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Neuro& Sensory pharm
Neuro pharm
| Question | Answer |
|---|---|
| choice drug for TX status epileticus? | Ativan/dilatine |
| Barbiturates block these to help prevent seizures | nerve impulses |
| the use of valproic acid may damage this organ? | liver |
| Depakote increases levels of this neurotransmitter | GABA |
| The first line of TX for parkinson's | Levadopa |
| Increasing of this neurotransmitter is the foundation for TX of Parkinson's | Dopamine |
| Combining levadopa with this drug reduces side effects by lowering the dose needed | carbidopa |
| This drug treats Parkinson's as well as the flu? | symmetrel |
| A pt with this eye disease should not be given anticholinergics | Glaucoma |
| To much of this neurotransmitter is seen in pt with Schizophrenia | Dopamine |
| Anticholinergic may cause this bowel problem | consitpation |
| Anitcholinergics may reduce tremors in this disease | parkinson's |
| Pilocarpine causes this to contract | Iris |
| Pt's on long term steroid use are at risk for this eye disease | Cataracts |
| This fluid doesn't drain properly in glaucoma pt's | Aqueous Humor |
| Timoptic reduces this ? | Intraocular pressure (IOP) |
| First symptom of MG | Ptosis |
| This drug is used to test for MG | Tensilon |
| A Myasthenic crisis would require doing this with their medication | increase the dosage |
| Mytelase increases transmission at these receptor sites | Acetylcholinese |
| This class of drugs are the most common use in TX of MG | Anti-cholinesterase |
| This drug is used as an antidote for a Cholinergic Crisis | Atropine |
| Spasticity is commonly treated with this drug | Baclofen |
| Mannitol is used to treat this brain disorder | Cerebral edema |
| A side effect of Parkinson's that may appear odd | Dyskinesia |
| This vitamin promotes the breakdown of Levadopa | Vit-B6 |
| Timoptic is used for this condition | Glaucoma |
| Why is Levadopa given multiple times daily | bc its action has a short duration |
| Medications used to tx MS | Bacolfen(linresal)Analgesics, immunosuppressive agents,steriods GABA agonist,Benzodiazepines(valium) Symmetrel,Cylert,Prozac,inderal, Vitamin-C, ABX and Neurontin |
| Baclofen is used To TX symptoms of | Spasticity due to MS & spinal cord injuries |
| what are anticholinesterase drugs used for? | TX of Alzheimer disease & myasthenia gravis |
| drugs used to TX Alzheimers | Cognex,Aricept,Namenda, Ativan, Haldol,Razadyne Exelon |
| Medications used to TX epilepsy | Carbamazepine(tegretol) Clonazepam(Klonopin) Phenyton(Dilantin) Luminal(Phenobarbitol) esp in children Valporic Acid(Depakene) |
| How do barbiturates help TX seizures? | Depress abnormal nerve impulses discharged in the CNS |
| What blood test are monitored when adminstering Valporic Acid | liver function test/ALT |
| How does valporic Acid work | Controls certain seizures by lessening their severity & frequency by increasing GABA, and stabilizing cell membrane |
| Agents used to TX Parkinson's | (BALSA)Bromocriptine, Amantadine, Levadopa/Carbidopa, Selegiline & Antimuscarinics |
| Tx Parkinsonism; to relieve tremors & rigidity.NOT used to TX drug related parkinson's | Carbidopa/Levodopa (Sinemet) |
| Decreases symptoms of Parkinsonism & increases mobility | Levodopa/Carbidopa (Sinemet) |
| S/E of Carbidopa/Levodopa | anorexia,n/v,dysphagia,fatigue, dizziness,headache,dry mouth, bitter taste,twitching, blurred vision,insomnia & dark urine |
| Benefits of combining Levodopa/carbidopa | 1. more Dopamine reaches the basal ganglia 2.Smaller doses of Levodopa are required to achieve the desired effect |
| Intended effects of Levodopa | when introduced ,L-dopa is effective in diminishing symptoms of Parkinson's disease & increasing mobility |
| Progressive deterioration of dopaminergic neurons in the brain/side effects of drugs that mask parkinsons | Parkinsonism |
| Levodopa is contraindicated in Parkinson pt with | narrow angle glaucoma |
| Valium,Dantrium,Baclofen are what type of drugs | muscle relaxants |
| S/E of Baclofen | Hypotension,Hyperglycemia |
| How do TX for Parkinson work | By increasing the level of dopamine |
| how often are meds for Parkinson given | Around the clock |
| What vitamin causes destruction of common drugs for Parkinson's | Vit-B6 |
| medication used for advanced stages of parkinson's | Levodopa/Carbidopa/ Entacapone (stalevo) |
| medication to be given if pt couldn't tolerate first line drug | Beneztropine & Procyclidine |
| what pt experience decreased levels of Acetylcholine | MG |
| S/E of cholinergic drugs | Respiratory depression, clenched jaw excessive salvation |
| S/S ofcholinergic toxicity | cholinergic crisis |
| condition that is contraindicated when prescribing Anticholinergic drugs | Glaucoma |
| what symptom is Baclofen used to TX | Spacitity |
| long term use of this type of drug can lead to cataracts | steroids |
| drugs that TX nerve disorders | Tegretol,Carbatrol,Epitol, Equetro (Carbamazepine) |
| drug used to decrease ICP | Manitol |
| Antidote for overmedication | Atropine |
| What does GABA do | blocks nerve impulses |
| Sinemet, a drug used to TX parkinsons is a combo of what two drugs | Levodopa/carbidopa |
| O/D of Haldol leads to | may cause the same symptoms of Parkinsons |
| Decreased ACH stimulants leads to | use of Anticholinergic & Benezotropine |
| Anticholinergics are the same as | Atropine & Atrovent |
| pathophysiology Of AD | Atrophy of the cerebrum hippocampus > memory loss & decrease cognitive function |
| Anticholinergics to know | Benzotropin(Cogentin) Biperiden HCI (Akineton)Procyclidine HCI Benadryl |
| What medications is not used for correction of parkinsons | Dopamine |
| Dopamine is not used as a med for parkinson B/C | it does not cross the blood brain barrier |
| If a pt with parkinsons is recieving cognetin therapy it means that most likely | pt symptoms are not that severe |
| this medication for AD may cause a pt to develop a fever,sore throat & runny nose may be S/E of | Tacrine(Cognex) |
| Aricept should not be combined with this medication as they antagonize each other | Urecholine |
| S/E Gabapentine(neurontin) | depression, malaise,vertigo,weakness & ataxia |
| Used as adjunctive therapy for partial seizures enhances action of GABA | Neurontin |
| TX for acute status epilepticus & must be given IV to achieve desired response > short term effect | Phentoin(dilatin) |
| _____is allowed to cross the blood brain barrier but not__________? | Levodopa is but not Dopamine |