Save
Busy. Please wait.
or

show password
Forgot Password?

Don't have an account?  Sign up 
or

Username is available taken
show password

why


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.


Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't know
Remaining cards (0)
Know
0:00
share
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

CNS Drugs

QuestionAnswer
Class of drugs for anxietic disorders (2) & examples Benzodiazepines eg. Midazolam, lorazepam and diazepam. Non- benzodiazepines eg. Zolpidem
Benzodiazepine: Mode of action Binds to specific sites in the CNS and potentiates GABA (an inhibitory neurotransmitter) actions by increasing the frequency of Cl channel opening. This moderates neural transmission and reduces anxiety. It is GABA dependent.
Benzodiazepine: Characteristics It has short acting (eg. midazolam, which is cleared from the body within 2-4h), intermediate (eg. lorazepam which is cleared in 8h) and long acting (diazepam, cleared in 16h) drugs.
Benzodiazepine: Characteristics It has short acting (eg. midazolam, which is cleared from the body within 2-4h), intermediate (eg. lorazepam which is cleared in 8h) and long acting (diazepam, cleared in 16h) drugs.
Benzodiazepine: Uses Anxiety disorders, sedation before gastroscopy.
Benzodiazepine: Uses Anxiety disorders, sedation before gastroscopy.
Benzodiazepine: Toxicity Drowsiness, increased reaction time, decreased motor skills, anterograde amnesia. Affects breathing and BP. Paradoxical effects are rare and can include irritability, garrulousness, hallucination. Tolerance, dependence, withdrawal, neonatal toxicity.
Non-benzodiazepine hypnotics: MOA Same as benzodiazepine
Non-benzodiazepine hypnotics: Toxicity Withdrawal anxiety, abuse potential, tolerance, dependence.
Class of drugs for insomnia: Anti histamines (mostly 1st generation)
Anti-histamines: MOA Binds to H1 receptor, eliminating histamine actions by competitive inhibition.
Class of drugs for insomnia: Anti histamines (mostly 1st generation)
Anti-histamines: Uses Used to relieve nasal congestion, allergic response and hypnotic agents.
Anti-histamines: MOA Binds to H1 receptor, eliminating histamine actions by competitive inhibition.
Anti-histamines: Toxicity Dry mouth, increased appetite (can lead to obesity), blurring of vision and constipation.
Classes of drugs for depression: (2) Selective serotonin re-uptake inhibitors, eg. Fluoxetine, paroxetine. Tricyclic anti-depressants eg. Imipramine, amitriptyline.
SSRIs: MOA Inhibits serotonin re-uptake transporter, enabling neurotransmitter present at synapse to continue acting on post-synaptic neurons. This corrects the monoamine deficiency.
SSRIs: Toxicity Anxiety, weight gain/loss (depending if the person eats alot or too little when he is depressed), headache, nausea, sexual dysfunction (decreased libido and anorgasmia)
TCAs: MOA Inhibits both norepinephrine and serotonin re-uptake transporters.
TCAs:Toxicity Used to be first line drug, but overtaken by SSRIs due to cardiac effects. Eg. Tachycardia, arrythmias, postural hypertension. Causes anti-cholinergic effects eg. constipation, blurring of vision, dry mouth, urinary retention, sedation and fatigue.
TCAs: MOA Inhibits both norepinephrine and serotonin re-uptake transporters.
TCAs:Toxicity Used to be first line drug, but overtaken by SSRIs due to cardiac effects. Eg. Tachycardia, arrythmias, postural hypertension. Causes anti-cholinergic effects eg. constipation, blurring of vision, dry mouth, urinary retention, sedation and fatigue.
Created by: Aurorahx
 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!

"Know" box contains:
Time elapsed:
Retries:
restart all cards