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antibiotics pharm

pharmacy tech antibiotics

bacteria microorganisms that cause infection
bactericidal agent kills the invading organisms
bacteriostatic agent inhibits the growth or multiplication of bacteria
cocci shape round
bacilli shape rods
spirochetes shape spiral
block protein formation macrolides, tetracyclines, aminoglycosides
inhibit cell wall formation penicillins, cephalosporins
prevents folic acid synthesis sulfonamides
prevents cross contamination swab counting tray with alcohol between drugs
antibiotics are absorbed faster by: taking on an empty stomach
types of antibiotics that should be taken with food nitrofurantoin, cefuroxime
antimicrobial resistance caused by overuse, misuse
label to decrease antimicrobial resistance take all of this medication
sulfonamides nitrofurantoin, sulfamethoxazole-trimethoprim, sulfisoxazole
do not do with sulfonamides take on empty stomach, drink alcoholic beverages
therapeutic uses of sulfonamides UTI, Otitis media, Ulcerative colitis, lower respiratory infections, prophylaxis in pneumocystis carinii pneumonia
sulfonamides side effects rash, n/v, fever, jaundice, blood complications, kidney damage
sulfonamides dispensing issues avoid sun, maintain fluid intake
penicillins prevent bacteria from forming rigid cell wall
penicillin has low toxicity
penicillins amoxicillin, amoxicillin-clavulanate, ampicillin-sulbactam, carbenicillin
therapeutic use of penicillins abscesses, beta strep, meningitis, pneumonia, respiratory infections, tooth and gum infections, vd, endocarditis
penicillins side effects diarrhea, allergies in 7-10%
penicillins dispensing issues take on empty stomach, acids in fruit juices or colas could deactivate the drug
cephalosporins similar to penicillin
allergic to penicillin 10% chance of being allergic to cephalosporin
first gen cephalosporins community acquired infections, mild to moderate infections
second generation cephalosporins used for otitis media in kids, respiratory infections, UTI
third generation cephalosporins active against wide spectrum gram neg organisms, once a day dosing,
side effects cephalosporins same as penicillin, lower frequency than many other antibiotics
tetracyclines broad spectrum bacteriostatic antibiotics, bind to ribosomes
therapeutic uses of tetracyclines acne, chronic bronchitis, lyme disease, mycoplasma pneumoniae,rickettsia, vd, travelers diarrhea
side effects of tetracyclines gi upset, n/v
tetracycline dispensing issues avoid antacids, photosensitization, avoided by pregnant women and children, expired drugs are dangerous
macrolides inhibit protein synthesis combine with ribosomes, used to treat pulmonary infections
macrolides treat chlamydia, beta strep, h influenzae, legionnaire's disease,
macrolides dispensing issues take with food
ketolides bind with ribosomes, treats infections in lungs and sinuses, treats bacteria resistant to macrolides
quinolones bacteriocidal
therapeutic use of quinolones bone and joint infections caused by gram neg organisms, infectious diarrhea, ophthalmic infections, uri, uti
quinolone side effects gi, n/v, dizziness, unpleasant taste, joint swelling, tendon injuries
quinlone dispensing issues antacids interfere with absorption, avoid sun,do not give with theophylline
aminoglycosides treat serious infections, binds to ribosomes
aminoglycosides side effects nephrotoxicity, ototoxicity, tinnitus, equilibrium problems, permanent deafness.
Independent antibiotic class uses acne, anaerobic pneumonia, bone infections, bowel infections, female infections, intra abdominal infections
adjunct in treating sepsis xigris
Created by: cbiondillo



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