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Top 200 #8

ClassBrandGenericIndicationDose FormRouteAdult DosePed. DoseMOA
Antianxiety; Benzodiazepine (Short or Intermediate Acting) Xanax Alprazolam Anxiety; panic disorder Oral Tablet: 0.25, 0.5, 1, 2mg; ODT: 0.25, 0.5, 1, 2; ER Tablet: 0.5, 1, 2, 3mg; Oral Soln: 1mg/ml Oral Anxiety:0.25-0.5 tid Panic disorder: 0.5 tid max: 10mg/day N/A Possibly binds to various stereo-specific receptors in the CNS
Benzodiazepine (Short-Intermediate Acting); Hypnotic Restoril Temazepam Insomnia Oral Capsule: 7.5, 15, 22.5, 30mg Oral 7.5-30mg at bedtime N/A Hypnotic agent belonging to the benzodiazepine class
Antidiabetic; Ultra Rapid Acting Insulin NovoLog; NovoLog Flexpen Insulin Aspart (70/30) Type 1&2 DM SubQ Susp/Soln: 100U/ml (10ml vials) (3ml flexpen) SubQ Inject dose 5-10 minutes before a meal; dose varies 2YO+ Inject dose 5-10 minutes before a meal; dose varies Binds to insulin receptors on muscle and fat cells allowing for increased cellular uptake of glucose and subsequent decreases in blood glucose
Antidiabetic; Ultra Rapid Acting Insulin Humalog; Humalog Kwikpen Insulin Lispro Type 1&2 DM SubQ Susp/Soln: 100U/ml (10ml vials) (3ml kwik-pen) SubQ Inject dose 5-10 minutes before a meal; dose varies 3YO+ Inject dose 5-10 minutes before a meal; dose varies Binds to insulin receptors on muscle and fat cells allowing for increased cellular uptake of glucose and subsequent decreases in blood glucose
Antidiabetic; (R) Rapid Acting and (N) Intermediate Acting Humulin N; Humulin R Insulin Type 1&2 DM (N)Susp:100U/ml (R) soln: 100U/mL, 500U/mL SubQ dosages need to be individualized Type 1: 0.5-0.6 U/kg/day up to 3x /day Type2: 0.2-0.6 U/kg/day 12 yo and older :same as adults Binds to insulin receptors on muscle and fat cells allowing for increased cellular uptake of glucose and subsequent decreases in blood glucose
Antidiabetic; Long Acting Insulin Lantus; Lantus Solostar Insulin Glargine Type 1&2 DM SubQ Soln: 100U/ml Pen-Injector SubQ Individualized dosing for once daily (same time each day) 6YO+ individualized dosing Binds to insulin receptors on muscle and fat cells allowing for increased cellular uptake of glucose and subsequent decreases in blood glucose
Antidiabetic; Long Acting Insulin levemir Insulin Detemir Type 1&2 DM SubQ Soln: 100U/ml Pen-Injector SubQ Individualized dosing QD-BID 2YO+ individualized dosing Binds to insulin receptors on muscle and fat cells allowing for increased cellular uptake of glucose and subsequent decreases in blood glucose
Antidiabetic; Dipeptidyl Peptidase IV Inhibitor Januvia; Janumet Sitagliptin Sitagliptin/ Metformin Type 2 DM Oral Tablet: Januvia:25, 50, 100mg Janumet:50/500,50mg/1000mg Janumet XR: 50/500,50/1000,100mg/1000mg Oral 100mg QD with or without food N/A DPP-4 inhibitor =increase insulin and decrease glucagon
Antidiabetic; GLP-1 Receptor Agonist Victoza Liraglutide Type 2 DM SubQ Soln: 6mg/ml Pen-Injector SubQ 0.6-1.2mg QD, may increase to 1.8mg QD N/A GLP-1 receptor agonist that acts to increase insulin release in the presence of elevated glucose concentrations, decrease glucagon secretion in a glucose-dependent manner, and delay gastric emptying
Antidiabetic; GLP-1 Receptor Agonist Byetta, Bydureon Exenatide Type 2 DM SubQ Soln: (pen-injector) 5mcg/0.2ml 10mcg/0.4ml SubQ IR: initial = 5mcg BID within 60mins before AM & PM meal (approx. 6 hrs apart); Maintenance: may increase to 10mcg BID N/A Acts as an incretin mimetic agent to enhance glucose-dependent insulin secretion
Antidiabetic; Thiazo-lidinedione Actos Pioglitazone Type 2 DM Oral Tablet: 15, 30, 45mg Oral Initial = 15-30mg QD; max of 45mg QD N/A Thiazolidinedione antidiabetic agent & PPARĪ³ agonist, is dependent on the presence of insulin for its MOA
Biguanide; Hypoglycemic Glucophage; Riomet; Fortamet; Metformin; Type 2 DM Oral Tablet: 500, 850, 1000mg; ER Tablet: 500, 750, 1000mg; Oral Soln(Riomet): 500mg/5ml Oral Type 2: IR: 500 BID-850 QD.Max: 2550mg/day ER: 1000 QD.max: 2000mg/day >10 yo: IR: same as adults ER: n/a Lowers both basal and postprandial glucose levels in type 2 DM pts through several mechanisms: decreases hepatic glucose production, decrease intestinal absorption, and increases peripheral glucose uptake & utilization by improving insulin sensitivity
Biguanide; Hypoglycemic; 2nd gen. sulfonylurea Glucovance Metformin/Glyburide Type 2 DM Oral Tablet: Gly/Met 1.25mg/250mg 2.5mg/500mg 5.0mg/500mg Oral 1.25/250 bid Max: 10mg/2000mg N/A Metformin MOA + Glyburide stimulates pancreatic beta cells to produce insulin.
Amphetamine, CNS Agent/ Stimulant Adderall; Adderall XR Amphetamine Salts ADHD; narcolepsy ER Capsule: 5, 10, 15, 20, 25, 30mg; IR Tablet: 5, 7.5, 10, 12.5, 15, 20, 30mg Oral ADHD: 20mg ER cap QD; 5mg IR tab QD-BID Narcolepsy: 5-60mg IR tab QD or divided doses 3YO+ dose varies based on age Noncatechol sympathetic amine with CNS stimulant activity; purported to block the reuptake of NE and dopamine into the presynaptic neuron & increase their release into the extraneuronal space
Amphetamine Related; CNS Agent/ Stimulant Concerta; Daytrana; Ritalin; Metadate; Methylin Methylphenidate ADHD; narcolepsy Metadate:ER-C: 10,20,30,40,50,60mg; ER-T:20mg. Ritalin:T: 5,10,20mg; ER-T:10,20,30,40 Concerta:ER Tab: 10,18,20,27,36,54mg Methylin:Chew T: 2.5,5,10mg;Soln:5mg, 10mg/5mL Patch(Daytrana): 10, 15 20,30mg/9hr Oral, Topical Varies usually QAM Max: 60mg/day 6YO+ Dose varies (Patch may be used on ped.) Blocks the reuptake of NE and dopamine into the presynaptic neuron, thus increasing the concentrations of these monoamines in the extraneuronal space
Amphetamine Related; CNS Stimulant Focalin XR Dexmethylphenidate ADHD ER Capsule(XR): 5, 10, 15, 20, 25, 30, 35, 40mg; IR Tablet(Focalin): 2.5, 5, 10 Oral Initial = 10mg QAM, adjust dose weekly in 10mg increments (max of 40mg/day) 6YO+ ER, initial: 5mg QAM, adjust weekly in 5mg inc. Max ER: 30mg/day Max IR: 20mg/day Thought to block the reuptake of NE and DA into the presynaptic neuron, increasing the concentrations of these monoamines in the extraneuronal space
Amphetamine; CNS Stimulant Vyvanse Lisdexamfetamine Dimesylate ADHD, Binge eating disorder Oral Capsule: 10, 20, 30, 40, 50, 60, 70mg Oral Initial: 30mg QAM, may increase by increments of 10 or 20mg per day at approx. 1 week intervals Max: 70mg/day 6YO+ same dosing as adults May block the reuptake of NE and DA
Antianxiety; Anticonvulsant; Benzodiazepine (Short or Intermediate Acting) Klonopin Clonazepam Panic disorder; Seizure Oral Tablet: 0.5, 1, 2mg; ODT: 0.125, 0.25, 0.5, 1, 2mg Oral 0.5 bid-tid.Max: 4mg/day seizure: >10yo: 0.5 tid <10yo: 0.01-0.03 bid-tid Believed to enhance GABA activity
Antianxiety; Anticonvulsant; Benzodiazepine (Long Acting) Valium Diazepam Alcohol withdrawal syndrome; anxiety; sedation; seizure; skeletal muscle spasm; status epilepticus Inj. Soln: 5mg/ml; Oral concentrate: 5mg/ml; Oral Tablet: 2, 5, 10mg; Rectal Gel: Diastat AcuDial: :10, 20mg. Diastat Pediatric: 2.5mg IM device: 10mg/2mL Oral, injection, IM, Rectal 2-10mg bid-qid > 6mo: 1-2.5 mg tid-qid Reduces neuronal depolarization resulting in decreased action potentials. Enhances action of GABA by tightly binding to GABA-A receptors
Antianxiety; Benzodiazepine (Short or Intermediate Acting) Ativan Lorazepam Anxiety; insomnia; premedication for anesthetic procedure; status epilepticus Inj. Soln: 2mg/ml, 4mg/ml; Oral concentrate: 2mg/ml; Oral Tablet: 0.5, 1, 2mg Oral, Injection anxiety: 1-2 mg bid-tid insomnia: 2-4 mg QHS 12YO+ dose varies Binds highly to the GABA-BZ receptor complex without displacing GABA
Created by: scottamus123