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Neurologic drugs
Oral Pharmacology for the Dental Hygienist
| Question | Answer |
|---|---|
| PHENYTOIN | DILANTIN tonic-clonic seizure and complex partial seizures |
| CARBAMAZEPINE | TEGRETOL OR CARBITROL tonic-clonic and partial seizures and for trigeminal neuralgia |
| OXCARBAZEPINE | TRILEPTAL momotherapy partial/mixed seizures adjuctive treatment of children and adults with refractory partial seizures |
| LEVETIRACETAM | KEPPRA partial seizures generalized tonic-clonic, adjuctive refractory |
| PHENOBARBITAL | LUMINAL alternative drug for partial seizures and tonic-clonic seizures; the drug of choice in febrile seizures in children |
| PRIMIDONE | MYSOLINE complex parital and generalized tonic-clonic seizures |
| VALPROIC ACID | DEPAKENE for complex partial seizures |
| DIVALPROEX SODIUM | DEPAKOTE for complex partial seizures |
| ETHOSUXIMIDE | ZARONTIN gerneralized absence (petit mal) |
| BENZODIAZEPINES | DIAZEPAM OR CLONAZEPAM OR LORAZEPAM drug of choice in status epilepticus |
| GABAPENTIN | NEURONTIN partial seizures adjunctive in adults and children with refractory partial seizures |
| PREGABLIN | LYRICA partial seizures adjunctive in adults and children with refractory partial seizures |
| LAMOTRIGINE | LAMICTAL partial seizures in combination with other drugs adjunctive in adults and children with refractory partial seizures |
| ZONISAMIDE | ZONEGRAN partial seizures adjuctive in refractory |
| TIAGABINE | GABITRIL adjunctive in refractory partial seizures |
| TOPIRAMATE | TOPAMAX partial/tonic-clonic seizures |
| DOPAMINE PRECURSOR carbidopa/levodopa | PARCOPA parkinson's disease moderate to severe |
| DOPAMINE PRECURSOR carbidop/levodopa/entacapone | STALEVO parkinson's disease most effective drug (only 2-5 yrs) carbidop/levodopa/entacapone |
| MAO-B INHIBITOR selegiline rasagiline | ELDEPRYL parkinson's disease use with levodopa/carbidopa AZILECT |
| COMT INHIBITOR entacapone tolcapone | COMTAN parkinson's disease used in conjuct. with the dopa's TASMAR |
| DOPAMINE AGONISTS bromocriptine | PARLODEL parkinson's disease directly activate dopamine receptors in the brain |
| DOPAMINE AGONISTS pergolide | PERMAX parkinson's disease used as adjuctive treatment to dopa's |
| DOPAMINE AGONISTS pramipexole | MIRAPEX parkinson's disease for mild to sever disease |
| DOPAMINE AGONISTS ropinirole | REQUIP parkinson's disease no special features |
| ANTICHOLINERGIC AGENTS amantadine | SYMMETREL parkinson's disease antimuscarinic; my increase dopamine activity |
| ANTICHOLINERGIC AGENTS denztropine | COGENTIN parkinson's disease muscarinic antagonists; used for tremors |
| ANTICHOLINERGIC AGENTS trihexylphenidyl | ARTANE parkinson's disease muscarinic antagonists; used for tremors |
| TRIPTANS almotriptan-Axert eletriptan-Relpax frovatriptan-Frova | newest drug for migraines. Acute |
| NON-NARCOTIC ANALGESICS acetaminophen-Tylenol aspirin,acetaminophen,caffeine-Excedrin M ibuprofen-Advil | abort migraine. Acute |
| NARCOTIC ANALGESICS codeine,acetaminophen,caffeine,butalbital- Fioricet | abort migraine. Acute |
| ERGOT ergotamine-Ergomar ergotamine,caffeine-Carfergot | abort migraine. Acute |
| ANTICONVULSANTS topiramate-Topamax valproic acid-Depakote | migraine prophylaxis |
| CALCIUM CHANNEL BLOCKERS diltiazem-Cardizem nifedipeine-Procardia verapamil-calan | migraine prophylaxis |
| BETA-BLOCKERS atenolol-Tenormin metroprolol-Lopressor propranolol-Inderal | migraine prophylaxis |
| TRICYCLIC ANTIDEPRESSANTS anitriptyline-Elavil imipramine-Tofranil Nortipytyline-Pamelor | migraine prophylaxis |
| BOTULINUM TOXIN botulinum toxin type A -Botox | migraine prophylaxis injection |
| SULFONYLUREAS-1st generation chlopropamde-Diabinese tolazamide-Tolinase tolbutamide-Orinase | stimulates release of insulin from pancreatic beta cells. use in type 2 diabetes |
| SULFONYLUREAS-2nd generation glipizide-Glucotrol glyburide-DiaBeta glimepiride-Amaryl | stimulates release of insulin from pancreatic beta cells. use in type 2 diabetes |
| BIGUANIDES metformin-Glucophage | shuts of the liver's excess glucose production |
| COMBO DRUGS Glucovance Metaglip Avandamet | shuts of the liver's excess glucose production |
| THIAZOLIDINEDIONES pioglitazone-Actos rosiglitazone-Avandia | newest agents. act to target insulin sensitivity |
| ALPHA-GLUCOSIDASE INHIBITORS acarbose-Precose miglitol-Glyset | slows postprandial carb absorption in the blood. used in type 2 diabetes that can't be teated by diet alone |
| MEGLITINIDES repaglinide-Prandin nateglinide-Starlix | increases insulin secretion from beta cells, which reduces glucose levels |
| HYPERTHYROIDISM sweating,weight loss,nervousness | propylthiouracil-PTU methimazole-Tapazole radioactive iodine-RAI beta-blockers-Propranolol iodine-Lugol's solution |
| HYPOTHYROIDISM cold,weak,tired,constipation | thyroid USP thyroxine-Levoxyl,Synthroid triiodothyronine-Cytomel |
| SYSTEMIC GLUCOCORTICOSTEROIDS Short-Acting cortisone-Cortone hydrocortisone-Cortef | anti-inflammatory effects (8-12 HRS) glucocorticosteroid |
| INTERMEDIATE ACTINGPREDNISOLONE prednisolone-Orapred,Prelone | drug of choice b/c of low cost and few side effects (12-36 hrs) glucocorticosteroid |
| LONG ACTING betamethasone-Celestone dexamethasone-Decadron | has the greatest anti-inflammatory activity (36-54 hrs) glucocorticosteroid |