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CH 25, 26, 27
Antihypertensives, Antidysrhythmics, Cardiac Glycosides
| Generic Name | Trade Name | Uses | Side Effects |
|---|---|---|---|
| digitoxin, digoxin | Lanoxin | Increased myocardial contractility. Helps with CHF. Helps reduce heart size and decreases venous pressure to relieve edema. Positive inotropic, negative chronotropic, negative dromotropic actions. | anorexia, nausea, bradycardia, stomach pain, dysrhythmias. |
| digoxin immune Fab (Ovine) | Digibind | Antidote for severe digitalis toxicity. | (blank) |
| inamrinone | Inocor | Increases force and velocity of myocardial tissues. Positive inotropic effect | n/v, abdominal pain, fever, taste alterations, chest pain. |
| quinidine (Group I-A) | Quinora | Antidysrhythmic. Decrease conduction velocity | anorexia, bitter taste, n/v, abdominal distress, flushing, rash, tinnitus, confusion |
| lidocaine (Group I-B) | Xylocaine | local and topical anesthetic and antidysrhythmic, especially for ventricular dysrhythmias after cardiac surgery or MI. | dizziness, anorexia, n/v, chest pain, and breathing difficulties. |
| propranolol (Group II) | Inderal | Control cardiac dysrhythmias caused by excessive sympathetic nerve activity. | (blank) |
| amiodarone | Cordarone | Increases refractory period in all cardiac tissues. Decreases automaticity, prolongs AV conduction, and decreases the automaticity of Purkinje fibers. | dizziness, bitter taste, headache, flushing, n/v, constipation, weight loss, numbness and tingling in fingers, fever, dyspnea. |
| adenosine | Adenocard | Slow AV node conduction. Converts paroxysmal supraventricular tachycardia to normal sinus rhythm. | dyspnea, flushing, nausea, headache, dizziness, tingling in arms, sinus tachycardia, sinus bradycardia, skipped beats. |
| clonidine | Catapres | Decreased CO, heart rate, and peripheral vascular resistance. Prophylaxis of migraine or vascular headaches. Treats Tourette's syndrome. Nicotine/opioid withdrawal. | dry mouth, headaches, constipation, weakness, postural hypotension, impotency, insomnia, anxiety, anorexia, nausea, vomiting, pruritis. |
| methyldopa | Aldomet | Safe for pregnancy. Decreased CO, heart rate, peripheral vascular resistance. | drowsiness, dry mouth, headaches, edema of feet and legs, postural hypotension, impotency, insomnia, depression, anxiety. |
| prazosin | Minipress | Decreased Peripheral vascular resistance. Adjunct therapy to digoxin and diuretics in treatment of CHF. | weakness, n/v, stuffy nose, orthostatic hypotension, angina, edema,, headaches, syncope, SOB |