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Dermatologic Drugs
Antipsoriatic drugs
| Term | Definition |
|---|---|
| Tazarotene | (most common) receptor-selectted retinoid -normalize epidermal differentiation, reduce the influx of inflammatory cells into the skin *Tx of plaque psoriasis & mild-severe facial acne *preg X cat. :( |
| Tar-Containing products | 1st meds used to treat psoriasis -antiseptic, antibacterial, antiseborrheic property & works to soften and loosen scally of crusted areas of the skin. A/E: skin burning, photosensitivity, irritations |
| anthralin | -Inhibits DNA synthese & mitosis w/i the epidermis to reduce psoriatic lesions -preg C category |
| Calcipotriene | synthetic Vit D3 analogue, works by binding to Vit B3 receptors in skin cells - helps to regulate the growth & reproduction of keratinocytes A/E: skin irritation, worsening psoriasis, skin atrophy, folliculitis |
| Etanercept | Decrease progression S&S's of rheumatoid arthritis -binds to tumor necrosis, making it inactive -60% absorbed after subcute injection |
| Alefacept | given IM -used to Tx mod-severe chronic plaque psoriasis -Immunosuppressant(works by stopping the action of certain cells in the body) A/E: dizziness, pain, redness, swelling, and bleeding where meds were injected |
| Ustekinumab (Stelara) | *newest (given subcute) injectable for plaque psoriasis pt must receive FDA approval A/E: increased risk for infection |
Created by:
Ashleigh0101
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