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Pharm

Pharm Final Review - SPC

QuestionAnswer
What are the Diuretic Drugs? Lasix, Mannitol, and Diamox
Lasix Diurectic, Fast onset, Loss Potassium, Loss hydrogen ions = promotes Metabolic ALKALOSIS
Mannitol Osmotic diuretic, slow, spares electrolytes, tx of head trauma
Diamox Diuretic promote Metbolic ACIDOSIS
Sedative/Hypnotic/Narcotic drugs Haldol, Dilantin, Campazine, Versed, Diprivan, Ativan, Morphine Sulfate, Demerol, Narcan
Haldol good for DTs, and highly agitated states
Dilantin anti-epileptic, good to prevent seizures
Compazine antiemetic = tx of nausea
Versed short acting sedative/hypnotic, excellent for short term memory block
Dipravan sedative/hypnotic, dose dependent, Used as drip for continuous sedation, Fast onset, quick recovery
Ativan anti-anxiety, PREOP
Valium anticonvusant to tx occuring seizure
Morphine Sulfate Narcotic analgesic. Relax Smooth Muscles surrounding Bl. Vessels which drops preload and may drop BP. Can result in bronchospasm by releasing histamine. Constipation. Reduce drive to breath by lowering sensitivity to CO2
Demerol narcotic analgesic, 50 mg standard dose
Narcan antidote for narcotic and barbiturate overdose
Non-narcotic Analgesic Drugs ASA(Asprin), COX 2
ASA(Asprin) avoid w/viral symptoms(fever, side aches, may worsen Asthma by dropping PGE levels)
COX 2 inhibitors For Pain - analgesic
Anticholinergic Drugs Atrovent(Ipratropium Bromide), and Spiriva(Tiotropium Bromide)
Atrovent(Ipratropium Bromide) as a solution the dose is 0.5mg and available as MDI. Not w/soy or peanut allergy
Spiriva(Tiotropium Bromide) DPI, long lasting, 24-36 hrs. QDay
What do Anticholinergics do? Promotes bronchodilation in the LARGER airways by preventing parasympathetic response(bronchoconstriction)because it is an antagonist action on the M3 receptor. Avoid Mask w/all anticholinergics due to eye problems due to dilation of pupils
Combo Meds Advair DPI, DuoNeb, Combivent
Advair DPI slow onset, maintenence med, slow onset sympathomimetic with steroid
DuoNeb solution is anticholinergic Atrovent(Ipratropium Bromide)w/ sympathomimetic Albuterol Sulfate
Combivent MDI version of DuoNeb, NOT with soy/peanut allergies
Glucocorticoids stops all inflammation, takes hours for onset. Enhances and promote Beta response. Problems - Promotes Metabolic ALKALOSIS, mood swings, fat deposits, hair growth, atrophy of adrenal gland
Leukotrienes (LT) inhibitors reduce/prevent inflammation response due to asthma. Singulair(Montelukast)LT receptor antagonist
How do Anticholinesterase Meds work act by promoting AE by inhibiting acetylcholinesterase, the enzyme which breaks down AE. Tensilon to dx Myasthesia Gravis
Sympathetic Nervous System A1 = Vasoconstriction, B1= positive INO and CHRONO, B2= relax smooth musc. to dilate airways. c3'5'AMP = smooth muscle relax which causes airway dilation and phosphodiesterase reduces c3'5' to c5'AMP which stops muscle relax
Sympathomimetic Meds Racemic Epi, Albuterol Sulfate, Xopenex, Brovana, Foradil(formoterol)
Action of Sympathomimetics? Meds work in SMALLER airways by stim of B2 which relaxes Smooth muscles around airways. Solutions should be clear, if not = oxidation and not administered b/c bronchospasm
Racemic Epinephrine fast catacholamine, A1, B1, B2 agonist. Dose = 0.5ml for airway edema
Albuterol Sulfate (Ventolin, Proventil) 5mg/ml - onset up to 15 minutes
Xopenex racemic albuterol, pure R isomer, 2 strengths, lower B1 activity = Lower tachycardia and less B2 effects which = lower occurence tremor
Brovana long lasting 12 hr sympathomimetic
Foradil(formoterol) DPI, long lasting 12 hours
Mucolytics Mucomyst(n-acetylcysteine) and Pumozyme(Dornase alpha)
Mucomyst(n-acetylcyteine) disrupts mucus viscosity and elasticity, airway irritant. Re-Eval 3-5 days, 96hrs after opening toss
Pulmozyme(Dornase Alpha) Lysis DNA of infectious mucus(pneumonia), purulent secretions. Refrigerate. Toss if cloudy. HCW do not breathe
Methylxanthines Relax smooth muscles to prevent bronchoconstriction, improves contraction and endurance of diaphragm. Anti-inflammatory effects beneficial in tx asthma. Cause arrhythmias, nausea, seizure. Aminophylline is methylxanthine
Lidocaine Given w/bronchoscopy cna cause methemoglobinemia, used to tx PVC. IV drip
Dobutrex + INO, improves stroke V by B1 stim
Digitalis + INO, improves stroke V by promoting fee Ca+ for contraction
Nitrates Vasodilators reduce Pre-load and Afterload while improving coronary perfusion by dilation of coronary arteries
Dopamine High dose = vasopressor for tx low BP(shock)Low dose = diuretic
How do Anticholinesterase Meds work act by promoting AE by inhibiting acetylcholinesterase, the enzyme which breaks down AE. Tensilon to dx Myasthesia Gravis
Sympathetic Nervous System A1 = Vasoconstriction, B1= positive INO and CHRONO, B2= relax smooth musc. to dilate airways. c3'5'AMP = smooth muscle relax which causes airway dilation and phosphodiesterase reduces c3'5' to c5'AMP which stops muscle relax
Sympathomimetic Meds Racemic Epi, Albuterol Sulfate, Xopenex, Brovana, Foradil(formoterol)
Action of Sympathomimetics? Meds work in SMALLER airways by stim of B2 which relaxes Smooth muscles around airways. Solutions should be clear, if not = oxidation and not administered b/c bronchospasm
Racemic Epinephrine fast catacholamine, A1, B1, B2 agonist. Dose = 0.5ml for airway edema
Albuterol Sulfate (Ventolin, Proventil) 5mg/ml - onset up to 15 minutes
Xopenex racemic albuterol, pure R isomer, 2 strengths, lower B1 activity = Lower tachycardia and less B2 effects which = lower occurence tremor
Brovana long lasting 12 hr sympathomimetic
Foradil(formoterol) DPI, long lasting 12 hours
Mucolytics Mucomyst(n-acetylcysteine) and Pumozyme(Dornase alpha)
Mucomyst(n-acetylcyteine) disrupts mucus viscosity and elasticity, airway irritant. Re-Eval 3-5 days, 96hrs after opening toss
Pulmozyme(Dornase Alpha) Lysis DNA of infectious mucus(pneumonia), purulent secretions. Refrigerate. Toss if cloudy. HCW do not breathe
Methylxanthines Relax smooth muscles to prevent bronchoconstriction, improves contraction and endurance of diaphragm. Anti-inflammatory effects beneficial in tx asthma. Cause arrhythmias, nausea, seizure. Aminophylline is methylxanthine
Lidocaine Given w/bronchoscopy cna cause methemoglobinemia, used to tx PVC. IV drip
Dobutrex + INO, improves stroke V by B1 stim
Digitalis + INO, improves stroke V by promoting fee Ca+ for contraction
Nitrates Vasodilators reduce Pre-load and Afterload while improving coronary perfusion by dilation of coronary arteries
Dopamine High dose = vasopressor for tx low BP(shock)Low dose = diuretic
How do Anticholinesterase Meds work act by promoting AE by inhibiting acetylcholinesterase, the enzyme which breaks down AE. Tensilon to dx Myasthesia Gravis
Sympathetic Nervous System A1 = Vasoconstriction, B1= positive INO and CHRONO, B2= relax smooth musc. to dilate airways. c3'5'AMP = smooth muscle relax which causes airway dilation and phosphodiesterase reduces c3'5' to c5'AMP which stops muscle relax
Sympathomimetic Meds Racemic Epi, Albuterol Sulfate, Xopenex, Brovana, Foradil(formoterol)
Action of Sympathomimetics? Meds work in SMALLER airways by stim of B2 which relaxes Smooth muscles around airways. Solutions should be clear, if not = oxidation and not administered b/c bronchospasm
Racemic Epinephrine fast catacholamine, A1, B1, B2 agonist. Dose = 0.5ml for airway edema
Albuterol Sulfate (Ventolin, Proventil) 5mg/ml - onset up to 15 minutes
Xopenex racemic albuterol, pure R isomer, 2 strengths, lower B1 activity = Lower tachycardia and less B2 effects which = lower occurence tremor
Brovana long lasting 12 hr sympathomimetic
Foradil(formoterol) DPI, long lasting 12 hours
Mucolytics Mucomyst(n-acetylcysteine) and Pumozyme(Dornase alpha)
Mucomyst(n-acetylcyteine) disrupts mucus viscosity and elasticity, airway irritant. Re-Eval 3-5 days, 96hrs after opening toss
Pulmozyme(Dornase Alpha) Lysis DNA of infectious mucus(pneumonia), purulent secretions. Refrigerate. Toss if cloudy. HCW do not breathe
Methylxanthines Relax smooth muscles to prevent bronchoconstriction, improves contraction and endurance of diaphragm. Anti-inflammatory effects beneficial in tx asthma. Cause arrhythmias, nausea, seizure. Aminophylline is methylxanthine
Lidocaine Given w/bronchoscopy cna cause methemoglobinemia, used to tx PVC. IV drip
Dobutrex + INO, improves stroke V by B1 stim
Digitalis + INO, improves stroke V by promoting fee Ca+ for contraction
Nitrates Vasodilators reduce Pre-load and Afterload while improving coronary perfusion by dilation of coronary arteries
Dopamine High dose = vasopressor for tx low BP(shock)Low dose = diuretic
How do Anticholinesterase Meds work act by promoting AE by inhibiting acetylcholinesterase, the enzyme which breaks down AE. Tensilon to dx Myasthesia Gravis
Sympathetic Nervous System A1 = Vasoconstriction, B1= positive INO and CHRONO, B2= relax smooth musc. to dilate airways. c3'5'AMP = smooth muscle relax which causes airway dilation and phosphodiesterase reduces c3'5' to c5'AMP which stops muscle relax
Sympathomimetic Meds Racemic Epi, Albuterol Sulfate, Xopenex, Brovana, Foradil(formoterol)
Action of Sympathomimetics? Meds work in SMALLER airways by stim of B2 which relaxes Smooth muscles around airways. Solutions should be clear, if not = oxidation and not administered b/c bronchospasm
Racemic Epinephrine fast catacholamine, A1, B1, B2 agonist. Dose = 0.5ml for airway edema
Albuterol Sulfate (Ventolin, Proventil) 5mg/ml - onset up to 15 minutes
Xopenex racemic albuterol, pure R isomer, 2 strengths, lower B1 activity = Lower tachycardia and less B2 effects which = lower occurence tremor
Brovana long lasting 12 hr sympathomimetic
Foradil(formoterol) DPI, long lasting 12 hours
Mucolytics Mucomyst(n-acetylcysteine) and Pumozyme(Dornase alpha)
Mucomyst(n-acetylcyteine) disrupts mucus viscosity and elasticity, airway irritant. Re-Eval 3-5 days, 96hrs after opening toss
Pulmozyme(Dornase Alpha) Lysis DNA of infectious mucus(pneumonia), purulent secretions. Refrigerate. Toss if cloudy. HCW do not breathe
Methylxanthines Relax smooth muscles to prevent bronchoconstriction, improves contraction and endurance of diaphragm. Anti-inflammatory effects beneficial in tx asthma. Cause arrhythmias, nausea, seizure. Aminophylline is methylxanthine
Lidocaine Given w/bronchoscopy cna cause methemoglobinemia, used to tx PVC. IV drip
Dobutrex + INO, improves stroke V by B1 stim
Digitalis + INO, improves stroke V by promoting fee Ca+ for contraction
Nitrates Vasodilators reduce Pre-load and Afterload while improving coronary perfusion by dilation of coronary arteries
Dopamine High dose = vasopressor for tx low BP(shock)Low dose = diuretic
Oxygen Acts to dilate pulmonary vascular bed lowering PVR and reduce work of R heart
Created by: mac6672