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Chapter 5

Therapy for fungal and viral infections

Single-celled organism similar to a human cell in that it has a defined nucleus Fungus
A common target of fungal infections Fingernails and toenails
A regimen of dosing one week per month, commonly used for treating fungal nail infections Pulse dosing
This IV drug is used for blood-borne, life-threatening fungal infections. Prophylaxis with APAP and/or diphenhydramine and antiemetics is often necessary. amphotericin B (Fungizone)
This drug is most often used in liquid form with the directions to "swish and swallow" to treat thrush or a yeastlike fungal growth in the mouth nystatin (Mycostatin)
This antifungal capsule should be taken with pop or orange juice because absorption is improved by increasing stomach acidity itraconazole (Sporanox)
This drug, an alternative to amphotericin B, can cause liver toxicity and blurred vision. voriconazole (VFEND)
A minute infectious agent that is much smaller than a bacterium and cannot reproduce on its own Virus
A virus that quickly resolves with no latent infection is known as this. An example is the common cold. Acute viral infection
An infection that has a protracted course with long periods of remission interspersed with recurrence. An example is herpes. Chronic viral infection
A drug that limits the progression of HIV or other retrovirus infections antiretroviral
A drug that prevents HIV from entering the immune cells fusion inhibitor
The ability of a virus to lie dormant and then, under certain circumstances, reproduce and again behave like an infective agent, causing cell damage latency
The administration of antiretrovirals after exposure to HIV post-exposure prophylaxis (PEP)
A compound that, on administration and chemical conversion by metabolic processes, becomes as active pharmacological agent prodrug
A small lozenge troche
Preventing infection by providing immunity vaccination
Many antiviral drugs will end with this suffix -vir
Many antifungal drugs will end with this suffix -azole
This drug is can be used to treat influenza A and Parkinson's Disease. amantadine (Symmetrel)
One of the first drugs, an NRTI, developed specifically for the treatment of HIV AZT (Retrovir)
This NNRTI may induce vivid dreams, nightmares, and hallucinations, and has been abused for it's hallucinogenic properties efavirenz (Sustiva)
Side effects associated with this class of HIV drugs include a redistribution of body fat, humped back, facial atrophy, breast enlargement, and hyperglycemia Protease inhibitors
Created by: sarakiefer