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P1 Top 200

Group 4

BrandGenericIndicationFormDoseMOA
Bactroban Mupirocin Topical infection Ointment (nasal), cream PEDS & ADULT: tid Inhibition of protein synthesis
Cipro Ciprofloxacin Sinusitis, prostatitis, bronchitis, bone and joint infections, abdominal infections, diarrhea Tablet (ER), ear & eye drops, IV, reconstitution 250 to 750 mg BID; 10 to 20 mg/kg BID Inhibition of topoisomerase II enzymes
Cleocin Clindamycin Bacterial vaginosis Cream (pregnant only), vaginal suppository, IV, lotion, gel, swab, external solution, external foam 150-450 mg q6h Binds to 50S preventing bacterial protein synthesis
Diflucan Flucanazole Candidiasis, meningitis Tablet, IV, reconstitution 50 to 400 mg QD; 6 to 12 mg/kg QD Interferes with P450 activity
Flagyl, Metrocream, Metrogel Metronidazole Bacterial vaginosis Tablet (ER), capsule, IV, cream, lotion, gel (external/vaginal) 0.75% (37.5 mg) intravaginally BID x 5 days; 1.3% (65 mg) intravaginally once Inhibition of protein synthesis
Keflex Cephalexin Otitis, bronchitis, bone infections, skin infections, UTI Tablet, capsule, reconstitution 250 mg q6h; 25 to 50 mg/kg/day Inhibits bacterial wall synthesis
Levaquin Levofloxacin Sinusitis, bronchitis, prostatitis, pyelonephritis, skin infections, plague, anthrax, UTI, pneumonia Tablet, oral & IV solution, eye drops 250 to 750 mg/day; 8 mg/kg BID Inhibition of topoisomerase II enzymes
Macrobid Nitrofurantoin Macrocrystals UTI Capsule, suspension 50 to 100 mg QID; 5 to 7 mg/kg/day Inhibits protein and bacterial wall synthesis
Omnicef Cefdinir Sinusitis, otitis, bronchitis, pharyngitis, skin infections, pneumonia Capsule, reconstitution 600 mg x 10 days; 14 mg/kg x 10 days Inhibits bacterial wall synthesis
Penicillin VK, Penicillin G Penicillin VK, G Fever, sinusistis, pharyngitis, heart disease, venereal infections, strep, staph, pneumonia Tablet, reconstitution (oral & injection) VK: 125 to 500 mg q6-8h; G: 1.2 mil u/mo; 50,000 u/kg single dose Inhibits bacterial wall synthesis
Periostat, Vibra-tabs, Doryx, Monodox, Oracea Doxycycline Fever, sinusitis, skin & eye inf., sexually transmitted inf., Rickettsial, Vincent, Yaws, & Zoonotic inf., gram-negative inf., actinomycosis, intestinal amebiasis, anthrax, cholera, clostridium, listeriosis, malaria prophylaxis, rosacea Tablet (DR), capsule (DR), IV, reconstitution, syrup 100 mg BID Inhibition of protein synthesis
Solodyn, Dynacin, Minocin Minocycline Periodontitis Tablet (ER), capsule, IV 45 to 200 mg/day; 2 mg/kg BID Inhibition of protein synthesis
Sovaldi Sofosbuvir Hepatitis C Tablet 400 mg QD Antiviral prodrug
Valtrex Valacyclovir Cold sores, herpes, chickenpox Tablet 1 to 2 g/day; 20 mg/kg tid x 5 days Inhibits DNA synthesis and viral replication.
Zithromax, ZPAK Azithromycin Sinusitis, otitis, pharyngitis, urethritis, cervicitis, skin infections, COPD, CAP, MAC tx, genital ulcer Tablet, eye drops, packet, reconstitution (IV) 500 mg/day; 12 mg/kg/day Binds to 50S preventing bacterial protein synthesis
Zovirax Acyclovir Herpes, chickenpox Tablet, capsule, suspension, IV, ointment, cream 200 to 800 mg BID x 5 to 10 days; 20 mg/kg QID x 5 days Inhibits DNA synthesis and viral replication.
Amoxil, Trimox, Moxatag Amoxicillin Skin infections, UTI, ENT infections, LRI, gonorrhea, H. pylori Tablet (chewable, ER), capsule, reconstitution 500 mg BID; 25 mg/kg/day Inhibits bacterial wall synthesis
Ancef Cefazolin Endocarditis, bronchitis, biliary infection, bone and joint infection, genital infection, UTI, skin infections, perioperative prophylaxis, septicemia IV reconstitution 750 mg to 6 g QD Inhibits bacterial wall synthesis
Augmentin Amoxicillin/Clavulanic Acid Sinusitis, otitis, bronchitis, skin infections, UTI, pneumonia Tablet (ER), reconstitution 500 mg BID; 200 to 400 mg chewable tabs Beta-lactamase inhibitor
Bactrim, Septra Sulfamethoxazole/Trimethoprim Bronchitis, otitis, enteritis, UTI, PCP, diarrhea Tablet, IV, suspension 800/160 mg BID; 40/8 mg/kg BID SMX: Inhibition of dihydrofolic acid formation. TMP: Inhibition of dihydrofolic acid reduction.
Created by: sdeck86
 

 



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