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Cardio
Pharm
| Question | Answer |
|---|---|
| Cardiotonic drugs (2) | Digoxin & digitoxin |
| Cardiotonics Action | Drug stimulates heart muscle to beat more forcefully & slowly |
| Cardiotonics use | CHF, treat tachycardia fib and flutter, stimulate - makes heart beat slower |
| Cardiotonics S/E (10) | N/V/anorexia, weakness, fatigue, fainting, hypotension, bradycardia, visual disturbances, arrthymias |
| Cardiotonics NI (9) | Digitalization, given loading dose then q2hrs after, dose is 0.125-0.25mg qd, watch K levels b/c hypokalemia - digoxin toxicity, k supplement, monitor HR, rhythm, daily wt & I&O, therapeutic blood levels for weeks after start of therapy, levels 0.8-2 |
| Antiarrythmic Agents Drugs (4) | Dilantin, Inderal, Quinaglute, Cardizem |
| Dilantin Action | decrease excitability of myocardial tissue |
| Inderal uses (7) | angina, cardiac arrthymias, hypertension, after MI to prevent recurrence, migraine, headaches, stage fright |
| Quinaglute Action & Uses (2) | action - Works on heart muscle stabilizing the rate of conduction of impulses; use - arrthymias, atrial fib & flutter |
| Cardizem Action | Block calcium ion flow across smooth and cardiac muscle, decrease cardiac output, O2 demand, dilate arteries and arterioles |
| Nitrate Family Drugs (4) | Isordil, Nitro-Dur, Nitro-Bid, Nitrostat |
| Nitrate Family Action | Dilate arteries & arteriloes in periphery thereby decreasing BP, the reduce BP greatly reduces work load of heart, lowering O2 demand |
| Nitrate Use | treat/prevent angina - read notes |
| Nitrate S/E (5) | flushing, hypotension, headache, dizziness, tolerence |
| Nitrate NI (2) | BP & Apical for 1 min; <60 hold and call Dr |
| Beta-Blockers Family Drugs (3) | Inderal, Lopressor, Tenormin |
| Beta-Blocker Action | Block Beta 1 receptors, decrease cardiac output, O2 consumption, peripheral resistence & depress renin secretions |
| Calcium Channel Blocking Agents Drugs (2) | Cardizem & Procardia |
| Calcium Channel Blocking Agents Action | Block calcium ion flow across smooth & cardiac muscle, decrease O2 demand, cardiac output, dilating coronary arteries & arteroles |
| Peripheal Vasodilating Agents Drug | Pavabid |
| Pavabid Action | peripheal dilator |
| Antiadrenergic Drugs (2) | Aldomet & Catapres |
| Aldomet Action | decrease activity of SNS |
| Catapres Action | Inhibit activity of SNS, HR & decrease cardiac output |
| Vasodilating Drug | Aprseoline |
| Vasodilating S/E (4) | edema, orthostatic hypotension, loss of appetite, lupus like syndrome - sx include fever,joint pain, chest pain, edema |
| Beta 1 & Beta 2 Blocking Agents (4) | Inderal, Lopressor, Tenormin, Visken |
| Beta 1 & Beta 2 Blocking Agents Action | Block stimulation of both Alpha & Beta receptors resulting in peripheal - vasodilation |
| Hypertensive Emergency Drug | Nipride |
| Hypertensive Emergency Use | Treat emergency hypertension w/impending organ damange, usually of brain, heart & eyes |
| Coagulant Drug | Amicar |
| Coagulant Action | Helps formation of blood clots |
| Parenteral Anicoagulant Drug | Heparin sodium |
| Parenteral Anticoagulant Uses (4) | Prevents post-op DVT & pulmonary embolus in pt undergoing some surgical procedures, prevent cerebral thromboses in pt who had stroke, treatment of coronary occulsion or acute MI, maintain patency of IV caths |
| Anticoagulant Oral Prep Drug | Coumadin |
| Anticoagulant Oral Prep Action | Inhibits action of vitamin K which is required for activation of clotting factors |
| Anticoagulant Oral Prep NI | many drug interaction - check when starting Coumadin |
| Thrombolytic Agent Drug | Streptase |
| Thrombolytic Agent Action | Promote the disolution of insoluable fibrin, trapped in intravascular emboli & thrombi |
| Drugs used to lower cholestrol & triglycerides Drugs (2) | Mevacor & Questran |
| Mevacor Action | Inhibit & manufacture of cholestrol or promote breakdown of cholestrol |
| Mevacor S/E (4) | Headache, abdominal blotting, increase liver fx test, myopathy includes muscle aches, soreness & weakness |
| Questran Action | Sand like texture that stays in the intestine & binds biles acids. Bile acids are the degeneration products of cholestrol. The binding of bile acid by Questran mix w/fluid (4-6oz) may need vitamin supplement |
| cardizem categories (3) | antiarrthymic, calcium channel blocking, anti-hypertensive |
| inderal categories (3) | antiarrthymic, beta-blocker (anti-anginal and anti-hypertensive) |
| lopressor and tenormin categories (2) | anti-anginal and anti-hypertensive |