oral 5-10mg QD N/A Exerts competitive antagonists effects at the muscarinic receptor
Αlpha-1 Blocker; Benign Prostatic Hypertrophy Agent Flomax Tamsulosin Benign prostatic hyperplasia Oral Capsule: 0.4mg Oral Initial = 0.4mg QD, if no response after 2 to 4 weeks, may increase to 0.8mg QD Take 30min after same meal QD N/A Alpha-1 antagonist, selectively blocks sympathetic nervous stimulation of the receptor  relaxation of the smooth muscles of prostate, prostatic urethra and bladder neck for improvement in urine flow rate
Anti-hypertensive; Erectile Dysfunction Agent; PDE5 Inhibitor Cialis Tadalafil Erectile Dysfunction Benign prostatic hyperplasia; Pulmonary HTN Oral Tablet: 2.5, 5, 10, 20mg Oral Varies ED: 2.5mg QD or 10mg 30min prior to sexual activity BPH: 5mg QD N/A PDE5 inhibitor
Anti-hypertensive; Erectile Dysfunction Agent; PDE5 Inhibitor; Vasodilator Viagra Sildenafil Erectile dysfunction; Pulmonary HTN (Revatio only) Oral Tablet: 25, 50, 100mg (Another brand name = Revatio, available in IV Soln. 10mg/12.5ml) Oral 25-100mg (50mg is usual dose) 1 hour prior to sexual activity; max of 1 dose per day N/A Inhibitor of cGMP specific PDE5 in smooth muscle where PDE5 is responsible for degradation of cGMP
Bisphosphonate; Ca2+ Regulator Actonel; Atelvia Risedronate Osteoporosis; Paget’s disease; postmenopausal osteoporosis Oral Tablet: 5, 30, 35, 150mg; Delayed Release Tablet: (Atelvia) 35mg Oral Varies N/A Binds to bone hydroxyapatite, and at the cellular level, inhibits osteoclast activity, thereby modulating bone metabolism
Bisphosphonate; Ca2+ Regulator Boniva Ibandronate Postmenopausal osteoporosis Oral Tablet: 150mg; IV Soln: 1mg/ml Oral, IV 2.5mg QD or 150mg once a month; IV: 3mg infused over 15-30 seconds every 3 months N/A Inhibits osteoclast-mediated bone resorption and turnover leading to a net gain in bone mass
Bisphosphonate; Ca2+ Regulator Fosamax Alendronate Osteoporosis; Paget’s disease; postmenopausal osteoporosis Oral Soln: 70mg/75ml; Oral Tablet: 5, 10, 35, 40, 70mg; Effervescent Tab: 70mg Oral Typically 70mg once a week N/A Binds to bone hydroxyapatite and inhibits osteoclast-mediated bone resorption
Androgen; Endocrine-Metabolic Agent Androderm (Patch); AndroGel (Gel); Delatestryl (IM); Depo-Testosterone(IM); Striant (Buccal); Testim (Gel); Testopel (Implant) Testosterone Hypogonadism, Delayed Male Puberty Transdermal Patch (ER): 2mg/24hr, 4mg/24hr, Topical gel/jelly: 1 or 1.62%; Buccal patch (ER): 30mg; SubQ Implant: 75mg; IM Susp: 100mg/ml 200mg/ml Topically, Buccal, IM Varies N/A Adolescent males 13+ (IM and Pellet) Endogenous androgen responsible for normal growth & development of male sex organs
Adrenal Glucocorticoid; Anti-inflammatory; Corticosteroid; Dental Agent; Endocrine-Metabolic Agent Aristocort; Kenalog; Nasacort Triamcinolone Acetonide Acquired Hemolytic Anemia; allergic rhinitis; asthma; collagen disease; disorder of endocrine system, eye, GI tract, respiratory system, skin; ganglion & synovial cyst; inflammatory disorder of musculoskeletal system; leukemia; malignant lymphoma; MS; Inj. Susp: 10mg/ml, 40mg/ml; mucous membrane paste 0.1%; nasal spray: 55mcg/spray; topical cream & ointment; 0.025, 0.1, 0.5%; topical lotion: 0.025, 0.1%; topical spray: 0.147mg/gm Intra-articular, intralesional, IM, intravitreal, nasal, topical Varies Varies 2YO+ nasal (dental paste – not for children) Synthetic corticosteroid with anti-inflammatory, antipruritic and antiallergic properties
Monophasic Contraceptive Combo (Estrogen and Progestin) Aviane; Alesse; Loestrin 24 Fe; Ortho Novum; Ovcon; Ovral; Ortho-Cept; Sprintec; Yasmin; Yaz; Monophasic Contraceptive Combo Contraception Varies Oral 1 tab QD, same time each day Safety & efficacy before menarche have not been established Suppresses gonadotropins; prevents ovulation and induces changes in the endometrium and cervical mucus to decrease the possibility of fertilization and implantation
Monophasic Contraceptive Combo Ortho Evra Ethinyl Estradiol/ Norelgestromin Contraception Transdermal Patch (ER): 35mcg/24hr 150mcg/24hr Transdermal 1 patch every week for 3 weeks, patch-free for week 4 Safety & efficacy before menarche have not been established Suppresses gonadotropins; inhibits ovulation; changes cervical mucus and the endometrium
Created by: scottamus123