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Module 3

Generic NameTrade NameClassTherapeutic UsesSide EffectsNursing Implications
Rivastigmine Exelon Cholinesterase Inhibitor- irreversible Mild to Severe Alzheimer's Cholinergic Side effects: Nausea, Vomiting NONE
MEMANtine NAMENda NMDA receptor antagonist -mimics glutamate=excitatory Mod. to Severe Alzheimer's NONE 7%-Dizziness Watch pts with renal problems.
aRICEpt (RICE DONE) DONEpezil Cholinesterase Inhibitor- reversible Mild to Moderate Alzheimer's Nausea NONE
Phenytoin Dilantin AED- Na+ Inhibition to active state Epilepsy, heart dysrhythmias GINGIVAL HYPERLASIA! Nystagmus-cyclical eye mvmnt. Tell pts: Take w/ food, take as Rxed, Sedation can occur, teach dental health.
Carbamazepine Tegretol AED- Na+ inhibition to active state Epilepsy, Bipolar Disorder, Trigeminal and glossopharyngeal neuralgias Leukopenia, thrombocytopenia, Birth defects, headache, visual problems. Tell pts: NO GRAPEFRUIT JUICE!!! Take w/ food, discuss symptoms of hematological abnormalities.
Valproic Acid Depakote, Depakene, Depacon AED Seizure Disorders, Bipolar, Migraines GI upset, Hepatotoxicity, Pancreatitis, Teratogenesis Tell pts: Take with food, educate on symptoms of liver injury, Folic acid for pregnant women
Phenobarbital NONE AED - Barbituate Epilepsy-Partial & Tonic-Clonic seizures, Sedation Drowsiness, Physical Dependence Warn pts of sedative effects and poss. birth defects.
Diazepam Valium Benzodiazapine-Skeletal Muscle Relaxant (Acts by enhancing GABA), Antianxiety Spasticity, STATUS ELIPTICUS!!!! Sedation
Baclofen Lioresal Mimics GABA on spinal neurons Spasticity due to MS or spinal cord lesions No Serious ones. Obtain LFTs. Warn pts about depressant/sedative effects.
DANTrolene DANTrium Skeletal Muscle Relaxant (Acts directly on smooth muscle) SPASTICITY assoc. w/ MS, Cerebral Palsy, Spinal Cord Injury. MALIGNANT HYPERTHERMIA Hepatic Toxicity Obtain LFTs. Warn pts about depressant/sedative effects
Levetiracetam Keppra AED Epilepsy
Benztropine (think aTROPINE,which is a???) Cogentin (Cog-Cognition-declines w/ disease this txs) Anticholinergic agent- blocks mus. receptors in striatum Parkinson's
Anti-Eplieptic Drugs AED AED Minimize seizures CNS Depression, Withdrawal seizures from abrupt Rx Stop, Suicidal Thoughts Teach pt to maintain seizure info chart, carry form of ID, Avoid driving, NEVER stop meds, take folic acid (if pregnant), avoid alcohol.
Lorazepam Ativan
Pregabalin Lyrica Fibromyalgia, Post-herpatic neuralgia
Gabapentin (GABA=inhibitory=used for?!) Neurontin Seisures, post-herpatic neuralgia, peripheral neuropathy pain
TOPiramate TOPamax
Alzheimer's Drugs Exelon Namenda Donepezil
Epilepsy Drugs Dilantin Tegretol Depakote Phenobarbital Keppra Gabapentin Status Elipticus Drug Valium (Diazepam)
Spaticity Drugs Valium Lioresal Dantrium
Parkinson Drugs Cogentin Dopar Sinemet/Paracopa MiraPEX
Levodopa Dopar Promotes dopamine syn. Parkinson's Nausea, vomiting, Dyskinesias, dysrhythmias,Orthostatic hypotension, Psychosis. Drug Holidays Recommended. Take w/ food to decrease nausea and vomiting. High-protein meals should be avoided!!
Carbidopa (Combo w/ Levodopa) Sinemet Paracopa Inhibits breakdown of Levadopa in the periphery= higher [] to the brain. Parkinson's NONE Same as Levadopa.
PramiPEXole MiraPEX Dopamine Agonist Parkinson's, RLS-Restless Leg syndrome Nausea, vomiting, Orthostatic Hypotension, Dyskinesias, Hallucinations, Compulsive behaviors. Inform pts about: taking Rx w/ food, Symptoms of orthostatic hypotension, Possibily of a sleep attack, and hallucinations.
Created by: ederight



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