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PTCE
| Question | Answer |
|---|---|
| Which antiviral drug is used in the treatment and prophylaxis of influenza A and B? | zanamivir (Relenza) |
| Urticaria and pruritus as examples of... | allergic reactions |
| Which of the following drugs acts by preventing the HIV virus from entering immune cells? | enfuvirtide (Fuzeon) |
| A pharmacy has an inventory value of $145,000.00 per week with product costs of $36,000.00. The goal is to have the days' supply at 25 days. What will inventory need to be dropped by to attain this goal? | $15,429.00 |
| There are 120 mg of triamcinolone powder in 4 oz of cream. What is the percentage strength of the cream? | 0.1% w/v |
| Which of the following drugs is NOT used in the treatment of asthma? | propranolol (Inderal) |
| What is meant by a leading zero? | a zero before the decimal on a number less than one |
| Which of the following should the pharmacy technician used to determine the stability of a manufactured sterile product? | expiration dating |
| The environment in which a pharmacy technician compounds sterile products is called a | clean room |
| How is pulse dosing of antifungal drugs for nail infections utilized? | Pulse doses are usually given for 1 week per month |
| How many teaspoonfuls are in a quart? | 192 tsp |
| What did the Food, Drug, and Cosmetic Act of 1938 require of new drugs before they could be marketed in the U.S? | safety |
| What is the term for the difference between the selling price and the purchase price of a drug? | gross profit |
| In what major way does COPD differ from asthma? | Asthma primarily affects inspiration; emphysema primarily affects expiration |
| An amp of calcium chloride is 10% and contains 10 mL. How many grams of calcium chloride are in each amp? | 1g |
| which of the following drug is used to treat respiratory distress syndrome (RDS) | beractant (Survanta) |
| What antibiotic (or combination) may be used to treat urinary tract infections (UTIs) | All choices are correct |
| What volume is 60 minims equivalent to? | 1 fluidram |
| Which drug or class of drugs may be used to treat heart failure? | All of the choices may be used in the treatment of heart failure (digoxin, diuretics, angiotensin converting enxyme (ACE) inhibitors) |
| When mixing solids and liquids, how can the solid be made to dissolve faster? | heat the liquid if stable |
| According to the Drug Enforcement Administration (DEA), which of the following drugs currently has the least potential for abuse? | phenobarbital |
| What is an advantage of commercially prepared frozen IV solutions? | They result in less wastage |
| A 1:500 solution is ordered, and you have in stock a 5% solution, a 2% solution, and a 0.2% solution. Which one will you use? | 0.2% |
| What is the most frequent form of bacterial resistance to antibiotics? | destruction of antibiotic by bacterial enzymes |
| Which second-generation (atypical) antipsychotic drug carries a Black Box warning because the drug may cause a serious reduction in white blood cells? | clozapine (Clozaril) |
| What drug is used to treat syphilis and is the only agent active against growing bacteria? | penicillin G Benzathine (Bicillin L-A) |
| Why is mycophenolic acid (Myfortic) used in renal transplant patients? | as an immunosuppresant |
| What device is used to assess the severity of asthma? | peak flow meter |
| What class of drugs is commonly used to treat benign prostatic hyperplasia (BPH)? | alpha adrenergic blockers |
| With what clinical condition does the patient experience chest heaviness, pressure, tightness, choking, a squeezing sensation, as well as sweating, dizziness, and dyspnea? | angina |
| If there is a 1 g of sodium bicarbonate in 1 L of water, what percentage is the solution? | 0.1% |
| What is anticipatory compounding? | preparing an excess amount of a prescription |
| Which of the following drugs is indicated only for long-term maintenance therapy of bronchospasms associated with emphysema and bronchitis? | tiotropium (Spiriva) |
| What is the term for the difference between the selling price of a product and the overall cost of an item? | net profit |
| How many tablespoonsful are in a 12 fl oz bottle of milk of magnesia? | 24 tbsp |
| Pick a product to fill a medication order for atropine 0.5 mg/mL injectable | 1:2000 |
| If the overall cost for a month of birth control pills is $29.95 and the selling price is $32.50, what is the percent profit? | 8.5% |
| For which class of antidepressant drugs should the patient be given instructions on food and other drugs to be avoided because of the potential for a severe hypertensive crisis? | monoamine oxidase inhibitors (MOAIs) |
| What size of filter needle should be used to withdraw a hazardous agent from an ampule? | 5 micron |
| What term describes tumors that have detached and relocated to form tumors in other parts of the body? | metastatic tumors |
| What recombinant DNA agent increases red blood cell production? | epoetin alpha (Epogen, Procit) |
| What drug is equivalent to granulocyte colony-stimulating factor (G-CSF)? | filgrastim (Neupogen) |
| What is most often used in the pharmacy for estimating beyond-use dating? | UPS<795> |
| What drug stimulates insulin release from pancreatic beta cells? | repaglinide (Prandin) |
| A mother has an oral syringe that is marked with milliliters. The dose for her child is 1 3/4 tsp. How many milliliters should she administer? | 8.8 mL |
| Which federal aw required the manufacturer to prove that a drug was safe before it could be marketed in the United States? | Federal Food, Drug, and Cosmetic Act (1938) |
| Which of the following is NOT an antiemetic? | Morphine |
| A balance with a least weighable quantity of 80 mg is used to compound a prescription with 15 mg of drug in sterile water. What is the smallest factor that may be used to calculate the amount of active drug to be weighed? | 6 |
| with what bacterial pathway do sulfonamides interfere? | folic acid biosynthesis |
| which herbal remedy has been shown to relieve twelve symptoms that may be typical of cerebral insufficiency in elderly persons? | ginkgo |
| what other term is sometimes used instead of antipsychotics? | neuroleptics |
| what chemotherapeutics agents is used to treat Hodgkin disease? | procarbazine (Matulane) |
| A hospital pharmacy buys twelve new computers at $1250.00 each. They are estimated to last 5 years and have a disposal value of $100.00 each. What is the annual depreciation rate for the twelve computers? | $2,760.00 |
| In large hospital pharmacies, which area of the sterile compounding lab should have an air quality of ISO Class 7 or lower? | buffer area |
| The pharmacy technician uses a diluent powder to make a pediatric | capsule |
| Where in the body does a drug's first-pass effect occur? | in the liver |
| What is a symptom of hypothyroidism? | apathy and easy fatiguing |
| If multiple topical formulations (creams, ointments, and gels) of the same steroid are available; in general, which is the most potent? | ointment |
| The gradual combining of drugs using a mortar and pestle is called | geometric dilution |
| Which unit of measure in the apothecary system is equivalent to either 60 mg or 65 mg, depending on the manufacturer? | grain |
| How long can a medium-risk CSP be stored in the refrigerator? | 4 days |
| If the selling price for Cymbalta is $66.69 for 30 capsules and the pharmacy pays $156.98 for 100 capsules, what is the markup rate? | 42% |
| Which document is unique for each prescription? | compounding log |
| What can assist the pharmacy technician in resolving an ethical dilemma that presents itself in pharmacy practice? | all choices are correct |
| Which is the term to describe medication administered by injection and not by the gastrointestinal tract? | parenteral |
| Diabetics must be aware that the oral suspension of ____ has a high sugar content. | cefdinir (omnicef) |
| Which of the following dosage forms may be administered by more than one (oral vs. parenteral vs. topical) route? | solutions |
| What term describes a thickening of the heart muscle? | myocardial hypertrophy |
| which drug listed below can cause hypoglycemia? | ethanol |
| Which of the following drugs is classified as a non-nucleoside reverse transcriptase inhibitor (NNRTI), used in the treatment of HIV? | efavirenz (Sustiva) |
| If the AWP of a drug is $7.35/tablet, the insurance company pays $75.25 for 10 tablets, and the dispensing fee is $5.25, what is the discount from AWP per the contract? | 4.76% |
| What is the most frequent form of bacterial resistance to antibiotics? | destruction of antibiotic by bacterial enzymes |
| A monthly fee paid to a pharmacy to cover all of a patient's prescriptions for the month is called a | capitation fee |
| What is the term for a dose form prepackaged or repacked and ready for administration to a particular patient at particular time? | unit dose |
| What drug below is a phosphodiesterase inhibitor used for IV therapy of congestive heart failure and calcium channel blocker intoxication? | milrinone(Primcor) |
| What is the first oral therapy for interstitial cystitis? | pentosan polysulfate sodium (Elmiron) |
| Which pair of anticonvulsants is most likely to interact with other drugs a patient may be taking? | phenobarbital (Luminal) and phenytoin (Dilantin) |
| Which is the term to described medication administered by injection and not by the gastrointestinal tract? | parenteral |
| which of the following is not an appropriate way to represent 20%? | 0.02 |
| What is a potential way in which anitepileptic medications can interact with each other and with other drugs? | They can alter the metabolism of other drugs |
| Which of the following antipsychotic drugs is classified today as being "atypical"? | olanzapine (Zyprexa) |
| Which drug listed below is one of a new class of anit-Parkinson drug that inhibits catechol-o-methyl transferase 9COMT) and is used to enhance the activity of levodopa? | entacapone (Comtan) |
| Which of the following oral hypoglycemic agents acts by interfering with carbohydrate metabolism and glucose absorption? | acarbose (Precose) |
| A 3 month supply (90 tablets) of Lipitor 10mg is sold for $270.00 to the patient. The pharmacy's purchase price for 100 tablets is $257.59. What is the gross profit? | $38.17 |
| Which of the following is a C-IV opioid/narcotic? | butorphano |
| Percentage of error is representative of the | accuracy of a measurement |
| Once a patient has opened an ophthalmic ointment, how long may the unused medication be safely kept? | 30 days |
| Which of the following drugs is an inhibitor of angiotensin converting enzyme (ACE) and is used to treat congestive heart failure (CHEF) and hypertension? | lisinopril (Prinivil, Zestril) |
| Which of the following lipid-lowering agents interferes with the absorption of cholesterol from the intestines? | ezetimibe (Zetia) |
| What drug listed below is approved to treat genital and perianal warts? | imiquimod (Aldara) |
| What risk factor associated with Coumadin would require a MedGuide? | may cause patient to bleed easily |
| Which of the following antihypertensive drugs is also available in a topical form that can be used to treat baldness? | minoxidil |
| Folic acid is available in 10 mL vials of 5 mg/mL concentration. The patient needs to get 1 mg daily. How much diluent should be added to the 10 mL of concentrate to make 1 mg/mL product? | 40 mL |
| What is the smallest particle removed by the HEPA filter in a horizontal LAFW? | 0.3 micron |
| What analgesic drug binds centrally to opioid receptors and also inhibits the reuptake of norepinephrine (NE) and serotonin (5-HT) into nerve endings? | tramadol (Ultram) |
| Phenobarbital is a drug that enhances drug metabolism by what process? | metabolic induction |
| Which unit of measure in the apothecary system is equivalent to either 60 mg or 65 mg, depending on the manufacturer? | grain |
| Which of the following drugs, used to treat frequent urination, is available as a transdermal patch> | oxybutin (Ditropan, Oxytrol) |
| Which statement regarding linezolid is INCORRECT? | It should be stored in a clear glass container |
| What is the first drug approved for the specific indication of sepsis? | drotrecogin alfa |
| What drug used to treat cystic fibrosis destroys the DNA of leukocytes that accumulate in mucus? | dornase alfa (Pulmozyme) |
| Which of the following drugs used to treat gout interferes with leukocytes, reducing their mobility and joint phagocytosis? | colchicine |
| Which of the following drugs used to treat duodenal ulcers acts as a coating agent? | sucralfate (Carafate) |
| Which of the following is an antichoinergic drug used to treat the extrapyramidal side effects of antipsychotic therapy? | benztropine (Cogentin) |
| What percentage of patients allergic to penicillins are also allergic to cephalosporins? | 1 |
| What is an example of a 'loop' diuretic? | furosemide (lasix) |
| What is the drug of choice for preeclampsia and eclampsia? | magnesium sulfate |
| How can you determine if a PN solution containing lipids has cracking? | by adding hydrochloric acid |
| What is the most common error in dispensing or administering a medication? | incorrect drug identification |
| For the treatment of hepatitis, which drug listed below is an interferon linked with branched polyethylene glycol (PEG) molecule in order to allow once weekly dosing? | peginterferon alfa-2a (Pegasys) |
| Which tricyclic antidepressant (TCA) is used primarily in children for bedwetting? | imipramine (Tofranil) |
| What is the most common immunoglobulin? | IgG |
| The Anabolic Steroid Act of 1990 | limits the number of refills on anabolic steroid prescriptions |
| What is the only antipsychotic drug to have a ceiling dose, above which it may affect vision? | thioridazine |
| what substances mediate pain, fever, and inflammation? | prostaglandins |
| convert 2 apothecary pound to ounces | 24 ounces |
| What antispasmodic agent must be dosed twice daily but does not cause drowsiness, because it does not enter the brain? | trospium (Sanctura) |
| A patient has a prescription for triamcinolone cream 0.01%, dispense 3 oz. How many grams are dispensed? | 90 g |
| A graduate's smallest measurable quantity is 20 mL. How much diluent will be needed to accurately measure 8 mL of active ingredient if a factor of 3 is used? | 48 mL |
| Which of the following drugs is a calcium channel blocker? | amilodipine (Norvasc) |
| Which of the following drugs may be used to minimize the side effects of antipsychotic drugs? | All choices are correct (diphenhydramine, benztropine, and meclizine) |
| What term is used when patients are taking multiple medications simultaneously? | polypharmacy |
| An asthma attack consists of how many phases or responses? | 2 |
| A class of drugs for which doses are calculated according to body surface area is... | antineoplastics |
| When this drug is dispensed, a "Do not drink alcohol" sticker must be attached to the container | metronidazole |
| What is the accepted abbreviation for morphine sulfate? | None of the above |
| How do salicylates reduce fever? | increasing blood flow to the skin |
| What form of angina is characterized by coronary artery spasm? | variant angina |
| What system, other than the respiratory system, is most impacted by cystic fibrosis? | gastrointestinal |
| What term describes a chemical that destroys bacteria but not necessarily spores? | germicide |
| Which of the following drugs is used for chemotherapy-induced emesis and frequently causes headaches in patients treated with it? | ondansetron (Zofran) |
| What is the primary side effect when beta (adrenergic) blockers are used to treat angina? | bradycardia |
| What is the name of the calcuation used to find the final concentration created when two or more ingredients of known concetration are added together? | alligation medial method |
| When must a compounding pharmacy apply for a manufacturing license? | if it sells directly to health professionals |
| Why should teithromycin (ketek) be used to treat ONLY penicillin- and macrolide-resistant strep pneumonia? | it may cause arrhythmias (irregular heartbeats), which can be potentially life threatening |
| Which drug listed below is used to treat Parkinson's disease? | levodopa (Dopar) |
| Which drug listed below is used to treat active Crohn disease and ulcerative colitits,but is usually reserved for moderate-to-severe cases. | infliximab (Remicade) |
| Which drug, used to treat osteoporosis, has estrogen effects on lipids and bone but inhibits other estrogen receptors? | roloxifene (Evista) |
| Which of the following classes of drugs should be avoided in men with BPH? | calcium channel blockers |
| what is the accepted abbreviation for morphine sulfate? | none of the above |
| When taking which of the following antibiotics (or combinations) should patients apply sunscreen? | ciprofloxacin (Cipro) |
| What class of drugs used to treat hypertension,angina,cardiac arrhythmias, and migraine headaches are contraindicated in asthma patients? | beta blockers |
| What is a goal of balanced anesthesia? | all of the choices are correct (amnesia, relaxed musclesm adequate ventilation, controlled pain) |
| Which of the following drugs may be used to minimize the side effects of antipsychotic drugs? | all of the choices may be used. (diphenhydramine, meclizine, benztropine) |
| Which of the antiviral drugs listed below is also effective in treading patients with Parkinsonism? | amatadine (Symmetrel) |
| Which of the following drugs is NOT a selective serotonin reuptake inhibitor? | amitriptyline (Elavil) |
| Which of the following antihypertensive drugs is also available in a topical form that can be used to treat baldness? | minoxidil |