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antibiotics pharm
pharmacy tech antibiotics
| Question | Answer |
|---|---|
| bacteria | microorganisms that cause infection |
| bactericidal agent | kills the invading organisms |
| bacteriostatic agent | inhibits the growth or multiplication of bacteria |
| cocci shape | round |
| bacilli shape | rods |
| spirochetes shape | spiral |
| block protein formation | macrolides, tetracyclines, aminoglycosides |
| inhibit cell wall formation | penicillins, cephalosporins |
| prevents folic acid synthesis | sulfonamides |
| prevents cross contamination | swab counting tray with alcohol between drugs |
| antibiotics are absorbed faster by: | taking on an empty stomach |
| types of antibiotics that should be taken with food | nitrofurantoin, cefuroxime |
| antimicrobial resistance caused by | overuse, misuse |
| label to decrease antimicrobial resistance | take all of this medication |
| sulfonamides | nitrofurantoin, sulfamethoxazole-trimethoprim, sulfisoxazole |
| do not do with sulfonamides | take on empty stomach, drink alcoholic beverages |
| therapeutic uses of sulfonamides | UTI, Otitis media, Ulcerative colitis, lower respiratory infections, prophylaxis in pneumocystis carinii pneumonia |
| sulfonamides side effects | rash, n/v, fever, jaundice, blood complications, kidney damage |
| sulfonamides dispensing issues | avoid sun, maintain fluid intake |
| penicillins prevent bacteria from | forming rigid cell wall |
| penicillin has low | toxicity |
| penicillins | amoxicillin, amoxicillin-clavulanate, ampicillin-sulbactam, carbenicillin |
| therapeutic use of penicillins | abscesses, beta strep, meningitis, pneumonia, respiratory infections, tooth and gum infections, vd, endocarditis |
| penicillins side effects | diarrhea, allergies in 7-10% |
| penicillins dispensing issues | take on empty stomach, acids in fruit juices or colas could deactivate the drug |
| cephalosporins | similar to penicillin |
| allergic to penicillin | 10% chance of being allergic to cephalosporin |
| first gen cephalosporins | community acquired infections, mild to moderate infections |
| second generation cephalosporins | used for otitis media in kids, respiratory infections, UTI |
| third generation cephalosporins | active against wide spectrum gram neg organisms, once a day dosing, |
| side effects cephalosporins | same as penicillin, lower frequency than many other antibiotics |
| tetracyclines | broad spectrum bacteriostatic antibiotics, bind to ribosomes |
| therapeutic uses of tetracyclines | acne, chronic bronchitis, lyme disease, mycoplasma pneumoniae,rickettsia, vd, travelers diarrhea |
| side effects of tetracyclines | gi upset, n/v |
| tetracycline dispensing issues | avoid antacids, photosensitization, avoided by pregnant women and children, expired drugs are dangerous |
| macrolides | inhibit protein synthesis combine with ribosomes, used to treat pulmonary infections |
| macrolides treat | chlamydia, beta strep, h influenzae, legionnaire's disease, |
| macrolides dispensing issues | take with food |
| ketolides | bind with ribosomes, treats infections in lungs and sinuses, treats bacteria resistant to macrolides |
| quinolones | bacteriocidal |
| therapeutic use of quinolones | bone and joint infections caused by gram neg organisms, infectious diarrhea, ophthalmic infections, uri, uti |
| quinolone side effects | gi, n/v, dizziness, unpleasant taste, joint swelling, tendon injuries |
| quinlone dispensing issues | antacids interfere with absorption, avoid sun,do not give with theophylline |
| aminoglycosides | treat serious infections, binds to ribosomes |
| aminoglycosides side effects | nephrotoxicity, ototoxicity, tinnitus, equilibrium problems, permanent deafness. |
| Independent antibiotic class uses | acne, anaerobic pneumonia, bone infections, bowel infections, female infections, intra abdominal infections |
| adjunct in treating sepsis | xigris |