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Top 200 #2

BrandGenericClassIndicationsRoute/Dose FormAdult/Ped. DosingMOA
Aciphex Rabeprazole PPI (proton pump inhibitor) GERD, Duodenal Ulcer Disease Oral; Tablet: 20mg ADULT: 20-60mg QD-BID PED: 1-11YO: 5-10mg QD 12YO+: 20mg QD Suppresses gastric secretion by inhibiting the gastric H+, K+ ATPase at the secretory surface of parietal cells
Dexilant Dexlansoprazole PPI (proton pump inhibitor) Esophagitis, GERD, Pyrosis (heartburn) Oral; Delayed-release capsule: 30 or 60mg ADULT: 30-60mg QD PED: N/A Suppresses gastric secretion by inhibiting the gastric H+, K+ ATPase at the secretory surface of parietal cells
Nexium Esomeprazole PPI (proton pump inhibitor) GERD, Duodenal Ulcer Disease, Gastric Ulcer Oral, IV; Delayed-release Caps: 20 or 40mg Delayed-release powder for susp: 2.5, 5, 10, 20, 40mg Powder for inj: 20 or 40mg ADULT: 20-40mg QD PED: 1mo-1YO: 0.5mg/kg QD 1-17YO: 10-20mg QD for 8 wks Suppresses gastric secretion by inhibiting the gastric H+, K+ ATPase at the secretory surface of parietal cells
Prevacid Lansoprazole PPI (proton pump inhibitor) Duodenal Ulcer Disease, Gastric Ulcer, Esophagitis, GERD Oral; Tablets or Solutabs: 15 or 30mg ADULT: 15-30mg QD PED: 1-17YO: 15-30mg QD Suppresses gastric secretion by inhibiting the gastric H+, K+ ATPase at the secretory surface of parietal cells
Prilosec Omeprazole PPI (proton pump inhibitor) GERD, Duodenal Ulcer Disease, Stress Ulcer, Gastric Ulcer, Esophagitis Oral; Delayed-release granules for susp: 2.5 or 10mg Delayed-release Caps: 10, 20, 40mg Delayed-release OTC Tab: 20mg ADULT: 20-40mg QD PED 1-16YO: 5-20mg QD Suppresses gastric secretion by inhibiting the gastric H+, K+ ATPase at the secretory surface of parietal cells
Protonix Pantoprazole PPI (proton pump inhibitor) GERD, Gastric Hypersecretion Oral, IV; Delayed-release Tab: 20-40mg Delayed-release granules for susp: 40mg Powder for Inj: 40mg ADULT: 40-80mg QD-BID PED: 5YO+: 20-40mg QD Suppresses gastric secretion by inhibiting the gastric H+, K+ ATPase at the secretory surface of parietal cells
Crestor Rosuvastatin HMG-CoA Inhibitor Hyperlipidemia, Hypertriglyceridemia, Atherosclerosis, Hyperlipoproteinemia, Hypercholesterolemia, Prophylaxis Oral; Tablets: 5, 10, 20, 40mg ADULT: 5-40mg QD PED: 10-17YO: 5-20mg QD Inhibits the rate-limiting enzyme (HMG-CoA) in cholesterol synthesis
Lipitor Atorvastatin HMG-CoA Inhibitor Hyperlipidemia, Hypertriglyceridemia, Hypercholesterolemia, Prophylaxis Oral; Tablets: 10, 20, 40, 80mg ADULT: 10-80mg QD PED: 10-17YO: 10-20mg QD Inhibits the rate-limiting enzyme (HMG-CoA) in cholesterol synthesis
Mevacor Lovastatin HMG-CoA Inhibitor Hypercholesterolemia, Prophylaxis, Arteriosclerosis Oral; Tablets: 10, 20, 40mg ADULT: 10-80mg QD PED: 10-17YO: 10-40mg QD w/dinner Inhibits the rate-limiting enzyme (HMG-CoA) in cholesterol synthesis
Pravachol Pravastatin HMG-CoA Inhibitor Hyperlipidemia, Hypercholesterolemia, Prophylaxis Oral; Tablets: 10, 20, 40, 80mg ADULT: 40-80mg QD PED: 8-13YO: 20mg QD 13-18YO: 40mg QD Inhibits the rate-limiting enzyme (HMG-CoA) in cholesterol synthesis
Zocor Simvastatin HMG-CoA Inhibitor Hypercholesterolemia, Hypertriglyceridemia, Prophylaxis Oral; Tablets: 5, 10, 20, 40mg ADULT: 5-80mg QD PED: 10-17YO: 10-40mg QD Inhibits the rate-limiting enzyme (HMG-CoA) in cholesterol synthesis
Vytorin Ezetimibe/ Simvastatin COMBO: HMG-CoA Inhibitor & Intestinal Cholesterol Inhibitor Hyperlipidemia, Hypercholesterolemia Oral; Tablets: 10/10, 10/20, 10/40, 10/80 ADULT: Ezetimibe (1st strength): 10mg QD Simvastatin (2nd strength): 10-80mg QD PED: N/A Simvastatin: HMG-CoA Inhibitor Ezetimibe: Intestinal cholesterol inhibitor
Zetia Ezetimibe Cholesterol Absorption Inhibitor Hypercholesterolemia, Hyperlipoproteinemia Oral; Tablet: 10mg ADULT: 10mg QD PED: 10YO+: 10mg QD Inhibits absorption of cholesterol at the brush border of the small intestine via the sterol transporter NPC1L1
Lovaza Omega-3 Ethyl Esters Omega-3 Fatty Acid Hypertriglyceridemia Oral; Softgel Capsule: 1g ADULT: 4g QD (or divided) PED: N/A Not completely defined
Niaspan Niacin Nicotinic Acid Hyperlipidemia Oral; ER Tablets: 500, 750, 1000mg ADULT: 100-1000mg TID (max of 4500mg/day) PED: 100-250mg QD (divided into 3 doses) Precise MOA unknown
Pepcid Famotidine Histamine H2 Antagonist Duodenal Ulcer, Dyspepsia, Esophagitis, Gastric Ulcer, GERD, H. Pylori Eradication, Multiple Endocrine Adenoma Syndrome, Pyrosis, Systemic Mastocytosis, Zollinger-Ellison Syndrome Oral, IV; Tablets: 20 or 40mg; AC 10mg tablet or gelcap Premixed Inj. Soln.: 10mg/ml, 20mg/50ml Powder For Susp: 40mg/5ml Complete Chew Tab ADULT: 20-160mg QD or BID PED: 0-16YO: 0.5mg/kg QD or BID Inhibits the binding of histamine to H2 receptors on the gastric basolateral membrane of parietal cells, reducing basal and nocturnal gastric acid secretions
Zantac Ranitidine Histamine H2 Antagonist GERD, Duodenal Ulcer Disease, Gastric Ulcer, Indigestion Oral, IV; Syrup: 75mg/5ml or 150mg/10ml Tablets: 75, 150, 300mg Inj. Soln.: 1mg/ml or 25mg/ml Granules for Soln.: 150mg Effervescent Tab: 25 or 150mg ADULT: 150-300mg QD or BID IV: 50mg Q6-8hrs PED: 1mo-16YO: 2-4mg/kg/day Oral or IV Competitive reversible inhibitor of histamine at H2 receptors
Tricor; Trilipix; Antara Fenofibrate Fibric Acid Hypercholesterolemia, Hypertriglyceridemia Oral; Tricor: 48 or 145mg tab; 54 or 160mg micronized tab; 67, 134, 200mg micronized cap Trilipix: 45 or 135 DR cap Antara: 43, 87, or 130mg cap ADULT: 40-160mg QD PED: N/A Precise MOA unknown; lipid regulating agent
Welchol Colesevelam Bile Acid Sequestrant Hypercholesterolemia, Hyperlipoproteinemia, Type 2 Diabetes Mellitus Oral; Tablet: 625mg Powder for Susp: 3.75g 1875mg BID or 3750mg QD ADULT: 3 tabs BID or 6 tabs QD; 1.875 gram packet BID or 3.75 gram packet QD PED: 10-17YO: 3.75 gram packet QD Binds with bile acids in the intestine to form an insoluble complex that is eliminated in the feces
Zofran Ondansetron Serotonin Receptor Antagonist, 5-HT3 (Antiemetic) Chemotherapy, Radiation, Postop induced N/V Oral, IV, IM; Tablets: 4, 6, 24 mg ODT: 4 or 8mg Inj. Soln.: 2mg/ml or 32mg/50ml in dextrose 5% Oral Soln.: 4mg/5ml ADULT: 4-8mg up to TID (max 24mg/day) PED: 4-11YO: 4-8mg Q8hrs Selective 5-HT3 receptor antagonist
Created by: scottamus123