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Farmaco

Antiasmatice

QuestionAnswer
Mecanisme de actiune bronhodilatatie simpatomimetica, bronhodilatatie parasimpatolitica, musculotropa, glucocorticoizi (AIS) , antagonistii recep leucotrienelor si inhib ai lipooxigenazei
Durata de actiune a simpatomimeticelor: adrenalina, izoprenalina, salbutamol, terbutalina, fenoterol, salmeterol adrenalina( a si b recep) + izoprenalina (b) -> durata scurta (tratamentul crizelor de astm) salbutamol + fenoterol + terbutalina (b2 selec) -> durata medie salmeterol -> durata lunga (profilaxie)
Bronhodilatatoare simpatomimetice Adrenalina, izoprenalina, salbutamol, orciprenalina,terbutalina, fenoterol, salmeterol
Bronhodilatatoare parasimpatolitice Atropina, Ipatropiul, Oxitropiu
Bronhodilatatoare musculotrope teofilina, aminofilina (teofilina + etilendiamina) , diprofilina
Reactii adverse teofilina Greata (creste secretia gastrica) , cefalee, palpitaii + tahicardie + aritmii (stim. miocardul) , anorexie, insomnie, nervozitate
Inhibitoare ale degranularii mastocitare Acidul cromoglicic (cromoglicat de sodiu), nedocromilul, ketotifen
Glucocorticoizi in astm Inhalator - beclametazona dipropionat Oral - prednisol IV - hemisuccinat de hidrocortizon IM - triamcinolona acetonid, metilprednisol acetat
Antagonisti leucotrienelor Montelukastul, zafirlukastul, zileutonul
Created by: rapul
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