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Pharm 2 final
Final
Question | Answer |
---|---|
Androgen drug | Striant (testosterone) |
Androgen drug action, use (2), s/e (8) | action - use - hypogonadism & delayed puberty, s/e - n/v/acne, hair thinning, anxiety, mood changes, electrolyte & fluid imbalance, hepatotoxicity |
Oxytocic agent drug | Pitocin (oxytocin) |
Oxytocic agent action | enhance uterine motility by stimulating uterine smooth muscle to contract |
Cardiotonics Drug | Digoxin |
Cardiotonic Action & Use (3), S/E (10) | Action - Drug stimulates heart muscle to beat more forcefully & slowly; Use - CHF, treat tachycardia fib and flutter, stimulate - makes heart beat slower; N/V/anorexia, weakness, fatigue, fainting, hypotension, bradycardia, visual disturbances, arrthymias |
Cardiotonic NI (9) | Digitalization, given loading dose then q2hrs after, dose is 0.125-0.25mg qd, watch K levels b/c hypokalemia - digoxin toxicity, k supplement, monitor HR, rhythm, daily wt & I&O, therapeutic blood levels for weeks after start of therapy, levels 0.8-2 |
Nitrate Family Drug | Isordil |
Nitrate Family Action | Dilate arteries & arteriloes in periphery thereby decreasing BP, the reduce BP greatly reduces work load of heart, lowering O2 demand |
Coagulant Drug | Amicar |
Coagulant Action | Helps formation of blood clots |
Anticoagulant Oral Prep Drug | Coumadin |
Anticoagulant Oral Prep NI | many drug interaction - check when starting Coumadin |
Drugs used to lower cholestrol & triglycerides Drug (4) (statin) | Questran, Lipitor, Pravachol, Niacin |
Questran Action | Sand like texture that stays in the intestine & binds biles acids. Bile acids are the degeneration products of cholestrol. The binding of bile acid by Questran mix w/fluid (4-6oz) may need vitamin supplement |
Lipitor & Pravachol Use (2), NI (2) | in conjunction w/diet therapy, they are used to decrease elevated blood concentrations & reduce risk of atheroscelerosis leading to CAD; NI - do liver fx test b4 starting therapy, then q 3-6montha, no grapefruit juice |
Parenteral Anicoagulant Drug | Heparin sodium |
Parenteral Anticoagulant Uses (4) NI (2) | Prevents post-op DVT & pulmonary embolus in pt undergoing some surgical proc, prevent cerebral thromboses in pt who had stroke, trmt of coronary occulsion or acute MI, maintain patency of IV caths; NI - antedote is protemine sulfate; test is PTT or APTT |
ACE inhibitor drug | Capoten |
ACE inhibitor use (2)/NI (2) | use - hypertension; heart failure after MI; NI - no K rich foods, no salt substitutes |
Calcium Channel Blocking Agents Drugs | Procardia & Cardizem |
Calcium Channel Blocking Agents Action | Block calcium ion flow across smooth & cardiac muscle, decrease O2 demand, cardiac output, dilating coronary arteries & arteroles |
Calcium Channel Blocking Agents Use | hypertension, angina, arrthymias |
Oral contraceptive drugs | estrogen/progestin drug & progestin only |
Oral contraceptive action (2) | stop ovulation; prevent ovaries from developing folical, alter cervical muscus, thus inhibiting sperm migration & impair implantation, of fertilized ovum. |
Antiadrenergic Drug | Aldomet |
Antiadrenergic Drug Action & NI | Action - decrease activity of SNS; NI-BOSE |
Antiarrythmic Agents Drugs (3) | Dilantin, Cardizem, Pronestyl |
Dilantin use, SE, NI | anticonvulsant - only used to treat digoxin induced arrthymias, s/e - CNS depressant drug, NI - monitor VS |
Pronestyl Use | wide variety of atrial fib & flutter |
Antidotes (3) | warfin - vitamin K; sulfate - herparin; beta blocker - atropine & isuprel |
ferrous sulfate s/e (3) | lowered vitality; pallor; breathlessness |
calcium channel blocker NI (2) | hypotension & edema |
pronestyl action (3) | cardiac depressant & antiarrthymic - quite heart muscle |
MAO inhibitors NI (6) | BP & pulse before and during trmt; contrindictated in liver, renal, CVD, & elderly pts |
Antianxiety drug | valium |
Valium s/e (4) | drowsiness, dizziness, ataxia, palpatations |
Potassium removing drug | Kayexalate |
Kayexalate use | hyperkalemia |
Antidysrhythmic drug | Xyelocaine |
Xyelocaine use, NI | use - drugs of choice to treat ventricular tachycardia & ventricular fib; NI - BOSE - BP |