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1st set

General anesthetics are given as inhaled or intravenous agents
General anesthetics they cause Loss of Conciousness
Local Anesthetics are injected to block Nerve conduction
Local anesthetics they cause Loss of Sensation
4 stages of general anesthesia Analgesia, Excitement, Surgical Anesthesia, Medullary Paralysis
Anesthesia Induction Depends on how fast anesthesia reaches CNS
Anesthesia Recovery Depends on how slow Anesthesia is Removed from CNS
Inhaled agents are Halothane, Enflurane, Sevoflurane, Isoflurane, Nitrous Oxide. (HE SIN )
Minimum Alveolar Concentration (MAC) the higher the MAC, the higher the concentration needed for Anesthesia. High MAC, Low Potency
Halothane It has Pleasant odor, it decreases heart rate and cardiac output. its used in pediatrics. when toxic can cause halothane hepatitis and its seen with malignant hyperthermia
Malignant Hyperthermia Fatal reaction to any inhaled Anesthetics which lead to hyperthermia. Dantrolene is its Treatment
Enflurane Enflurane isn't used in patients with kidney failure, there's Seizure disorder, there's increased Inter-cranial Hypertension
Isoflurane there's Decreased Inter-cranial Pressure, it maintains CO and Coronary function
Nitrous Oxide Odorless, No muscle relaxation, Incomplete Anesthesia, Must be combined with something else.
Intravenous Agents Non opioid that controls Mild - Moderate Pain. Opioid that controls Senses to pain
Intravenous Agents Thiopentone, Ketamine, Fentanyl, Propofol, Etomidate
Thiopentone (Non opioid) Used for the brain, Decrease brain blood flow, used in short surgical procedures, causes laryngospasm
Ketamine (Non opioid) Dissociative Anesthesia, Cardiovascular stimulant, Increases Brain blood flow, Used during war for treatment, used in emergency surgeries.
Fentanyl (opioid) Used in Cardiac surgery, can causes respiratory problems. can causes muscle problems.
Propofol (Non opioid) used for short surgery, Micheal jackson used it, its immediately used by liver and excreted through Urine
Etomidate (Non opioid) causes after operation Nausea and vomiting, Lower plasma levels, Lowers cortisol Levels
Local Anesthetics they are known for their Ester Bond or Amide Bond . they also block Na+ channels.
Ester Bond Anesthetics Cocaine, Benzocaine, Procaine, Tetracaine
Amide Bond anesthetics Lidocaine, Mepivacaine, Bupivacaine, Prilocaine
Antipsychotic Drugs block Cholinergic Receptors, Adrenergic Receptors, Muscarinic Receptors, Histamine Receptors, Dopamine Receptors
Schizophrenia Brain disorder that runs in families . it shows in Late teen years and Early adult years
Schizophrenia Positive signs are Delusion, Hallucination, Loose association, Fragmented thoughts
Schizophrenia Negative signs are Introversion, low self esteem
Schizophrenia cognitive (applying knowledge) signs are Poor memory, attention deficit disorder
Schizophrenia affective (mood,feelings) signs are Depression, Elation, Suicidal thoughts
Metabolism / Administration of Antipsychotics occur by Cytochrome p450 in the Liver
Traditional Antipsychotics classes are Phenothiazines, Butyrophenones, Dibenzoxazepines, Thioxanthines, Benzisoxazoles. they work on positive symptoms of schizophrenia, their side effect are Extrapyramidal, Anticholinergic and Phenothiazines can cause Failure to Ejaculate
Phenothiazines ChlorPromazine, Fluphenazine, Thioridazine, Perphenazine
Chlorpromazine for Hiccups
Thioridazine Pigmentary Retinopathy, Cardiac Arrhythmias
Created by: slinger101



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