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Stack #186685
INF diseases
| Question | Answer | ||||
|---|---|---|---|---|---|
| Acute/Chronic Bronchitis | M.pneum, S.pneu, H.influ,M.catarrhCh.pneo | Acute | Ery, Clari, Azithromycin | ||
| Chronic | Amox, Amox-clavu, Septra, Ery, Azi, Clari, Doxy, cafaclor, cefprozil, cefuroxime | ||||
| (same as newborn to 1 month) | >60 years | S.pneumoniae, List.monocytogenes, Gm-ve enterics | Ampicillin & aminoglyco/Vancoor ceftriaxone or cefotaxime | ||
| Endocarditis | Strep ans Satph species | inc ESR or CRPsplinter hemorrhage and petechiae, visualization of vegetation | penicillin suscept strepto | Pen G alone or PenG with Genta orCeftriaxone alone or Vanco | |
| Penic resist strepto | Same as above | ||||
| Staph without prosthehtic material9methicillin sensitive) | Naficillin or Oxacillin(with Genta)Cefazolin (with or without Genta)Vanco (if allergic to penicillin) | ||||
| Stap without prosthetic material ( methicillin resistant) | Vancomycin | ||||
| PENUMONIA | Neonatal | E.coli, Gr B Step, List.monoctogenesis | Ampi and GentaCefotaxime & genta | ||
| 1-3 months | Ch. tracho, Bordetella | ery, clari, cefuroxime | |||
| 3 months to 5 years | C.trachomatis, S.pneom | clari, cefuroxime, cefotaxime | |||
| 5-18 years | My.pneum, S.pneum, Ch,pneum | clari, cefuroxime, erythro | |||
| Adult-Comm Acq | S.pneum, M.pneum, Kleb.pneum, H.infl | Ampulatory:macrolidesfluroquionolonesHosp: ceftriaxone or cefotaxime with or without macrolidesor Fluroquinolones | |||
| Adult-Hosp Acq | K.pneum, Staph.aureus, E. aerogenesSerratia sppAcinobacter sppP.aureginosa | Aminoglycosides with one of the following: Cetatoxime, ceftrioxone,cefepime, peropenem, imipenem,ticarcillin/-calvul,piperacillin-tazobactam. Vanco to be added if MRSA | |||
| Adult-Aspiration | Mouth Anaerobes | Uncomplicated: Pen G, ClindaHosp acq: Ticarcillin-clav acid, piperacillin-tazobactum | |||
| Tuberculosis | M.tuberculosis | wt loss, fever, night sweats persistant prod cough. Latent dis-+ve PPD testHIV pts may not react to PPD test. Sputum or ling biopsy may be acid fast stained | Latent(INH sensitive) | Isoniazid | 9 months |
| Latent (INH resistant) | Rifampin + Pyrazinamide | 2 months | |||
| Active disease | INH+Rifa+Pyrazinamide | 2- months | |||
| Infectious Diarrhea | Staph aureus | Supportive | |||
| bacillus creus | Supportive | ||||
| Clostridium perfringes | Supportive | ||||
| E.cloi | Oot Patient:SupportiveHosp: Septra or Fluoroq | ||||
| Salm spp | Septra or fluoroq | ||||
| Shigella spp | Septa | ||||
| Campylobacter | Macrolides or Fluoro | ||||
| Yersinia enterocolitica | Fluoro | ||||
| Vibrio parahaemolyticus | tetra, or fluoro | ||||
| Vibrio cholerae | tetra or fluoroquinolone | ||||
| E.coli | supportive | ||||
| Skin and Soft tissue | cellulitis, secondary wound infection | Strep pyrogenesStaph aureus | edema of skin and erythema | cellulitis: Gr. A Strep, Stapa aureus | O.P: dicloxacillin, cefadroxil,cephalexin,erythromycinI.P: cefazolin,erySevere:Vanco |
| Diabetic foot infections | proteus spp, e.coli, anerobic streptococci, S.aureus, Bacteroides fragilis | Clinda or cephalexinSevere: ticarcillin-clav acidor other b-lactamase inhibitor, Vanco if MRSA | |||
| Decubitus ulcers | Gm-ve bacilli, anerobes, P.auregenosa | same as above | |||
| Urinary Tract Infections | Gm-ve facultatively anerobic rods.Hosp catherized pts..Pseudomonas and Staph spp | urethritis,cystitis,prostatitis,pyelonephritisdysuria,urgeny,frequency,nocturia,suprapubic pain/pressure. Upper UTI..flank pain and fever | Acute Uncomplicated cystitis | E.coli, Staph saprophyticus | SeptraQuinolinw |
| Acute pyelonephritis | E.coli, Proteus mirabilis, Kleb.pneum,Enterococcus | quinolone, SeptraSevere: parenteral quinolone, extened spectrum penicillin plus aminoglycoside | |||
| Prostatitis | E.coli, proteus spp, Kleb,pneum | quinoloneSeptra | |||
| Gonorrhea | N.gonorrhea | Gm stain and culture if infected secretions, Enzyme immunoassay and DNA probes | Urethritis.15%..pelvic inflammatory dis...inferility | 3rd genration cephalosporins and also Vs chlamydial infection | |
| Uncomplicated Adult | Ceftriaxone or Spectinomycin | ||||
| Infant born of untreated mother | cefotaxime | ||||
| Latent disease | Ceftriaxone 1gm qd X 10 ds | ||||
| Syphillis | T.pallidum | Primary:painless lesion 21 days after exposure for 8 weeks then diappearsSecondary: 2-6 weeks agter onset of primary stage:rashes and flu like symptoms, disappear 4-10 weeks if untreated.Tertiary:in2-25 years:paresis,deafness,dementia,aortic insuff. | dark field fluoroscent with serology VDRL and Rapid Plasma Reagin (RPR) tests | Uncomplicated adult | benzathine penicillin G |
| Infant of untreated mother | PenG | ||||
| Secondary/latent | benz penG X3 weeks | ||||
| tertiary | PenG2- million q4h f 10-14 ds | ||||
| SEPSIS | SIRS in response to an infection | >38deg or <36 degHR>90bpmRR>20 breaths/minPaCo2<32torrWBC>12,000 cells/mm3or <4000 celles/mm3or >10% immature band forms | Gm +ve and -ve | cefotaximeceftriaxonecefepimeticarcillin/calv acidpiperacillin-tazobactammeropenumimipenem aith an aminoglyciseide(tobramycin,genta.amikacinVANCO if Gm +ve | |
| Tick-Borne Systemic febrile syndromes | Lyme Dis | Borr.burgdorferi | Doxy | Cefuroxime | |
| Rocky Mntn Spooted Fever | Rick. reickettsii | Doxy | chloramphenicol | ||
| Ehrlichiosis | Ehrlichia phagocytpphila | Doxy | Tetracyclne | ||
| Tularemia | Francisella tularensis | Genta or tobra | chlorampheicolorCipro | ||
| Systemic Fungal Infections | |||||
| Invasive pulm dis | Aspergillosis spp | AmphotericnB itraconazole,caspofungin,voriconazole | |||
| Cutaneous,pulm or extrapulm | blstomyces dermatitidis | Itra,amphB,fluc | |||
| Blood stream inf | Candida albicans | fluco,amphB | |||
| Primary pulm dis | coccidioides immitis | itra,fluc | |||
| Menigitis | Cryptococcus neoformans | AmphB+flucytosine,fluconazole | |||
| Pulm disseminated or localized | histoplasma capsulatum | itra(moderate)AmphB(severe) | |||
| Influenza | A,B and C | A | Prophylaxis | oseltamivir, rimantadine,amantadine | |
| A | treatment | Zanamivir,oselta.amantadine,rimantadine | |||
| B | Proph | oseltamivir | |||
| B | treatment | Zanamivir,oseltamivir | |||
| Herpes simplex | Initial episode | Acyclo | |||
| reoccurrence | Famciclovir | ||||
| Chronic Suppresion | Valacyclovir | ||||
| Immunocompromised resist to acyclovir | Foscarnet | ||||
| Cytomegalovirus | Retinitis, colitis, esophagitis | Ganciclovir,valganciclovirfoscarnetcidofovirfomivirsen | |||
| varicella zoster | chickenpox,shingles | Acyclovir | |||
| Varicella zoster | immunocompromised, resitst to acyclovir | Foscarnet | |||
| Meningitis | many GM + and -ve | inc WBC, inc CSF protein, Dec CSF Gluc, Bacterial large inc, smaller inc for fung&viral | Age related Tx | ||
| Newborn to 1 month | Gm -ve entericsGp B StrepList. monocytogenes | Ampicillin & Aminoglycosides/cefotaxime/ceftriaxon | |||
| 1 month to 29 years | H. influenzaeN. MeningitidsisS.Pneumoniae | cefatoxime / ceftriaxone and Vanco | |||
| 30-60years | S.pneumoniae, N.meningitidis | same as above |