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seizures

pharm122

QuestionAnswer
anticonvulsant is a drug that terminates convulsive seizures
antiepileptic used prophylactically to reduce or prevent epileptic seizures
What are some considerations regarding anti-seizure drug therapy? CNS depression can lead to respiratory depression, most have a low therapeutic index (check serum levels), lots of drug interactions, class D pregnancy class, decrease oral contraceptives, folic acid deficiency
What are the overall goals for anti-seizure therapy? suppress neuronal firing enough to prevent repetitive or abnormal firing AND/OR increase the electrical threshold for firing to prevent epileptics from crossing the threshold as often (succanimides).
What is GABA? GABA is a primary inhibitory neurotransmitter that works in the brain
What do some anti-seizure meds do to GABA? Anti-seizure meds will enhance GABA actions.
What is the drug category of choice for status epilepticus? Benzodiazapines (lorazepam Ativan)
What are some adverse effects for Phenytoin (Dilantin)? Adverse side effects for hydantoins include dizziness, ataxia, visual disturbances, dysrhythmias, peripheral neuropathy, agranulocytosis, and aplastic anemia, gingival hyperplasia
What are some nursing considerations for Phenytoin (Dilantin)? Nursing considerations include CBCs, monitor serum levels, interact with many drugs, good oral hygiene and frequent trips to dentist.
Created by: amyeva22