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Clase antiaritmice Clasa I - blocante ale Na Clasa II - blocante B adrenergice Clasa III - cresc potential de act Clasa IV - blocante ale Ca
Clasa I Ia - scad moderat depol sistolica si cresc PA Ib - scad slab depol sistolica si scad PA
Clasa Ia (medicamente-efecte) Chinidina(oral) - parasimpatolitic (doze mici) , cronotrop- , scade conductibilitatea AV, VD (blocare alfa adrenergice) Procainamida(i.v) - idem Chinidina, mai putin parasimpatolitic -> urgente aritmice
Indicatii Clasa Ia Aritmii atriale si ventriculare: flutter, fibrilatie atriala, TPSV, WPW, extrasistole
Reactii adverse Clasa Ia Hipotensiune, bradicardie, agravare BAV , ochi, tinnitus, cefalee, greata, varsaturi.
Clasa Ib (medicamente) Lidocaina (i.v) , fenitoina (oral) - se poate folosi cu digitalice, deoarece nu scade viteza de conducere AV , mexiletina
Clasa Ic (medicamente) encainida, flecainida
Clasa III (medicamente) amiodarona, sotalolul, bretiliul
Reactii adverse amiodarona Acumulare in tesuturi: miocard (proaritmogen), pulmonar ( fibroza) , tegument (fotodermita), microdepozite corneene, hipotiroidism
Clasa IV (medicamente) verapamil, diltiazem
Clasa IV (efecte) cronotrop, batmotrop, dromotrop, inotrop -, VD
Indicatii clasa IV Aritmii SV
Created by: rapul