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Stack #181450
GI Meds
| Question | Answer |
|---|---|
| CALCIUM CARBONATE | Tums-calcium containing antacid |
| Antacids MOA | ACT TO NEUTRALIZE ACID IN THE STOMACH (raise the PH)PROMOTE GASTRIC MUCOSAL DEFENSIVE MECHANISM BYSTIMULATING MUCUS, PROSTAGLANDIN & BICARBONATE SECRETION FROM GASTRIC CELLS |
| Antacid Side effects,MAGNESIUM PREPARATIONS | DIARRHEATOXICITYUSE WITH EXTREME CAUTION IN PATIENTS WITH RENAL FAILURE (difficult to excrete) |
| CALCIUM PREPARATIONS Antacid side effects | REBOUND HYPERACIDITY |
| Aluminum & Calcium Antacid side effects | Constipation |
| Cimetidine | Tagament-H2 Antagonist |
| Famotidine | Pepcid-H2 Antagonist |
| Ranitidine | Zantac-H2 Antagonist |
| 4 things that defend stomach lining | mucus, bicarbonate, good blood flow, and prostaglandins |
| H2 Antagonists | block H2 receptors of acid producing cells (suppress acid production) |
| Therapeutic uses of H2 antagonists | Gastric ulcers, GERD,Hypersecretory conditions (stress), Duodenal ulcers, Upper GI bleeds |
| Adverse effects of Cimetidine (Tagement) | Impotence and Gynecomastia |
| Proton Pump Inhibitors (PPIs) | prevents proton pump from moving hydrogen ions out of parietal cells and into the stomach; blocks all acid secretion |
| Esomeprazole | Nexium -PPI |
| Lansoprazole | Prevacid- PPI |
| Omeprazole | Prilosec-PPI |
| Therapeutic uses of PPIs | GERD, Erosive esophagitis, duodenal ulcers, active gastric ulcers |
| Sucralfate (Carafate) | cytoprotective agent (mucuosal protectant), forms protective barrier over ulcers and limits access of pepsin and gastric acid to these ulcers |
| Therapeutic uses of Sucralfate (Carafate) | Stress ulcers, Erosions, Peptic Ulcer disease |
| ALUMINUM HYDROXIDE | Amphojel |
| Docusate Sodium (Colace) | Surfacant Laxative-Stool softnerwetting agent to soften stool |
| Psyllium (Metamucil) | Bulf forming laxativeabsorbs water to increase bulk |
| Senna (Senokot) | Stimulant laxativeincreases peristalsis via nerve stimulation in the colon |
| Magnesium hydroxide (MOM) | Osmotic laxativeincreases water content of stool |
| Adverse effect of stool softners | Abdominal cramping |
| Adverse effect of bulk forming laxatives | Gas formation |
| Adverse effect of stimulant laxatives | Malaborption |
| Adverse effect of osmotic laxatives | Electrolyte imbalance (dehydration) |
| Promethazine (Phenergan) | Antiemetic-antihistimine, blocks histamine receptors |
| Therapeutic uses of Promethazine (Phenergan) | Motion sickness, N/V |
| Ondansetron (Zofran) | Antiemetic-serotonin blocker, blocks serotonin receptors in GI tract and vomiting center in the medulla |
| Therapeutic uses of Ondansetron (Zofran) | N/V associated with Chemotherapy and post op |