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Chapter 8

Drugs for Central Nervous System Disorders

QuestionAnswer
Fairly common neurological disorder characterized by sudden and recurring seizures Epilepsy
The three states of a neuron Resting, firing, returning to rest
The two neurotransmitters that play the greatest role in seizures GABA and Glutamate
The two major types of seizures Partial and Generalized
The single most important concept in treating epilepsy Monotherapy
Serious disorder involving continuous tonic-clonic convulsions, with or without a return to consciousness, that last at least 30 minutes. Can cause brain damage or death Status Epilepticus
The drug of choice for status epilepticus Diazepam (Valium) IV
The only indication for this schedule IV benzodiazepine is prophylaxis of seizures Clonazepam (Klonopin)
This popular drug is used as an adjunct in epilepsy therapy and is also used for neuropathic pain, bipolar disorder, migraine prevention, hot flashes, MS, ADD, and alcohol withdrawal Gabapentin (Neurontin)
This drug has a black box warning about fatal rashes Lamotrigine (Lamictal)
This drug is often used to treat seizures induced by alcohol withdrawal Lorazepam (Ativan)
This anticonvulsant is a schedule V because it can cause euphoria and withdrawal Pregabalin (Lyrica)
The three characteristic signs of this disease are tremors while resting, rigidity, and akinesia Parkinson's Disease
No definitive tests exist for this disease, so it's diagnosed almost exclusively by its symptoms Parkinson's Disease
This drug is considered to be the gold standard in Parkinson's drug therapy Levodopa
This drug can be used as an antiviral to treat influenza and can also be used to treat Parkinson's disease Amantadine (Symmetrel)
The most commonly used drug to treat Parkinson's disease Carbidopa-Levodopa (Sinemet)
A wide fluctuation between abnormally increased and abnormally diminished motor function, present in Parkinson's patients after about five years of levodopa therapy On-off phenomenon
This disease is also known as Lou Gehrig's disease Amyotrophic lateral sclerosis (ALS)
The only drug approved to treat ALS. It improves survival by approximately three months Riluzole (Rilutek)
Drugs used to treat this autoimmune disease are very expensive Multiple Sclerosis
A degenerative disorder of the brain that leads to progressive dementia and changes in behavior and personality. Depression is part of the disease profile. Alzheimer's disease
Most of the drugs used to treat ADD or ADHD belong to this drug class Amphetamines (Schedule II)
The only nonstimulant medication used to treat ADHD in patients 6 years and older Atomoxetine (Strattera)
The drug of choice to treat ADHD or ADD methylphenidate
Generic for Ativan lorazepam
Generic for Topamax topiramate
Generic for Concerta methylphenidate
Generic for Lamictal lamotrigine
Generic for Klonopin clonazepam
Generic for Aricept donepezil
Generic for Sinemet carbidopa-levodopa
Generic for Tegretol carbamazepine
Generic for Dilantin phenytoin
Generic for Neurontin gabapentin
Generic for Keppra levetiracetam
Generic for Depakote divalproex
Generic for Valium diazepam
Generic for Requip ropinirole
Generic for Adderall dextroamphetamine-amphetamine
Created by: sarakiefer