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Pharm Neuro part 1

Seizure disorders, Anesthesia, ADHD and Narcolepsy

Generic name (Brand name)Indication
Phenytoin (Dilantin) Hydantoin for epilepsy SE: Drowsiness, skin rash, gingival hyperplesia D: Give with meals,inject IV slowly CONTRA:Bradycardia, skin rash, seizures from low blood sugar PT: Do not drive, brush teeth with a soft brush, report rash, don't st
Carbamazepine (Tegretol) Iminostilbene for seizure disorder, bd SE: Fluid retention, headache, blurred vision, skin rash D: Give at bedtime as much as you can, check Asians with gene HLA-B*1502 for severe skin rash PT: No driving, use sunscreen CONTRA:hematologic disorders, HF
Valproic acid (Depakot, Depakene, Depacon) For all seizure types SE: Upset GI, bruising, bleeding, skin rash, liver toxicity D:Give with food, oral or IV CONTRA: Liver disorder, thrombocytopenia, kidney disease
Anesthesia drug types Local - Lidocaine General - Barbiturates, Benzodiazepine, Opioids
Lidocaine (Xylocaine) Local anesthesia SE: restlesness, irritability, tremors, hypOtension, administer Ephedrine if hypotension worsens PT: Report dizziness, difficulty breathing CONTRA: Bradycardia, Heart block, older adults. Beta blockers increase effect
Sodium Thiopental (Pentothal) General anesthesia/Barbiturate SE: decrease heart rate, BP
Midazolam (Versed), Diazepam (Valium) General anesthesia/Benzodiazepine SE: Amnesia, cardiac/resp arrest D:Administer IM into a large muscle mass PT: Be aware of memory loss, CONTRA: Glaucoma, Parkinson's, cardiac/pulmonary/renal disorder
Fentanyl (Sublimaze) General anesthesia/Opioid SE: Sedation, nausea, resp. depression, D: Available in stick lozenges and IV PT:Expect drosiness, report nausea CONTRA: Substance abuse, MG, liver/kidney disorders
ADHD and Narcolepsy drugs Amphetamines, methylphenidates, non-amphetamines
Amphetamine and dextroamphetamine sulfate (Adderall) SE: Insomnia, nervousness, hypertension, weight loss D: No caffeine, take early no later than 4pm CONTRA: Hypertensions, hyperthyroidism, cardiovascular disease
Methylphenidate (Ritalin, Concerta) SE: Insomnia, nervousness, hypertension, weight loss D:is available in patch forms, apply in hip area, press for 30 sec PT: Take as early as possible, report anorexia CONTRA: Heart defects, depression, hypertension, hyperthyroidism
Modafinil (Provigil) - non-amphetamine SE: Nausea, diarrhea, minor CNS effects, rash D:Give in the morning for narcolepsy CONTRA: hypertension, heptaic/renal impairment
Created by: lvn9561